AbPlus™ Anti-AXL Magnetic Beads (VS-0424-XY26)
CAT#: VS-0424-XY26
The AbPlus Anti-AXL Magnetic Beads (VS-0424-XY26) is an innovative affinity resin which is bound with anti-AXL specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of AXL protein under native and denaturing conditions.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, actin filaments & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/75217/1899_C1_1_selected.jpg
Normal Tissue
Figure 2 IHC staining of human thyroid gland
Immunohistochemical staining of human thyroid gland shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32501/ihc_selected.jpg
Normal Tissue
Figure 3 Skeletal muscle
Myocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_B_1_6.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_8_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_9_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_4_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (fHDF/TERT166, U-251 MG)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167601-AXL
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Specifications
- Applications
- Immunoprecipitation, Protein Purification
- Matrix
- Magrose bead (> 50 μmol/mL gel)
- Bead Ligand
- Anti-AXL specific antibody
- Target
- AXL
- Target Species
- Human
- Bead Capacity
- 20-30 mg/mL binding antibody
- Bead size
- 10-37 μm
- Stability
- pH 2-14
- Format
- 20% Suspension
- Buffer
- PBS, pH 7.4, with 1% BSA
- Preservative
- 0.03% Proclin 300
- Storage
- Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.
Applications
- Application Notes
- The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.
Target
- Introduction
- The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.
- Alternative Names
- AXL Receptor Tyrosine Kinase; AXL Oncogene; EC 2.7.10.1; UFO; Tyrosine-Protein Kinase Receptor UFO; AXL Transforming Sequence/Gene
- Gene ID
- 558
- UniProt ID
- P30530
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Related Diseases
EGFR Tyrosine Kinase Inhibitor Resistance
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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See other products for "AXL"
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0138CL | Mouse Anti-AXL Recombinant Antibody (TAB-0138CL) | ELISA, IF, FC, Inhib, ICFC | |
| TAB-0335CL-S(P) | Anti-Human AXL Recombinant Antibody scFv Fragment (Ax225 (was demonstrated to recognize FND1 of AXL)) | WB, FuncS, ELISA | |
| TAB-0336CL-S(P) | Anti-Human AXL Recombinant Antibody scFv Fragment | WB, FuncS, ELISA | |
| TAB-1087CL-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (TAB-1087CL-S(P)) | ELISA, FuncS | Mouse scFv |
| TAB-1088CL-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (TAB-1088CL-S(P)) | ELISA, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0139CL | Anti-Human AXL Recombinant Antibody (hzl613F12-24 DAR2) | ELISA, IF, FC, Inhib, ICFC | Humanized Antibody |
| TAB-0140CL | Anti-Human AXL Recombinant Antibody (hzl613F12-33 DAR4) | ELISA, IF, FC, Inhib, ICFC | Humanized Antibody |
| TAB-1094CL | Anti-Human AXL Recombinant Antibody (Hz1613F12) | ELISA, FC, Cyt | Humanized antibody |
| TAB-0139CL-S(P) | Anti-Human AXL Recombinant Antibody scFv Fragment (hzl613F12-24 DAR2) | ELISA, IF, FC, Inhib, ICFC | Humanized Antibody |
| TAB-0140CL-S(P) | Anti-Human AXL Recombinant Antibody scFv Fragment (hzl613F12-33 DAR4) | ELISA, IF, FC, Inhib, ICFC | Humanized Antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1090CL | Human Anti-AXL Recombinant Antibody (TAB-1090CL) | ELISA, FuncS | Chimeric (mouse/human) IgG1, κ |
| TAB-1091CL | Human Anti-AXL Recombinant Antibody (TAB-1091CL) | ADCC | Chimeric (mouse/human) IgG1, κ |
| TAB-1092CL | Human Anti-AXL Recombinant Antibody (TAB-1092CL) | ADCC | Chimeric (mouse/human) IgG1, κ |
| TAB-0189CL-S(P) | Human Anti-AXL Recombinant Antibody; scFv Fragment (TAB-0189CL-S(P)) | WB, FuncS, ELISA, FC | Human scFv |
| TAB-0189CL-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (TAB-0189CL-F(E)) | WB, FuncS, ELISA, FC | Chimeric (Mouse/Human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3970 | Hi-Affi™ Rabbit Anti-AXL Recombinant Antibody (clone SI30DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0600-CN | Human Anti-AXL Recombinant Antibody (HPAB-0600-CN) | SPR, ELISA, FC, WB, Inhib, FuncS, IHC, Block | Human IgG |
| HPAB-0601-CN | Human Anti-AXL Recombinant Antibody (HPAB-0601-CN) | ELISA, FC, IHC, Block | Human IgG |
| HPAB-0603-CN | Human Anti-AXL Recombinant Antibody (HPAB-0603-CN) | WB, ELISA, FC, IHC | Chimeric (Mouse/Human) IgG1, κ |
| HPAB-0604-CN | Mouse Anti-AXL Recombinant Antibody (HPAB-0604-CN) | ELISA, IHC | Mouse IgG1, κ |
| HPAB-0108-LS | Mouse Anti-AXL Recombinant Antibody (HPAB-0108-LS) | ELISA, FC, SPR, FuncS | Mouse IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1616LY-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-1616LY-F(E)) | ELISA | Humanized Fab |
| HPAB-1617LY-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-1617LY-F(E)) | ELISA | Humanized Fab |
| HPAB-1618LY-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-1618LY-F(E)) | ELISA | Humanized Fab |
| HPAB-1619LY-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-1619LY-F(E)) | ELISA | Humanized Fab |
| HPAB-M0416-YC-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-M0416-YC-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-625-FY-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-625-FY-S(P)) | WB, Inhib | Mouse scFv |
| HPAB-626-FY-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-626-FY-S(P)) | Inhib | Mouse scFv |
| HPAB-M0416-YC-S(P) | Human Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-M0416-YC-S(P)) | ELISA | Human scFv |
| HPAB-1850LY-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1850LY-S(P)) | ELISA, IA, FC, IHC, WB, IP | Mouse scfv |
| HPAB-1851LY-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1851LY-S(P)) | ELISA, IA, FC, IHC, WB, IP | Mouse scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY44 | Rabbit Anti-NHP AXL Recombinant Antibody (VS-1024-XY44) | WB, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY2 | CytoStream™ Rat Anti-AXL Recombinant Antibody (clone 175128) | FC | Rat IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY66 | Human Anti-AXL (clone Enapotamab) scFv-Fc Chimera | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC363 | Recombinant Anti-AXL Vesicular Antibody, EV Displayed (VS-0425-YC363) | ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC20 | Recombinant Anti-AXL (AA 1-134 x AA 222-234) Biparatopic Antibody, Tandem scFv | Block, ELISA, FC, IHC, SPR, WB | Tandem scFv |
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