Afuco™ Anti-IL6R ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-032ML) (CAT#: AFC-TAB-032ML)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to IL6R. It is a human monoclonal antibody that can be potentially used in the treatment of Neuromyelitis optica (NMO).
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
WB
Figure 1 Human Anti-Human IL6R Antibody (AFC-TAB-032ML) in WB
Western blot analysis of AFC-TAB-032ML was performed by loading Human IL6R Protein (His Tag) in reduced condition Lane 1, Lane 2, Lane 3 (0.1 μg, 0.3 μg, 0.6 μg) onto a 12% Tris-HCl polyacrylamide gel. Proteins were transferred to a CN membrane and blocked with 5% skim milk for at least one hour. Membranes were probed with TAB-453CT (2 μg/mL) and HRP-conjugated goat anti-human IgG as a secondary antibody (1: 2000). Chemiluminescent detection was performed.
DB
Figure 2 Human Anti-Human IL6R Antibody (AFC-TAB-032ML) in DB
Dot Blot analysis of AFC-TAB-032ML was performed by coating with Human IL6R Protein (His Tag).
AFC-TAB-032ML incubation concentration: 2 μg/mL.
HRP-conjugated goat anti-human IgG as a secondary antibody (1: 2000)
ELISA
Figure 3 Human Anti-Human IL6R Antibody (AFC-TAB-032ML) in ELISA
ELISA analysis of AFC-TAB-032ML was performed by coating with Human IL6R Protein (His Tag). Then blocked with BSA and incubated with AFC-TAB-032ML. The HRP-conjugated goat anti-human IgG as a secondary antibody (1: 2000). Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Specificity
- Human IL6R
- Species Reactivity
- Human
- Applications
- ELISA, IHC, FC, IP, IF, FuncS
- Conjugate
- Unconjugated
- Generic Name
- Satralizumab
- Related Disease
- Neuromyelitis optica (NMO)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Related Resources
Please refer to Satralizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Satralizumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Satralizumab"
DrugMonitor™ Anti-Satralizumab Antibody (VS-1224-YC1063)Satralizumab is a subcutaneously injected anti-IL-6 receptor monoclonal antibody for the treatment of neuromyelitis optica spectrum disorder (NMOSD). The DrugMonitor™ Anti-Satralizumab Antibody (VS-1224-YC1063) is an anti-drug antibody (ADA) against Satralizumab. This drug-based antibody is raised in mice immunized with the Satralizumab. The anti-Satralizumab antibody may be used in ELISA, pharmacokinetics (PK), and pharmacodynamics (PD) analyses, or serves as a reference standard in ADA assays. It also is an excellent tool for therapeutic drug monitoring, allowing to evaluate the drug efficacy and determine the drug concentration of the Satralizumab in samples.
See other products for "IL6R"
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-026 | Anti-Human IL6R Recombinant Antibody (TAB-026) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1, kappa |
| TAB-691LC | Human Anti-IL6R Recombinant Antibody (TAB-691LC) | ELISA | Humanized IgG2, κ |
| TAB-692LC | Anti-human IL6R Recombinant Antibody (TAB-692LC) | ELISA | Humanized antibody |
| TAB-696LC | Human Anti-IL6R Recombinant Antibody (TAB-696LC) | Block, ELISA, FC, Inhib | Humanized antibody |
| TAB-697LC | Human Anti-IL6R Recombinant Antibody (TAB-697LC) | ELISA | Humanized antibody |
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