Rabbit Anti-B2M Recombinant Antibody (VS3-CJ1081) (CAT#: VS3-CJ1081)
This product is a rabbit antibody that recognizes human, mouse, and rat B2M.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6361/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6361/if_selected.jpg
Figure 2 IF staining of human cell line A-431
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2572/if_selected.jpg
(Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane, cytosol & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2572/if_selected.jpg
Figure 3 Spleen
(High expression in spleen)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6361/18752_B_7_4_val_selected.jpg
(High expression in spleen)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/6361/18752_B_7_4_val_selected.jpg
Figure 4 Bone marrow
(Hematopoietic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2572/6948_B_6_4.jpg
(Hematopoietic cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2572/6948_B_6_4.jpg
Figure 5 Lymph node
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2572/6948_A_8_8.jpg
(Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2572/6948_A_8_8.jpg
Figure 6 Cerebral cortex
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2572/6948_B_8_5.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2572/6948_B_8_5.jpg
Figure 7 Kidney
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Collecting ducts Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2572/6948_A_8_5.jpg
(Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Collecting ducts Staining: Low Intensity: Moderate Quantity: <25%)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2572/6948_A_8_5.jpg
Figure 8 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166710-B2M
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000166710-B2M
Specifications
- Immunogen
- Recombinant protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse, Rat B2M
- Species Reactivity
- Human, Mouse, Rat
- Applications
- WB, ICC, IP
- Conjugate
- Unconjugated
Product Property
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Format
- Liquid
- Buffer
- 40% Glycerol, 1% BSA, TBS, pH7.4.
- Preservative
- 0.05% Sodium Azide
- Storage
- Store at 4°C for short term. Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Western Blot, Immunocytochemistry, Immunoprecipitation.
Target
- Alternative Names
- IMD43
- Gene ID
- 567
- UniProt ID
- P61769
- Sequence Similarities
- Belongs to the beta-2-microglobulin family.
- Cellular Localization
- Amyloid, MHC I, Secreted
- Post Translation Modifications
- Glycation of Ile-21 is observed in long-term hemodialysis patients.
- Protein Refseq
- NP_004039.1
- Function
- Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553).
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "B2M"
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1431z-F(E) | Recombinant Anti-Human B2M Antibody Fab Fragment | Neut, WB, FuncS | Fab |
| HPAB-0130-FY-F(E) | Human Anti-B2M Recombinant Antibody (clone B2M-1D8); Fab Fragment | ELISA | Humanized Fab |
| HPAB-0131-FY-F(E) | Human Anti-B2M Recombinant Antibody (clone B2M-2F6); Fab Fragment | ELISA | Humanized Fab |
| HPAB-0350-FY-F(E) | Mouse Anti-B2M Recombinant Antibody (clone FY-007); Fab Fragment | ELISA | Mouse Fab |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1431z-S(P) | Recombinant Anti-Human B2M Antibody scFv Fragment | ELISA, WB, Neut, FuncS | scFv |
| HPAB-0130-FY-S(P) | Human Anti-B2M Recombinant Antibody (clone B2M-1D8); scFv Fragment | ELISA | Humanized scFv |
| HPAB-0131-FY-S(P) | Human Anti-B2M Recombinant Antibody (clone B2M-2F6); scFv Fragment | ELISA | Humanized scFv |
| HPAB-0350-FY-S(P) | Mouse Anti-B2M Recombinant Antibody (clone FY-007); scFv Fragment | ELISA | Mouse scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PNBL-076 | Recombinant Anti-B2M VHH Single Domain Antibody (Nb24) | FACS, BL | Llama VHH |
| HPAB-A1221-YJ | Camelid Anti-B2M Recombinant Antibody (clone CBB501) | ELISA | Camelid VHH |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0078MZ | Mouse Anti-B2M Recombinant Antibody (clone C2G8) | FC, IHC | Mouse IgG2a |
| MOB-1592MZ | Mouse Anti-B2M Recombinant Antibody (clone IZC443-02) | ELISA | Mouse IgG1 |
| MRO-0168-CN | Rabbit Anti-B2M Recombinant Antibody (clone CBACN-066) | WB, IF, IP | Rabbit IgG |
| VS3-QX95 | Mouse Anti-B2M Recombinant Antibody (clone 5G12-E9-E1) | WB, IHC, ICC, FC, ELISA | Mouse IgG2a |
| VS3-QX96 | Mouse Anti-B2M Recombinant Antibody (clone 467CT12.3.1) | WB | Mouse IgG1 |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-1010MZ | Chicken Anti-beta-2 Microglobulin Polyclonal IgY | WB | Chicken antibody |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-034CQ | Mouse Anti-B2M Recombinant Antibody (clone YTH470.5) | FC, Block | Mouse IgG1, κ |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-0312 | Hi-Affi™ Rabbit Anti-B2M Recombinant Antibody (clone DS312AB) | ELISA | Rabbit IgG |
| MOR-3971 | Hi-Affi™ Rabbit Anti-B2M Recombinant Antibody (clone SI31DS) | IHC-P | Rabbit IgG |
| MOR-4538 | Hi-Affi™ Rabbit Anti-B2M Recombinant Antibody (clone TH46DS) | WB | Rabbit IgG |
MHC Tetramer for Cancer
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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