This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant humanized (from mouse) antibody expressed in CHO binding to human CD40 ligand. It was a humanized monoclonal antibody and an immunosuppressive drug.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
Anti-Human CD40 ligand Recombinant Antibody (Toralizumab)Recombinant humanized (from mouse) antibody expressed in CHO binding to human CD40 ligand. Toralizumab was a humanized monoclonal antibody and an immunosuppressive drug. Possible indications included treatment of antibody-mediated disorders (immune thrombocytopenic purpura, lupus nephritis, rheumatoid arthritis), T-cell-mediated diseases (multiple sclerosis, Crohn's disease, and transplantations such as solid organ transplantation, pancreatic islet cell transplantation, and corneal transplantation), and B-cell malignancies such as CLL/small lymphocytic lymphoma, follicular cell lymphoma grade I or II, marginal zone lymphoma, mantle cell lymphoma, MALT lymphoma, Waldenstrom's macroglobulinemia, monocytoid B-cell lymphoma; relapsed/refractory Hodgkin's disease).
DrugMonitor™ Anti-Toralizumab Antibody (VS-1224-YC1223)Toralizumab (IDEC 131) was a humanized monoclonal antibody and immunosuppressive drug. The DrugMonitor™ Anti-Toralizumab Antibody (VS-1224-YC1223) is an anti-drug antibody (ADA) against Toralizumab. This drug-based antibody is raised in mice immunized with the Toralizumab. The anti-Toralizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Toralizumab in samples.
Select a product category from the dropdown menu below to view related products.
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-1071z | Mouse Anti-CD40LG Recombinant Antibody (clone 18C1) | ELISA, FC, FuncS, ICC, IF | Mouse IgG1 |
PABW-020 | Human Anti-CD40LG Recombinant Antibody (PABW-020) | Neut | Human IgG1, κ |
FAMAB-0135YC | Hamster Anti-CD40LG Recombinant Antibody (clone mr-1) | ELISA | Hamster IgG |
MRO-0304-CN | Rabbit Anti-CD40LG Recombinant Antibody (clone JM11-34) | WB, IF, IHC, FC | Rabbit IgG |
VS3-CJ861 | Mouse Anti-CD40LG Recombinant Antibody (clone M91) | IF, FC | Mouse IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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