Anti-Human AXL Recombinant Antibody (Humanized 11D5)
CAT#: TAB-1099CL
The anti-AXL antibody Humanized 11D5 targets AXL. The antibody can be used in the treatment of cancers, such as prostate cancer and breast cancer.
Published Data
Gene Expression
ELISA
Figure 1 This figure describes binding activity of the rat anti-human AXL humanized antibodies h#11 D5-T1 to h#11 D5-T6 determined by ELISA using human AXL-Fc coated plate.
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Subcellular Location
Figure 1 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, actin filaments & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/75217/1899_C1_1_selected.jpg
Normal Tissue
Figure 2 IHC staining of human thyroid gland
Immunohistochemical staining of human thyroid gland shows strong cytoplasmic positivity in glandular cells.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32501/ihc_selected.jpg
Normal Tissue
Figure 3 Skeletal muscle
Myocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_B_1_6.jpg
Normal Tissue
Figure 4 Colon
Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_8_3.jpg
Normal Tissue
Figure 5 Kidney
Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_9_5.jpg
Normal Tissue
Figure 6 Testis
Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_4_6.jpg
RNA Expression
Figure 7 RNA cell line category: Cell line enhanced (fHDF/TERT166, U-251 MG)
Cell lines ordered by descending RNA expression order
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167601-AXL
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Specifications
- Host Species
- Human
- Type
- Humanized antibody
- Specificity
- Human
- Clone
- Humanized 11D5
- Applications
- ELISA
- Related Disease
- Breast cancer, Prostate cancer
Applications
- Application Notes
- This antibody has been tested for use in Enzyme-linked Immunosorbent Assay.
Target
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Related Diseases
EGFR Tyrosine Kinase Inhibitor Resistance
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0335CL | Anti-Human AXL Recombinant Antibody (Ax225 (was demonstrated to recognize FND1 of AXL)) | WB, FuncS, ELISA | |
| TAB-0188CL-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (TAB-0188CL-S(P)) | WB, FuncS, ELISA, FC | Mouse scFv |
| TAB-1087CL-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (TAB-1087CL-S(P)) | ELISA, FuncS | Mouse scFv |
| TAB-1088CL-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (TAB-1088CL-S(P)) | ELISA, FuncS | Mouse scFv |
| TAB-1089CL-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (TAB-1089CL-S(P)) | ELISA, FuncS | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1071CLV | Human Anti-AXL Recombinant Antibody (TAB-1071CLV) | ADCC, FuncS | Chimeric (mouse/human) IgG1, κ |
| TAB-1072CLV | Human Anti-AXL Recombinant Antibody (TAB-1072CLV) | ELISA | Chimeric (mouse/human) IgG1, κ |
| TAB-1073CLV | Human Anti-AXL Recombinant Antibody (TAB-1073CLV) | ELISA | Chimeric (mouse/human) IgG1, κ |
| TAB-1074CLV | Human Anti-AXL Recombinant Antibody (TAB-1074CLV) | ELISA | Chimeric (mouse/human) IgG1, κ |
| TAB-1075CLV | Human Anti-AXL Recombinant Antibody (TAB-1075CLV) | ELISA | Chimeric (mouse/human) IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3970 | Hi-Affi™ Rabbit Anti-AXL Recombinant Antibody (clone SI30DS) | ELISA | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1783LY | Mouse Anti-AXL Recombinant Antibody (HPAB-1783LY) | ELISA, IHC | Mouse IgG2b |
| MRO-1674-CN | Rabbit Anti-AXL Polyclonal Antibody (MRO-1674-CN) | WB, IF | Rabbit IgG |
| HPAB-0936WJ | Human Anti-AXL Recombinant Antibody (clone 11B7) | ELISA, IHC | Chimeric (rat/human) IgG |
| HPAB-0937WJ | Human Anti-AXL Recombinant Antibody (clone 11D5) | ELISA, IHC | Chimeric (rat/human) IgG |
| HPAB-0445YY | Human Anti-AXL Recombinant Antibody (HPAB-0445YY) | FuncS | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1616LY-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-1616LY-F(E)) | ELISA | Humanized Fab |
| HPAB-1617LY-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-1617LY-F(E)) | ELISA | Humanized Fab |
| HPAB-1618LY-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-1618LY-F(E)) | ELISA | Humanized Fab |
| HPAB-1619LY-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-1619LY-F(E)) | ELISA | Humanized Fab |
| HPAB-625-FY-F(E) | Mouse Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-625-FY-F(E)) | WB, Inhib | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-1850LY-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1850LY-S(P)) | ELISA, IA, FC, IHC, WB, IP | Mouse scfv |
| HPAB-1851LY-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1851LY-S(P)) | ELISA, IA, FC, IHC, WB, IP | Mouse scfv |
| HPAB-1852LY-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1852LY-S(P)) | ELISA, IA, FC, IHC, WB, IP | Mouse scfv |
| HPAB-1853LY-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1853LY-S(P)) | ELISA, IA, FC, IHC, WB, IP | Mouse scfv |
| HPAB-1854LY-S(P) | Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1854LY-S(P)) | ELISA, IA, FC, IHC, WB, IP | Mouse scfv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY26 | AbPlus™ Anti-AXL Magnetic Beads (VS-0424-XY26) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY44 | Rabbit Anti-NHP AXL Recombinant Antibody (VS-1024-XY44) | WB, IF, IP | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0225-XY2 | CytoStream™ Rat Anti-AXL Recombinant Antibody (clone 175128) | FC | Rat IgG2a, kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY66 | Human Anti-AXL (clone Enapotamab) scFv-Fc Chimera | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC363 | Recombinant Anti-AXL Vesicular Antibody, EV Displayed (VS-0425-YC363) | ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC20 | Recombinant Anti-AXL (AA 1-134 x AA 222-234) Biparatopic Antibody, Tandem scFv | Block, ELISA, FC, IHC, SPR, WB | Tandem scFv |
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