Afuco™ Anti-IL6R ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-026) (CAT#: AFC-TAB-026)
This product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to Human IL6R. It is an immunosuppressive drug, mainly for the treatment of rheumatoid arthritis (RA) and systemic juvenile idiopathic arthritis, a severe form of RA in children. It is a humanized monoclonal antibody against the interleukin-6 receptor (IL-6R). Interleukin 6 (IL-6) is a cytokine that plays an important role in immune response and is implicated in the pathogenesis of many diseases, such as autoimmune diseases, multiple myeloma and prostate cancer.
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RNA Expression
Figure 1 RNA cell line category: Cell line enhanced (THP-1, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160712-IL6R
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160712-IL6R
Figure 1 RNA cell line category: Cell line enhanced (THP-1, U-266/84)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160712-IL6R
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000160712-IL6R
Specifications
- Immunogen
- IL-6R bound to Sepharose4B.
- Host Species
- Human
- Derivation
- Humanized (from mouse)
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human, Cynomolgus
- Applications
- ELISA, FC, IP, FuncS, IF, Neut, ICC
Product Property
- Purification
- Protein A purified
- Purity
- >95.0% as determined by analysis by SDS-PAGE.
- Storage
- Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- IL6R; interleukin 6 receptor; interleukin-6 receptor subunit alpha; CD126; IL-6R 1; CD126 antigen; membrane glycoprotein 80; IL-6 receptor subunit alpha; gp80; IL6RA; IL-6RA; IL-6R-1;
- Gene ID
- 3570
- UniProt ID
- P08887
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-026 | Anti-Human IL6R Recombinant Antibody (TAB-026) | ELISA, FC, IP, FuncS, IF, Neut, ICC | IgG1, kappa |
| TAB-691LC-S(P) | Human Anti-IL6R Recombinant Antibody; scFv Fragment (TAB-691LC-S(P)) | ELISA | Humanized scFv |
| TAB-692LC-S(P) | Anti-human IL6R scFv Fragment (TAB-692LC-S(P)) | ELISA | Humanized antibody |
| TAB-696LC-S(P) | Human Anti-IL6R Recombinant Antibody; scFv Fragment (TAB-696LC-S(P)) | ELISA | Humanized scFv |
| TAB-697LC-S(P) | Human Anti-IL6R Recombinant Antibody; scFv Fragment (TAB-697LC-S(P)) | ELISA | Humanized scFv |
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For Research Use Only. Not For Clinical Use.
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