+ Filter
Loading...
Custom Services order now ship next day

Anti-AXL Recombinant Antibody Products

At Creative Biolabs, we take pride in providing cutting-edge AXL-targeted recombinant antibodies to researchers worldwide. With a dedication to excellence and continuous innovation, we support your scientific endeavors by providing superior products and exceptional technical support. Collaborate with us to propel your research forward and achieve ground-breaking results efficiently.

AXL: An Attractive Target in Cancer Therapy

AXL, a receptor tyrosine kinase within the TAM family that includes TYRO3 and MERTK, plays a crucial role in normal tissues by aiding the clearance of apoptotic cells and moderating TLR-mediated inflammatory responses and natural killer cell activity. Recently, AXL has been identified as a significant driver of immune evasion and drug resistance in cancer cells, leading to the progression of aggressive cancers such as triple-negative breast cancer (TNBC), acute myeloid leukemia (AML), non-small-cell lung cancer (NSCLC), pancreatic cancer, and ovarian cancer. This makes AXL a promising target for the development of new cancer therapies.

Anti-AXL Recombinant Antibody Products

Our advanced platforms enable our experienced research team to develop and offer a range of innovative and high-quality recombinant antibody products. We ensure robust quality control and provide top-notch technical support to empower our customers to apply our products to their meaningful projects with exceptional value.

Cat. No. Product Name Target Species Host Species Applications
HPAB-M0416-YC Human Anti-AXL Recombinant Antibody Human Human IgG ELISA
MOB-2240z Mouse Anti-AXL Recombinant Antibody (clone 23F11) Human Mouse IgG1 WB, ELISA, IF, IHC
HPAB-0110-LS Mouse Anti-AXL Recombinant Antibody Human Mouse IgG WB, Agonist, ELISA, FC, SPR, FuncS
TAB-1086CLV Human Anti-AXL Recombinant Antibody Human Chimeric (mouse/human) IgG1, κ ELISA
TAB-1099CL Anti-Human AXL Recombinant Antibody (Humanized 11D5) Human Humanized antibody ELISA

Creative Quality Control

We are deeply committed to the biopharmaceutical community and strive to provide unwavering support for research and development. Our focus on superior product quality and unmatched customer support is evident in everything we do. We are committed to achieving total customer satisfaction through our rigorous and thorough quality control system. Our products are engineered to exceed industry standards, enabling the efficient development of medications and delivering exceptional value to our customers.

Fig.1 SDS-PAGE analysis. (Creative Biolabs Original)Fig.1 Anti-AXL Recombinant Antibody in SDS-PAGE.
(Cat# HPAB-0110-LS, Creative Biolabs).

Fig.2 WB analysis. (Creative Biolabs Original)Fig.2 Anti-AXL Recombinant Antibody in WB.
(Cat# HPAB-0110-LS, Creative Biolabs).

Fig.3 HPLC analysis. (Creative Biolabs Original)Fig.3 Anti-AXL Recombinant Antibody in HPLC.
(Cat# HPAB-M0416-YC, Creative Biolabs).

Fig.4 SDS-PAGE analysis. (Creative Biolabs Original)Fig.4 Anti-AXL Recombinant Antibody in SDS-PAGE.
(Cat# HPAB-M0416-YC, Creative Biolabs).

Customer Reviews

Excellent
An***s
Mouse Anti-AXL Recombinant Antibody (clone 23F11) (CAT#: MOB-2240z)
I purchased the anti-AXL recombinant antibody from Creative Biolabs for use in ELISA experiments with human serum samples. This antibody demonstrated excellent specificity for human AXL. Additionally, when I used this antibody in Western Blot experiments, it exhibited outstanding sensitivity and specificity in detecting AXL protein expression levels.
19/Sep/2023 5 Likes
Excellent
Re***a
Mouse Anti-AXL Recombinant Antibody (clone 23F11) (CAT#: MOB-2240z)
I recently used the anti-AXL recombinant antibody from Creative Biolabs for my IHC assays on human tissue samples. The antibody showed outstanding specificity and sensitivity in identifying AXL expression, providing clear and consistent results. It greatly improved the accuracy of my research.
5/Nov/2023 3 Likes
Excellent
Pa***o
Anti-Human AXL Recombinant Antibody (Humanized 11D5) (CAT#: TAB-1099CL)
I've used the anti-AXL recombinant antibody in my recent ELISA assays and was pleased with its performance. The antibody displayed remarkable specificity, making it easy to accurately detect AXL in my samples, with consistent and reliable results throughout my experiments. The reproducibility was top-notch, bolstering confidence in my data. I highly recommend this antibody for researchers in cancer biology and signal transduction studies.
26/Apr/2024 2 Likes

Anti-AXL Recombinant Antibody Production

We offer an advanced serum-free mammalian cell expression system that covers every step from gene synthesis to the scalable production of high-quality anti-AXL recombinant antibodies. With over five years of expertise in optimizing these processes, we deliver rapid and cost-effective solutions designed to meet fluctuating antibody supply needs within a short turnaround time.

Featured Anti-AXL Recombinant Antibody Production Platforms

Fig.5 Milligram-scale. (Creative Biolabs Original)Fig.5 Milligram-scale anti-AXL recombinant antibody production.

Fig.6 Gram-scale. (Creative Biolabs Original)Fig.6 Gram-scale anti-AXL recombinant antibody production.

Anti-AXL Recombinant Antibody Modalities

At Creative Biolabs, we specialize in providing cutting-edge recombinant antibody solutions tailored to the unique requirements of the research community. Our portfolio of anti-AXL recombinant antibodies encompasses a range of formats, including full-length, Fab, scFv, and more. Leveraging our comprehensive antibody engineering expertise and years of experience, we are devoted to providing tailored solutions that propel your research goals forward.

Fig.7 AXL antibody production and modalities. (Creative Biolabs Original)Fig.7 Full-Length Anti-AXL Recombinant Antibody Production and Modalities

Alternative Names

AZF; AZFA; SP3; AZF1; ARK; JTK11; Tyro7; UFO; AXL receptor tyrosine kinase.

Background

The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.
Protein class

Disease related genes, Enzymes, FDA approved drug targets, Metabolic proteins, Plasma proteins

Predicted location

Membrane

Single cell type specificity

Cell type enhanced (Sertoli cells, Kupffer cells, Langerhans cells, Smooth muscle cells, Fibroblasts, Prostatic glandular cells)

Immune cell specificity

Immune cell enhanced (plasmacytoid DC, NK-cell)

Cell line specificity

Cell line enhanced (fHDF/TERT166, U-251 MG)

Interaction

Heterodimer and heterotetramer with ligand GAS6. Interacts with CBL, GRB2, LCK, NCK2, PIK3R1, PIK3R2, PIK3R3, PLCG1, SOCS1 and TNS2. Part of a complex including AXL, TNK2 and GRB2, in which GRB2 promotes AXL recruitment by TNK2.

Molecular function

Host cell receptor for virus entry, Kinase, Receptor, Transferase, Tyrosine-protein kinase

More Types Infomation

Drug Information Targeting AXL

Table 1. AXL-targeted drug information.

Company Highest Phase Classification Condition
3D Medicines
Aravive (Originator)
Aravive Biologics (Aravive)
Phase III Fc Fusion Proteins
Polypeptides, from 41 AA
Cancer
Cancer, bladder (urothelial carcinoma)
Cancer, breast
Cancer, fallopian tube
Cancer, kidney (renal cell carcinoma, clear cell)
Cancer, ovary
Cancer, pancreas
Cancer, pancreas (adenocarcinoma)
Cancer, solid tumor
Carcinoma, primary peritoneal (ovarian)
Fibrosis
IgA nephropathy
Infection, Zika virus
Myeloid leukemia
BioAtla (Originator) Phase II Antibodies
Antibody-Drug Conjugates (ADCs)
Auristatins
Cancer Immunotherapy
Cancer, lung (non-small cell) (NSCLC)
Cancer, ovary
Cancer, pancreas
Cancer, pancreas (ductal adenocarcinoma)
Cancer, prostate (castration-resistant)
Cancer, solid tumor
Osteosarcoma
Sarcoma
Soft tissue sarcoma
EXUMA Biotech (Originator)
Shanghai PerHum Therapeutics
Sinobioway Sunterra Biotechnology (Shanghai PerHum Therapeutics)
Phase I/II Cancer Immunotherapy
Chimeric Antigen Receptor-Modified T Cells (CAR T Cells)
Cancer, kidney (renal cell carcinoma), metastatic
Sarcoma
Arcus Biosciences (Originator) Phase I Chemosensitizers Cancer
Cancer, lung (non-small cell) (NSCLC)
BerGenBio (Originator)
Bergen Teknologioverfoering (Originator)
Phase I Cancer Immunotherapy
Humanized Monoclonal Antibodies
Cancer
ADC Therapeutics (Originator)
Overland ADCT BioPharma
Phase I Antibody-Drug Conjugates (ADCs)
Cancer Immunotherapy
Humanized Monoclonal Antibodies
Pyrrolobenzodiazepines
Acute lymphocytic leukemia
Cancer, breast
Cancer, esophagus
Cancer, head and neck
Cancer, lung (non-small cell) (NSCLC)
Cancer, ovary
Cancer, pancreas
Cancer, solid tumor
Cancer, stomach
Mesothelioma, malignant
Non-Hodgkin lymphoma
Soft tissue sarcoma
SSY Group (Originator) IND Filed Cancer, liver
Cancer, lung
Cancer, prostate
Cancer, solid tumor
Cancer, stomach
Universitair Ziekenhuis Brussel (Originator)
Vrije Universiteit Brussel (VUB) (Originator)
Preclinical Cancer Immunotherapy
Fc Fusion Proteins
Nuclear Imaging Agents
Polypeptides, from 41 AA
Radioimmunoconjugates
Radiopharmaceuticals
Single-Domain Antibodies
Technetium Complexes
Acute myeloid leukemia

(Disclaimer: The information in this table is just for knowledge sharing and not for marketing or sales purposes.)

Please feel free to reach out to us at your earliest convenience if you would like to learn more about our anti-AXL recombinant antibody products.

More Infomation

Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

For Research Use Only. Not For Clinical Use.

  • 0
  • 0
Cart
    Go to compare

    Go to compare