Afuco™ Anti-IL6R ADCC Recombinant Antibody (Satralizumab), ADCC Enhanced (CAT#: AFC-TAB-032ML)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to IL6R. Satralizumab is a human monoclonal antibody that can be potentially used in the treatment of Neuromyelitis optica (NMO).
Specific Inquiry
WB
Figure 1 Human Anti-Human IL6R Antibody (AFC-TAB-032ML) in WB
Western blot analysis of AFC-TAB-032ML was performed by loading Human IL6R Protein (His Tag) in reduced condition Lane 1, Lane 2, Lane 3 (0.1 μg, 0.3 μg, 0.6 μg) onto a 12% Tris-HCl polyacrylamide gel. Proteins were transferred to a CN membrane and blocked with 5% skim milk for at least one hour. Membranes were probed with TAB-453CT (2 μg/mL) and HRP-conjugated goat anti-human IgG as a secondary antibody (1: 2000). Chemiluminescent detection was performed.
DB
Figure 2 Human Anti-Human IL6R Antibody (AFC-TAB-032ML) in DB
Dot Blot analysis of AFC-TAB-032ML was performed by coating with Human IL6R Protein (His Tag).
AFC-TAB-032ML incubation concentration: 2 μg/mL.
HRP-conjugated goat anti-human IgG as a secondary antibody (1: 2000)
ELISA
Figure 3 Human Anti-Human IL6R Antibody (AFC-TAB-032ML) in ELISA
ELISA analysis of AFC-TAB-032ML was performed by coating with Human IL6R Protein (His Tag). Then blocked with BSA and incubated with AFC-TAB-032ML. The HRP-conjugated goat anti-human IgG as a secondary antibody (1: 2000). Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.
Specifications
- Immunogen
- The details of the immunogen for this antibody are not available.
- Host Species
- Human
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Specificity
- Human IL6R
- Species Reactivity
- Human
- Clone
- Satralizumab
- Applications
- ELISA, IHC, FC, IP, IF, FuncS
- Conjugate
- Unconjugated
- Generic Name
- Satralizumab
- Related Disease
- Neuromyelitis optica (NMO)
Product Property
- Purity
- >95% by SDS-PAGE
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Related Resources
Please refer to Satralizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Satralizumab.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "Satralizumab"
Anti-Human IL6R Recombinant Antibody (Satralizumab)Recombinant monoclonal antibody to IL6R. Satralizumab is a human monoclonal antibody that can be potentially used in the treatment of Neuromyelitis optica (NMO).
See other products for "IL6R"
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1237z | Mouse Anti-IL6R Recombinant Antibody (clone 23B11) | ICC, IF, IHC, FC, IP, ELISA | Mouse IgG1 |
| HPAB-0016-YC | Human Anti-IL6R Recombinant Antibody (HPAB-0016-YC) | ELISA, Neut | Human IgG |
| HPAB-0251CQ | Human Anti-IL6R Recombinant Antibody (HPAB-0251CQ) | ELISA, FC, Block | Human IgG4 |
| HPAB-0034-WJ | Mouse Anti-IL6R Recombinant Antibody (clone 8C1D8B5) | ELISA, WB | Mouse IgG1 |
| HPAB-0165-YJ | Human Anti-IL6R Recombinant Antibody (HPAB-0165-YJ) | ELISA, Block, Inhib | Humanized IgG1, κ |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-026 | Anti-Human IL6R Recombinant Antibody (Tocilizumab/Atlizumab) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1 - kappa |
| TAB-691LC-F(E) | Human Anti-IL6R Recombinant Antibody; Fab Fragment (TAB-691LC-F(E)) | ELISA | Humanized Fab |
| TAB-692LC-F(E) | Anti-human IL6R Fab Fragment (BOW070) | ELISA | Humanized antibody |
| TAB-696LC-F(E) | Human Anti-IL6R Recombinant Antibody; Fab Fragment (TAB-696LC-F(E)) | ELISA | Humanized Fab |
| TAB-697LC-F(E) | Human Anti-IL6R Recombinant Antibody; Fab Fragment (TAB-697LC-F(E)) | ELISA | Humanized Fab |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-L080E | IL6-PE immunotoxin | Cytotoxicity assay, Functional assay | |
| AGTO-L080D | IL6-DT immunotoxin | Cytotoxicity assay, Functional assay |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBL-245 | Human Anti-IL6R Recombinant Antibody (clone 6RL9); scFv Fragment | WB, Neut, FuncS | Human scFv |
| HPAB-0016-YC-S(P) | Human Anti-IL6R Recombinant Antibody; scFv Fragment (HPAB-0016-YC-S(P)) | ELISA, Neut | Human scFv |
| HPAB-AP718-YC-S(P) | Human Anti-IL6R Recombinant Antibody (clone A7); scFv Fragment | ELISA, Inhib, FuncS | Human scFv |
| HPAB-AP719-YC-S(P) | Human Anti-IL6R Recombinant Antibody (clone B10); scFv Fragment | ELISA | Human scFv |
| HPAB-AP720-YC-S(P) | Human Anti-IL6R Recombinant Antibody (clone D2); scFv Fragment | ELISA | Human scFv |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-690LC | Anti-human IL6R Recombinant Antibody (PM-1) (TAB-690LC) | ELISA | |
| TAB-694LC | Rabbit Anti-IL6R Recombinant Antibody (TAB-694LC) | ELISA | Rabbit IgG |
| TAB-690LC-F(E) | Anti-human IL6R Fab Fragment (PM-1) | ELISA | |
| TAB-694LC-F(E) | Rabbit Anti-IL6R Recombinant Antibody; Fab Fragment (TAB-694LC-F(E)) | ELISA | Rabbit Fab |
| TAB-695LC-F(E) | Rabbit Anti-IL6R Recombinant Antibody; Fab Fragment (TAB-695LC-F(E)) | ELISA | Rabbit Fab |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1485CQ | Mouse Anti-IL6R Recombinant Antibody (clone CBL212) | FC, ELISA, Neut | Mouse IgG1, κ |
| NEUT-1486CQ | Mouse Anti-IL6R Recombinant Antibody (clone CBL261) | FC, Neut | Mouse IgG1 |
| NEUT-1487CQ | Mouse Anti-IL6R Recombinant Antibody (clone CBL279) | Neut, WB, ELISA, FC | Mouse IgG1 |
| NEUT-1489CQ | Mouse Anti-IL6R Recombinant Antibody (clone CBL425) | WB, FC, CyTOF, ELISA, Neut | Mouse IgG1 |
| NEUT-1491CQ | Mouse Anti-IL6R Recombinant Antibody (clone MM0409-6M30) | WB, Neut | Mouse IgG1 |
Blocking Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1488CQ | Mouse Anti-IL6R Recombinant Antibody (clone B-F19) | Block | Mouse IgG1 |
| NEUT-1490CQ | Mouse Anti-IL6R Recombinant Antibody (clone B-R6) | IHC-Fr, Inhib, FC, IP | Mouse IgG1 |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0331-CN-F(E) | Human Anti-IL6R Recombinant Antibody (HPAB-0331-CN-F(E)); Fab Fragment | ELISA, FC, Neut | Human Fab |
| HPAB-0332-CN-F(E) | Human Anti-IL6R Recombinant Antibody (HPAB-0332-CN-F(E)); Fab Fragment | ELISA, FC, Block | Human Fab |
| HPAB-0333-CN-F(E) | Human Anti-IL6R Recombinant Antibody (HPAB-0333-CN-F(E)); Fab Fragment | ELISA, FC, Block | Human Fab |
| HPAB-0718-CN-F(E) | Human Anti-IL6R Recombinant Antibody; Fab Fragment (HPAB-0718-CN-F(E)) | ELISA, Neut | Humanized Fab |
| HPAB-0719-CN-F(E) | Human Anti-IL6R Recombinant Antibody; Fab Fragment (HPAB-0719-CN-F(E)) | ELISA, Neut | Humanized Fab |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-026 | Afuco™ Anti-IL6R ADCC Recombinant Antibody (Tocilizumab/Atlizumab), ADCC Enhanced | ELISA, FC, IP, FuncS, IF, Neut | ADCC enhanced antibody |
| AFC-TAB-691LC | Afuco™ Anti-IL6R ADCC Recombinant Antibody (Sapelizumab), ADCC Enhanced | ELISA | ADCC enhanced antibody |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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