Human Anti-ICOS Antibody, mRNA

Name: Human Anti-ICOS Antibody, mRNA
SKU: TAB-378CL-mRNA
Rating: 5 (1 reviews)

CAT#: TAB-378CL-mRNA

This mRNA encodes a Human antibody against ICOS. It contains two mRNAs that encode for the heavy and light chains of the antibody.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line HEL

Immunofluorescent staining of human cell line HEL shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34865/1813_D4_33_selected.jpg

Subcellular Location Figure 2 IHC staining of human tonsil

Immunohistochemical staining of human tonsil shows strong cytoplasmic positivity in subsets of lymphoid cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/ihc_selected.jpg

Subcellular Location Figure 3 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/34865/1886_G11_2_blue_red_green.jpg

Normal Tissue Figure 4 Lymph node

Germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Non-germinal center cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/78503_A_9_8.jpg

Normal Tissue Figure 5 Tonsil

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/32575/78503_A_6_8.jpg

RNA Expression Figure 6 RNA cell line category: Group enriched (HEL, MOLT-4)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163600-ICOS

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Specifications

Host Species
Human

Specificity
Human ICOS

Species Reactivity
Human

Related Disease
Autoimmune Diseases

Product Property

Purity
>95%

Storage
Store at -20°C.

Target

Alternative Names
ICOS; inducible T-cell co-stimulator; AILIM; CD278; CVID1; inducible T-cell costimulator; inducible costimulator; activation-inducible lymphocyte immunomediatory molecule

Gene ID
29851

UniProt ID
Q53QY6

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Related Diseases

Primary Immunodeficiency

Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-378CL-mRNA.pdf

MSDS

MSDS - TAB-378CL-mRNA.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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