Recombinant Anti-AXL (AA 1-134 x AA 222-234) Biparatopic Antibody, Tandem scFv (CAT#: VS-0525-YC20)

• Host Animal 1
• Human

• Host Animal 2
• Human

• Specificity
• Human AXL

• Species Reactivity
• Human, Mouse

• Type
• Tandem scFv

• Valency
• 1 + 1

• Epitope 1
• aa 1-134 of human Axl.

• Epitope 2
• aa 222-234 of human Axl.

• Purity
• >90%

• Purification
• Affinity purified

• Applications
• Block, ELISA, FC, IHC, SPR, WB

• Concentration
• Lot specific

• Buffer
• PBS, pH 7.4

• Preservative
• No preservatives

• Storage
• Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid freeze-thaw cycles.

• Long Name
• AXL Receptor Tyrosine Kinase

• Introduction
• The protein encoded by this gene is a member of the Tyro3-Axl-Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin-like motifs at the N-terminal, followed by two fibronectin type-III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K-dependent protein growth arrest-specific 6 (Gas6). This gene may be involved in several cellular functions including growth, migration, aggregation and anti-inflammation in multiple cell types. Alternative splicing results in multiple transcript variants of this gene.

• Alternative Names
• ARK; UFO; JTK11; Tyro7

• Gene ID
• 558

• UniProt ID
• P30530

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