Anti-Human AXL Recombinant Antibody (Hz1613F12) (CAT#: TAB-1094CL)

The anti-AXL antibody Hz1613F12 targets AXL. The antibody can be used in the treatment of cancers, such as breast cancer, NSCLC, pancreas cancer, lung cancer and renal cancer

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ELISA

Figure 1 ELISA experiments studying binding on rhAxl-Fc protein of both m1613F12 and hz1613F12.

Figure 1 ELISA experiments studying binding on rhAxl-Fc protein of both m1613F12 and hz1613F12.

FC

Figure 2 Binding of hz1613F12 and hz1613F12-24 DAR4 and DAR2 to SN12C human renal tumor cells as determined by FACS analysis. Data represent the mean intensity of fluorescence obtained over a range dose of antibody or ADC.

Figure 2 Binding of hz1613F12 and hz1613F12-24 DAR4 and DAR2 to SN12C human renal tumor cells as determined by FACS analysis. Data represent the mean intensity of fluorescence obtained over a range dose of antibody or ADC.

ELISA

Figure 3 Binding of hz1613F12 and of hz1613F12-24 DAR4 and hz1613F12-24 DAR2 on rhAxl-Fc immobilized protein as determined by ELISA. Data represent the optical densities obtained over a range dose of the tested antibodies. Data were analysed using Prism application.

Figure 3 Binding of hz1613F12 and of hz1613F12-24 DAR4 and hz1613F12-24 DAR2 on rhAxl-Fc immobilized protein as determined by ELISA. Data represent the optical densities obtained over a range dose of the tested antibodies. Data were analysed using Prism application.

FC

Figure 4 Binding of hz1613F12 and hz1613F12-33 DAR4 to SN12C human renal tumor cells as determined by FACS analysis. Data represent the mean intensity of fluorescence obtained over a range dose of antibody or ADC.

Figure 4 Binding of hz1613F12 and hz1613F12-33 DAR4 to SN12C human renal tumor cells as determined by FACS analysis. Data represent the mean intensity of fluorescence obtained over a range dose of antibody or ADC.

ELISA

Figure 5 Binding of hz1613F12 and of hz1613F12-33 DAR4 on rhAxl-Fc immobilized protein as determined by ELISA. Data represent the optical densities obtained over a range dose of the tested antibodies. Data were analysed using Prism application.

Figure 5 Binding of hz1613F12 and of hz1613F12-33 DAR4 on rhAxl-Fc immobilized protein as determined by ELISA. Data represent the optical densities obtained over a range dose of the tested antibodies. Data were analysed using Prism application.

Cyt

Figure 6 Concentration response cytotoxicity curves for hz1613F12-24 in Axl+SN12C (●) and in the control Axl- MCF7 (□) cell lines. A-at Day 3, B-at Day 6. Values of the EC₅₀ concentration was determined using Prism application with the regression analysis for each curve.

Figure 6 Concentration response cytotoxicity curves for hz1613F12-24 in Axl+SN12C (●) and in the control Axl- MCF7 (□) cell lines. A-at Day 3, B-at Day 6. Values of the EC₅₀ concentration was determined using Prism application with the regression analysis for each curve.


Specifications

  • Host Species
  • Human
  • Type
  • Humanized antibody
  • Specificity
  • Human
  • Clone
  • Hz1613F12
  • Applications
  • ELISA, FC, Cyt
  • Related Disease
  • Breast cancer, NSCLC, Pancreas cancer, Lung cancer, Renal cancer

Applications

  • Application Notes
  • This antibody as been tested for use in Enzyme-linked Immunosorbent Assay, Flow Cytometry and Cytotoxicity.

Target

  • Alternative Names
  • AXL; AXL receptor tyrosine kinase; ARK; UFO; JTK11; Tyro7

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Clone Hz1613F12"

See other products for "AXL"

Humanized Antibody

CAT Product Name Application Type
TAB-0139CL Anti-Human AXL Recombinant Antibody (hzl613F12-24 DAR2) ELISA, IF, FC, Inhib, ICFC Humanized Antibody
TAB-1098CL Anti-Human AXL Recombinant Antibody (Humanized 11B7) ELISA, FuncS Humanized antibody
TAB-1099CL Anti-Human AXL Recombinant Antibody (Humanized 11D5) ELISA Humanized antibody
TAB-0139CL-S(P) Anti-Human AXL Recombinant Antibody scFv Fragment (hzl613F12-24 DAR2) ELISA, IF, FC, Inhib, ICFC Humanized Antibody
TAB-0140CL-S(P) Anti-Human AXL Recombinant Antibody scFv Fragment (hzl613F12-33 DAR4) ELISA, IF, FC, Inhib, ICFC Humanized Antibody

Rabbit Monoclonal Antibody

CAT Product Name Application Type
MOR-3970 Hi-Affi™ Rabbit Anti-AXL Recombinant Antibody (clone SI30DS) ELISA Rabbit IgG

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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