Afuco™ Anti-IL6 ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-097) (CAT#: AFC-TAB-097)

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to IL6. It is a human monoclonal antibody designed for the treatment of rheumatoid arthritis.

Specific Inquiry
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  • Purity:
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  • Isotype Switching:
  • Fc Engineering:
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  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • Recombinant full length protein (Human).
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Applications
  • FC, IP, ELISA, Neut, FuncS, IF
  • Conjugate
  • Unconjugated
  • Generic Name
  • Sirukumab
  • Related Disease
  • Rheumatoid arthritis (RA) (Despite Methotrexate Therapy)

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • IL6; interleukin 6 (interferon, beta 2); IFNB2; interleukin-6; BSF2; HGF; HSF; IL 6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2;

Related Resources

  • Biosimilar Overview
  • Related Diseases
  • Related Signaling Pathways
Please refer to Sirukumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Sirukumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "Sirukumab"

Anti-Human IL6 Recombinant Antibody (Sirukumab)
Recombinant monoclonal antibody to IL6. Sirukumab (CNTO 136) is a human monoclonal antibody designed for the treatment of rheumatoid arthritis.
DrugMonitor™ Anti-Sirukumab Antibody (VS-1224-YC1096)
Sirukumab is a fully human IgG1 kappa monoclonal antibody selectively blocking circulating IL-6, used in trials for giant cell arteritis and rheumatoid arthritis. The DrugMonitor™ Anti-Sirukumab Antibody (VS-1224-YC1096) is an anti-drug antibody (ADA) against Sirukumab. This drug-based antibody is raised in mice immunized with the Sirukumab. The anti-Sirukumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Sirukumab in samples.

See other products for "IL6"

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CAT Product Name Application Type
TAB-253 Anti-Human IL-6 Recombinant Antibody (Olokizumab) WB, ELISA, FC, IP, FuncS, IF, Neut IgG4 - kappa
TAB-0172CL Human Anti-IL6 Recombinant Antibody (TAB-0172CL) ELISA, Block, In vivo Human IgG
TAB-0173CL Human Anti-IL6 Recombinant Antibody (TAB-0173CL) ELISA, Block, In vivo Human IgG1
TAB-678LC Anti-human IL6 Recombinant Antibody (BA399) (TAB-678LC) ELISA, FC, Inhib Humanized antibody
TAB-678LC-S(P) Anti-human IL6 scFv Fragment (BA399) ELISA, FC Humanized antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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