Recombinant Anti-Human FOLR1 Antibody (Fc glycosylation/Non fucosylated)

Name: Recombinant Anti-Human FOLR1 Antibody (Fc glycosylation/Non fucosylated)
SKU: Gly-029LC
Rating: 5 (1 reviews)

CAT#: Gly-029LC

This product is a human monoclonal antibody with N-glycosylation site Asn299 in the heavy chain. Antibody MORAb-003 has increased ADCC, it specifically binds human FRA and can be potentially used in the treatment of FRA-mediated disease such as cancer.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line HeLa

Immunofluorescent staining of human cell line HeLa shows localization to nuclear membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/77030/1659_B3_2_selected.jpg

RNA Expression Figure 2 RNA cell line category: Group enriched (HeLa, RPTEC TERT1)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000110195-FOLR1

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Glyco-engineering

Glycosylation site
Asn299 of heavy chain

Glycoform (ratio)
NGA2

Glycosylation Type
N-glycosylation

Activity
Increased ADCC

Specifications

Target
FOLR1 (Folate receptor alpha)

Host Species
Human

Type
Human antibody

Specificity
Human

Clone
MORAb-003

Expression Host
CHO-K1

Applications
ELISA

Target

Alternative Names
FOLR1; folate receptor 1 (adult); FBP; FOLR; folate receptor alpha; FR-alpha; KB cells FBP; folate binding protein; folate receptor, adult; adult folate-binding protein; ovarian tumor-associated antigen MOv18;

Related Disease
FRA-mediated disease

Gene ID
2348

UniProt ID
A0A024R5H1

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Downloadable Resources

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Datasheet

Datasheet - Gly-029LC.pdf

MSDS

MSDS - Gly-029LC.pdf

COA

Certificate of Analysis Lookup

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