AbPlus™ Anti-IL6 Magnetic Beads (AS16)

CAT#: VS-0424-XY151

The AbPlus Anti-IL6 Magnetic Beads (AS16) is an innovative affinity resin which is bound with anti-IL6 specific antibody (AS16). The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of IL6 protein under native and denaturing conditions.

Gene Expression
Figure 1 IF staining of human cell line U-2 OS Figure 2 IHC staining of human duodenum Figure 3 Cerebral cortex Figure 4 Urinary bladder Figure 5 Lymph node Figure 6 RNA cell line category: Group enriched (BJ hTERT+, GAMG)

Specifications

  • Applications
  • Immunoprecipitation, Protein Purification
  • Matrix
  • Magrose bead (> 50 μmol/mL gel)
  • Bead Ligand
  • Anti-IL6 specific antibody (AS16)
  • Target
  • IL6
  • Target Species
  • Human
  • Antibody Clone
  • AS16
  • Bead Capacity
  • 20-30 mg/mL binding antibody
  • Bead size
  • 10-37 μm
  • Stability
  • pH 2-14
  • Format
  • 20% Suspension
  • Buffer
  • PBS, pH 7.4, with 1% BSA
  • Preservative
  • 0.03% Proclin 300
  • Storage
  • Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

  • Application Notes
  • The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

  • Introduction
  • This gene encodes a cytokine that functions in inflammation and the maturation of B cells. In addition, the encoded protein has been shown to be an endogenous pyrogen capable of inducing fever in people with autoimmune diseases or infections. The protein is primarily produced at sites of acute and chronic inflammation, where it is secreted into the serum and induces a transcriptional inflammatory response through interleukin 6 receptor, alpha. The functioning of this gene is implicated in a wide variety of inflammation-associated disease states, including suspectibility to diabetes mellitus and systemic juvenile rheumatoid arthritis.
  • Alternative Names
  • IL6; interleukin 6; HGF; HSF; BSF2; IL-6; IFNB2; interleukin-6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; interferon; beta 2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2; B-cell differentiation factor
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