Afuco™ Anti-IL6R ADCC Recombinant Antibody (Tocilizumab/Atlizumab), ADCC Enhanced (CAT#: AFC-TAB-026)

This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human IL6R. Tocilizumab (INN, or atlizumab is an immunosuppressive drug, mainly for the treatment of rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of RA in children. It is a humanized monoclonal antibody against the interleukin-6 receptor (IL-6R). Interleukin 6 (IL-6) is a cytokine that plays an important role in immune response and is implicated in the pathogenesis of many diseases, such as autoimmune diseases, multiple myeloma and prostate cancer.


Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Fc Engineering:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
RNA Expression

Specifications

  • Immunogen
  • IL-6R bound to Sepharose4B.
  • Host Species
  • Human
  • Derivation
  • Humanized (from mouse)
  • Type
  • ADCC enhanced antibody
  • Species Reactivity
  • Human
  • Clone
  • Tocilizumab/Atlizumab
  • Applications
  • ELISA, FC, IP, FuncS, IF, Neut
  • Conjugate
  • Unconjugated
  • Trade name
  • Tocilizumab, Tocilizumab
  • Generic Name
  • Tocilizumab/Atlizumab

Product Property

  • Purity
  • >95% by SDS-PAGE
  • Storage
  • Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

  • Alternative Names
  • Tocilizumab/Atlizumab; tocilizumab, rotocilizumab; 375823-41-9; atlizumab; tocilizumab; Rotocilizumab; IL6R; interleukin 6 receptor; interleukin-6 receptor subunit alpha; CD126; IL-6R 1; CD126 antigen; membrane glycoprotein 80; IL-6 receptor subunit alpha; gp80; IL6RA; IL-6RA; IL-6R-1;

Related Resources

  • Biosimilar Overview
Please refer to Tocilizumab-Atlizumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Tocilizumab-Atlizumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

See other products for "tocilizumab/Atlizumab"

Anti-Human IL6R Recombinant Antibody (Tocilizumab/Atlizumab)
Recombinant monoclonal antibody to Human IL6R. Tocilizumab (INN, or atlizumab is an immunosuppressive drug, mainly for the treatment of rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of RA in children. It is a humanized monoclonal antibody against the interleukin-6 receptor (IL-6R). Interleukin 6 (IL-6) is a cytokine that plays an important role in immune response and is implicated in the pathogenesis of many diseases, such as autoimmune diseases, multiple myeloma and prostate cancer.

See other products for "IL6R"

Immunotoxin

CAT Product Name Application Type
AGTO-L080E IL6-PE immunotoxin Cytotoxicity assay, Functional assay
AGTO-L080D IL6-DT immunotoxin Cytotoxicity assay, Functional assay

Blocking Antibody

CAT Product Name Application Type
NEUT-1488CQ Mouse Anti-IL6R Recombinant Antibody (clone B-F19) Block Mouse IgG1
NEUT-1490CQ Mouse Anti-IL6R Recombinant Antibody (clone B-R6) IHC-Fr, Inhib, FC, IP Mouse IgG1

ADCC Enhanced Antibody

CAT Product Name Application Type
AFC-TAB-032ML Afuco™ Anti-IL6R ADCC Recombinant Antibody (Satralizumab), ADCC Enhanced ELISA, IHC, FC, IP, IF, FuncS ADCC enhanced antibody
AFC-TAB-691LC Afuco™ Anti-IL6R ADCC Recombinant Antibody (Sapelizumab), ADCC Enhanced ELISA ADCC enhanced antibody

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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