Mouse Anti-CD59 Recombinant Antibody (clone 193-27)

Name: Mouse Anti-CD59 Recombinant Antibody (clone 193-27)
SKU: VS11-QX41
Rating: 5 (1 reviews)

CAT#: VS11-QX41

This product is a recombinant mouse antibody that is specific for human CD59. This antibody can be used for the following applications: FC, IHC, IF.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line A-431

Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus & vesicles.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26494/279_B8_2_selected.jpg

Subcellular Location Figure 2 IHC staining of human urinary bladder

Immunohistochemical staining of human urinary bladder shows distinct membranous positivity in urothelial cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26494/ihc_selected.jpg

Subcellular Location Figure 3 IF staining of human cell line PC-3

Immunofluorescent staining of human cell line PC-3 shows localization to the vesicles.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26494/1432_F1_2_blue_red_green.jpg

Subcellular Location Figure 4 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus & cytosol.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26494/280_B8_1_blue_red_green.jpg

Normal Tissue Figure 5 Cerebral cortex

Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26494/55053_B_8_5.jpg

Normal Tissue Figure 6 Colon

Endothelial cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
Peripheral nerve/ganglion
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26494/55159_A_7_3.jpg

Normal Tissue Figure 7 Urinary bladder

Urothelial cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/26494/55159_A_6_5.jpg

RNA Expression Figure 8 RNA cell line category: Cell line enhanced (TIME, U-2197)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000085063-CD59

❮

❯

Specifications

Immunogen
Stimulated human leukocytes

Host Species
Mouse

Derivation
Mouse

Type
Mouse IgM, κ

Specificity
Human CD59

Species Reactivity
Human

Clone
193-27

Applications
FC, IHC, IF

Conjugate
Unconjugated

Product Property

Clonality
Monoclonal

Purification
Affinity Purified

Purity
>95% as determined by SDS-PAGE

Concentration
1 mg/mL (Please refer to the vial label for the specific concentration.)

Buffer
0.2 μm filtered solution in PBS

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Shipping
Shipped at 4°C.

Target

Alternative Names
CD59 Molecule (CD59 Blood Group); CD59 Antigen P18-20 (Antigen Identified By Monoclonal Antibodies 16.3A5, EJ16, EJ30, EL32 And G344); CD59 Molecule, Complement Regulatory Protein; Membrane Attack Complex Inhibition Factor; Membrane Inhibitor Of Reactive Lysis; 20 KDa Homologous Restriction Factor; MEM43 Antigen; 1F5 Antigen; Protectin; HRF-20; MAC-IP; MIC11; MSK21; HRF20; MACIF; MIN1; MIN2; MIN3; MIRL; Surface Anitgen Recognized By Monoclonal Antibody 16.3A5

Gene ID
966

UniProt ID
P13987

Long Name
CD59 glycoprotein

Cellular Localization
Golgi apparatus, Vesicles

Function
Potent inhibitor of the complement membrane attack complex (MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for VS11-QX41. Click the button above to contact us or submit your feedback about this product.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS11-QX41.pdf

MSDS

MSDS - VS11-QX41.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

Immunohistochemistry (IHC)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

Isotype Control

CAT
Product Name

Recommended Dilution Buffer

CAT
Product Name

Secondary Antibody

CAT
Product Name

See other products for "CD59"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
MOB-1088z	Mouse Anti-CD59 Recombinant Antibody (clone 18C6)	FC, IF, FuncS	Mouse IgM, κ
MOB-0520CT	Recombinant Mouse anti-Human CD59 Monoclonal antibody (2G6)	FC
ZG-0208U	Mouse Anti-CD59 Recombinant Antibody (clone 2E11B6)	ELISA, WB, IHC	Mouse IgG1
VS3-WK768	Mouse Anti-CD59 Recombinant Antibody (clone OV9A2)	FC, IF	Mouse IgG1
VS3-XY382	Mouse Anti-CD59 Recombinant Antibody (clone 8D2B8)	ELISA, WB, IHC, FC, ICC	Mouse IgG1

CAT	Product Name	Application	Type
TAB-319LC	Human Anti-CD59 Recombinant Antibody (TAB-319LC)	ELISA, FC, Inhib	Human IgG1
TAB-319LC-S(P)	Human Anti-CD59 Recombinant Antibody; scFv Fragment (TAB-319LC-S(P))	ELISA	Human scFv
TAB-319LC-F(E)	Human Anti-CD59 Recombinant Antibody; Fab Fragment (TAB-319LC-F(E))	ELISA	Human Fab

CAT	Product Name	Application	Type
TAB-321LC	Anti-Human CD59 Recombinant Antibody ((ch)AR36A36.11.1)	ELISA, FuncS, WB	Chimeric antibody (mouse/human)
TAB-321LC-S(P)	Anti-Human CD59 Recombinant Antibody scFv Fragment ((ch)AR36A36.11.1)	WB, ELISA	Chimeric antibody (mouse/human)
TAB-321LC-F(E)	Anti-Human CD59 Recombinant Antibody Fab Fragment ((ch)AR36A36.11.1)	WB, ELISA	Chimeric antibody (mouse/human)

CAT	Product Name	Application	Type
TAB-317LC-S(P)	Mouse Anti-CD59 Recombinant Antibody; scFv Fragment (TAB-317LC-S(P))	WB, ELISA	Mouse scFv
TAB-318LC-S(P)	Anti-Human CD59 Recombinant Antibody scFv Fragment (1E8)	FC, ELISA
TAB-320LC-S(P)	Anti-Human CD59 Recombinant Antibody scFv Fragment (AR36A36.11.1)	WB, ELISA
TAB-317LC-F(E)	Mouse Anti-CD59 Recombinant Antibody; Fab Fragment (TAB-317LC-F(E))	WB, ELISA	Mouse Fab
TAB-318LC-F(E)	Anti-Human CD59 Recombinant Antibody Fab Fragment (1E8)	FC, ELISA

CAT	Product Name	Application	Type
TAB-322LC-S(P)	Anti-Human CD59 Recombinant Antibody scFv Fragment (HV3/KV3 )	WB, ELISA	Humanized antibody
TAB-323LC-S(P)	Anti-Human CD59 Recombinant Antibody scFv Fragment (HV2/KV3)	WB, ELISA	Humanized antibody
TAB-324LC-S(P)	Anti-Human CD59 Recombinant Antibody scFv Fragment (HV2/KV4)	WB, ELISA	Humanized antibody
TAB-322LC-F(E)	Anti-Human CD59 Recombinant Antibody Fab Fragment (HV3/KV3 )	WB, ELISA	Humanized antibody
TAB-323LC-F(E)	Anti-Human CD59 Recombinant Antibody Fab Fragment (HV2/KV3)	WB, ELISA	Humanized antibody

CAT	Product Name	Application	Type
NEUT-397CQ	Mouse Anti-CD59 Recombinant Antibody (clone MEM-43)	Neut, FC, IHC, IHC-P, IP, CyTOF®	Mouse IgG2a

CAT	Product Name	Application	Type
NEUT-398CQ	Rat Anti-CD59 Recombinant Antibody (clone YTH53.1)	Block, FC, ICC, IF, IHC-Fr, IHC-P, WB, FuncS	Rat IgG2b

CAT	Product Name	Application	Type
MOR-0572	Hi-Affi™ Rabbit Anti-CD59 Recombinant Antibody (clone DS572AB)	WB, IHC	Rabbit IgG

CAT	Product Name	Application	Type
MHC-LC1953	PE-A2/Human CD59 (SLSEKTVLL) MHC Tetramer	FCM
MHC-LC1980	PE-A*02:01/Human CD59 (SLSEKTVLL) MHC Tetramer	FCM

CAT	Product Name	Application	Type
VS-0724-YC1325	AbPlus™ Anti-Cd59 Magnetic Beads (VS-0724-YC1325)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0125-FY58	Human Anti-CD59 (clone 1E8) scFv-Fc Chimera	ELISA, FC, CDC	Human IgG1, scFv-Fc

CAT	Product Name	Application	Type
VS-0225-XY62	CytoStream™ Mouse Anti-CD59 Recombinant Antibody (clone MEM-43)	FC	Mouse IgG2a, kappa

CAT	Product Name	Application
VS-0325-XY368	Anti-CD59 Immunohistochemistry Kit	IHC
VS-0525-XY1204	Anti-Mouse CD59 Immunohistochemistry Kit	IHC
VS-0525-XY1203	Anti-Human CD59 Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0425-YC183	Recombinant Anti-CD59 Vesicular Antibody, EV Displayed (VS-0425-YC183)	ELISA, FC, Cell-uptake

Specific Inquiry

Size:

Conjugation:

Endotoxin:

Purity:

Formats:

Isotype Switching:

Fc Engineering:

Modalities:

Add to compare

Request
Custom Production

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Figure 3 Human Anti-MS4A1 Recombinant Antibody (TAB-772) in SDS-PAGE

Human Anti-MS4A1 Recombinant Antibody (TAB-772) (CAT# TAB-772)
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC

Figure 2 Anti-Human CD25 Antibody (TAB-023) in HPLC

Anti-Human CD25 Recombinant Antibody (Daclizumab) (CAT# TAB-023)
Application: ELISA, Neut, IF, IP, FC, FuncS

Figure 5 Anti-Human folate receptor 1 Antibody (TAB-113) in SEC-HPLC

Anti-Human folate receptor 1 Recombinant Antibody (TAB-113) (CAT# TAB-113)
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC

Figure 3 Anti-ErbB2 Antibody (TAB-053) in Dot Blot

Anti-Human ERBB2 Recombinant Antibody (TAB-053) (CAT# TAB-053)
Application: FuncS, IF, Neut, ELISA, FC, IP, WB

Figure 2 Humanized Anti-CD28 Recombinant Antibody (TAB-H46) in HPLC

Humanized Anti-CD28 Recombinant Antibody (clone Lulizumab) (CAT# TAB-H46)
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC

Figure 4 Anti-Human IAV HA Recombinant Antibody (TAB-705)-Fc silenced in ELISA

Anti-αvβ3 Integrin Recombinant Antibody (TAB-705) (CAT# TAB-705)
Application: FC, IP, ELISA, Neut, FuncS, IF, IHC

Figure 3 Anti-Human CTGF Recombinant Antibody (TAB-194CL) in ELISA.

Anti-Human CTGF Recombinant Antibody (TAB-194CL) (CAT# TAB-194CL)
Application: WB, IHC, IF

Figure 4 Afuco™ Anti-Human LRRC15 ADCC Recombinant Antibody, ADCC Enhanced (AFC-480CL) in Lectin ELISA

Afuco™ Anti-Human LRRC15 ADCC Recombinant Antibody, ADCC Enhanced (CAT# AFC-480CL)
Application:

Figure 2 Recombinant Anti-HIV env Antibody (PABL-179) in HPLC

Human Anti-HIV-1 gp160 Recombinant Antibody (clone PGT128) (CAT# PABL-179)
Application: WB, ELISA, FuncS

Figure 1 Recombinant Human Anti-RSV Antibody (PABL-321) in SDS-PAGE

Recombinant Human Anti-RSV Antibody (AM14) (CAT# PABL-321)
Application: WB, ELISA, Neut, FuncS

Figure 1 Anti-Human CD200R Protein Antibody in ELISA

Human Anti-CD200R1 Recombinant Antibody (clone OX108) (CAT# PABC-020)
Application: WB, FuncS

Figure 4 Mouse Anti-AAV VP1 Recombinant Antibody (PABL-390) in ELISA

Recombinant Mouse Anti-AAV VP1 Antibody (A20) (CAT# PABL-390)
Application: ICC, IF

Figure 2 Anti-Human DEspR Recombinant Antibody (TAB-190MZ) in HPLC

Anti-Human DEspR Recombinant Antibody (TAB-190MZ) (CAT# TAB-190MZ)
Application: FC, FuncS, Inhib

Figure 2 Anti-Human TEM7R Recombinant Antibody (TAB-577CT) in HPLC

Human Anti-PLXDC2 Recombinant Antibody (TAB-577CT) (CAT# TAB-577CT)
Application: ELISA, FC, IHC, IF

Figure 3 Human Anti-APLNR Recombinant Antibody (TAB-0938CLV) in FACS

Human Anti-APLNR Recombinant Antibody (TAB-0938CLV) (CAT# TAB-0938CLV)
Application: ELISA

Figure 5 Mouse Anti-ADRB1 Recombinant Antibody (clone DSM ACC3121) (HPAB-0273-YC) in DB

Mouse Anti-ADRB1 Recombinant Antibody (clone DSM ACC3121) (CAT# HPAB-0273-YC)
Application: ELISA

Figure 2 Human Anti-SLC30A8 Recombinant Antibody (clone C22) (HPAB-0040-CN) in SDS-PAGE

Human Anti-SLC30A8 Recombinant Antibody (clone C22) (CAT# HPAB-0040-CN)
Application: ELISA, WB, IHC

Figure 2 Human Anti-CA19-9 Recombinant Antibody; Fab Fragment (HPAB-0038-WJ-F(E)) in HPLC

Human Anti-CA19-9 Recombinant Antibody Fab Fragment (HPAB-0038-WJ-F(E)) (CAT# HPAB-0038-WJ-F(E))
Application: ELISA

Figure 6 Recombinant Mouse Anti-EBV gH/gL Antibody (CL59) (PABC-523) in Dot Blot

Mouse Anti-EBV gH/gL Recombinant Antibody (clone CL59) (CAT# PABC-523)
Application: ELISA, FC, Neut, Inhib

Figure 2 Mouse Anti-FSTL3 Recombinant Antibody (HPAB-N0094-YC) in HPLC

Mouse Anti-FSTL3 Recombinant Antibody (HPAB-N0094-YC) (CAT# HPAB-N0094-YC)
Application: Neut, WB

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.