Anti-FAP (clone ESC14) Recombinant Antibody Coupled Liposome (VS-1024-FY270)
CAT#: VS-1024-FY270
Anti-FAP liposomes represent a novel approach in targeted drug delivery systems that specifically aim at fibroblast activation protein (FAP), which is commonly associated with various tumors. By precisely targeting FAP, these liposomes enhance the therapeutic effects of the encapsulated drugs, potentially leading to more effective treatment outcomes with fewer side effects. The design of anti-FAP liposomes allows for a higher accumulation of therapeutic agents in tumor tissues, improving the localization and minimizing systemic exposure. Overall, this targeted strategy holds great promise for advancing cancer treatment by leveraging the unique characteristics of the tumor microenvironment.
Gene Expression
Normal Tissue
Figure 1 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
Glandular cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_9_3.jpg
Normal Tissue
Figure 2 Liver
Cholangiocytes
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_8_4.jpg
Normal Tissue
Figure 3 Kidney
Cells in tubules
Staining:Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_7_5.jpg
Normal Tissue
Figure 4 Testis
Cells in seminiferous ducts
Staining:High
Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_A_4_6.jpg
Normal Tissue
Figure 5 Smooth muscle
Smooth muscle cells
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/59739/134103_B_6_7.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, BJ hTERT+, hTERT-RPE1, U-138 MG)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000078098-FAP
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More Infomation
Specifications
- Potential Clinical Applications
- Metastatic fbrosarcoma
Product Composition
- Clone
- ESC14
- Antibody Type
- IgG1, kappa
- Antibody Host
- Human
- Antibody Reactivity
- Human
- Antibody Description
- This is a humanized monoclonal antibody that specifically targets fibroblast activation protein (FAP). It was developed for cancer treatment. The immunogen used in its creation is a synthetic peptide derived from human FAP, alpha.
Product Property
- Storage
- See in the COA
- Storage Shelf Time
- See in the COA
Target Information
- Target
- FAP
- Full Name
- Fibroblast Activation Protein Alpha
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Datasheet
MSDS
COA
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2277z | Mouse Anti-FAP Recombinant Antibody (clone 36B12) | FC, IF, IP | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-211 | Anti-Human FAP Recombinant Antibody (TAB-211) | ELISA, IP, FC, FuncS, Neut, IF, WB | IgG1 - kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-022WM | Human Anti-FAP Recombinant Antibody (TAB-022WM) | FC, ELISA | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-024WM | Human Anti-FAP Recombinant Antibody (TAB-024WM) | IHC, ELISA, FC, IF | Human IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-022WM-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (TAB-022WM-S(P)) | FC, ELISA | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-024WM-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (TAB-024WM-S(P)) | ELISA, FC, IF | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-022WM-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (TAB-022WM-F(E)) | FC, ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-150LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| Gly-151LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| Gly-152LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| Gly-153LC | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| Gly-153LC-1 | Recombinant Anti-Human FAP Antibody (Fc glycosylation/Non fucosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1515MZ | Recombinant Mouse Anti-Human FAP Antibody | WB | Mouse antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0170-CN | Human Anti-FAP Recombinant Antibody (HPAB-0170-CN) | ELISA, IF | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0171-CN | Mouse Anti-FAP Recombinant Antibody (HPAB-0171-CN) | ELISA | Mouse IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0173-CN | Human Anti-FAP Recombinant Antibody (HPAB-0173-CN) | ELISA | Humanized IgG1, κ |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0170-CN-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0170-CN-S(P)) | ELISA, IF | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0171-CN-S(P) | Mouse Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0171-CN-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0173-CN-S(P) | Human Anti-FAP Recombinant Antibody; scFv Fragment (HPAB-0173-CN-S(P)) | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0175-CN-S(P) | Human Anti-FAP Recombinant Antibody (clone ESC14); scFv Fragment | ELISA, WB, FC, IHC, IP | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0176-CN-S(P) | Mouse Anti-FAP Recombinant Antibody (clone cF19); scFv Fragment | ELISA, FC, IHC, IP, IF | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0170-CN-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0170-CN-F(E)) | ELISA, IF | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0171-CN-F(E) | Mouse Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0171-CN-F(E)) | ELISA | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0173-CN-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0173-CN-F(E)) | ELISA | Humanized Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0175-CN-F(E) | Human Anti-FAP Recombinant Antibody (clone ESC14); Fab Fragment | ELISA, WB, FC, IHC, IP | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0172-CN-F(E) | Human Anti-FAP Recombinant Antibody; Fab Fragment (HPAB-0172-CN-F(E)) | ELISA, IHC | Chimeric (mouse/human) Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0619-CN | Recombinant Dromedary Anti-FAP Single Domain Antibody (HPAB-0619-CN) | ELISA | VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-211 | Afuco™ Anti-FAP ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-211) | ELISA, IP, FC, FuncS, Neut, IF | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0661 | PE-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0662 | APC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0663 | FITC-H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0664 | H-2Kb/Human FAP (SDYYFSWL) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-CN0665 | PE-A*02:01/Human FAP (GLFKCGIAV) MHC Tetramer | FCM, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY97 | AbPlus™ Anti-FAP Magnetic Beads (ESC14) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY118 | Human Anti-FAP (clone cF19) scFv-Fc Chimera | FC, IHC, IP | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY813 | Anti-FAP Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS13-YC379 | CytoStream™ Mouse Anti-FAP Recombinant Antibody (VS13-YC379) | IHC-P, FC, ELISA | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY2444 | Anti-Human FAP Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0625-YC109 | Recombinant Anti-FAP Eliminating Antibody, pH-Sensitive (VS-0625-YC109) | Antigen-Sweeping In Vivo. | Mouse IgG1 kappa |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0825-YC123 | SmartAb™ Recombinant Anti-FAP pH-dependent Antibody (VS-0825-YC123) | ELISA, IP, FC Neut, IF, WB | Human IgG1 kappa |
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