Human Anti-KDR Recombinant Antibody (clone H15PCABL); Fab Fragment
CAT#: HPAB-M0130-YC-F(E)
Provided is a vascular endothelial growth factor receptor (VEGFR2) resisting monoclonal antibody. The monoclonal antibody can be specifically combined the VEGFR2 and can block combination of a VEGF (vascular endothelial growth factor) and the VEGFR2; cell biology activity analysis shows that the VEGFR2 has remarkable inhibiting effect on VEGF-induced HUVEC (human umbilical vein endothelial cells); therefore, the VEGFR2 resisting monoclonal antibody can be applied to preparation of drugs capable of blocking the VEGFR2 to serve as a new anti-tumor drug.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to nuclear membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/73577/1825_D8_31_cr5ac340707076b_selected.jpg
Normal Tissue
Figure 2 Placenta
High expression
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_2_7_val_selected.jpg
Normal Tissue
Figure 3 Colon
Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_8_3.jpg
Normal Tissue
Figure 4 Kidney
Cells in glomeruli Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_7_5.jpg
Normal Tissue
Figure 5 Testis
Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4028/11467_A_6_6.jpg
RNA Expression
Figure 6 RNA cell line category: Group enriched (HUVEC TERT2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000128052-KDR
❮
❯
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized Fab
- Specificity
- Human KDR
- Species Reactivity
- Human
- Clone
- H15PCABL
- Applications
- ELISA, Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Kinase Insert Domain Receptor; Kinase Insert Domain Receptor (A Type III Receptor Tyrosine Kinase); Vascular Endothelial Growth Factor Receptor 2; Protein-Tyrosine Kinase Receptor Flk-1; Fetal Liver Kinase 1; EC 2.7.10.1; VEGFR2; FLK1; Tyrosine Kinase Growth Factor Receptor;
- Gene ID
- 3791
- UniProt ID
- P35968
REVIEWS AND Q&AS
CITATIONS
RESOURCES
DOWNLOADS
RELATED PRODUCTS
Inquiry
Navs
Customer Review
There are currently no Customer reviews or questions for HPAB-M0130-YC-F(E). Click the button above to contact us or submit your feedback about this product.
Submit Your Publication
Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone H15PCABL"
- CAT
- Product Name
See other products for "KDR"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B066(A) | Recombinant Anti-human KDR Intrabody [(D-Arg)9] | FC, IF, FuncS | scFv-(D-Arg)9 |
| IAB-B066(G) | Recombinant Anti-human KDR Intrabody [+36 GFP] | CO-IP, FuncS | scFv-(+36GFP) |
| IAB-B066(T) | Recombinant Anti-human KDR Intrabody [Tat] | IF, ELISA, FuncS | scFv-Tat |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-202 | Humanized Anti-KDR Recombinant Antibody (clone Alacizumab); di - Fab' Fragment | IF, IP, Neut, FuncS, ELISA, FC, ICC | Humanized (from mouse) di - Fab' |
| TAB-411CQ | Anti-Human KDR Recombinant Antibody (HLX06) | ELISA | Humanized antibody |
| TAB-411CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (HLX06) | ELISA | Humanized antibody |
| TAB-411CQ-F(E) | Anti-Human KDR Recombinant Antibody Fab Fragment (HLX06) | ELISA | Humanized antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G047E | Anti-KDR immunotoxin (IgG1)-PE | Cytotoxicity assay, Function study |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0298CL | Human Anti-KDR Recombinant Antibody (TAB-0298CL) | WB, FC, ELISA, Inhib, Neut, FuncS | Human IgG |
| TAB-0299CL | Human Anti-KDR Recombinant Antibody (TAB-0299CL) | WB, FC, Inhib, Neut | Human IgG |
| TAB-0298CL-F(E) | Human Anti-KDR Recombinant Antibody; Fab Fragment (TAB-0298CL-F(E)) | FC, ELISA, Inhib, Neut, FuncS | Human Fab |
| TAB-0299CL-F(E) | Human Anti-KDR Recombinant Antibody; Fab Fragment (TAB-0299CL-F(E)) | WB, FC, Inhib, Neut | Human Fab |
| TAB-322CQ | Anti-Human KDR Recombinant Antibody (AK404R) | ELISA, WB, Inhib | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PSBC-204 | Mouse Anti-KDR Recombinant Antibody (clone mAb6.64); scFv Fragment | Neut, Block | Mouse scFv |
| HPAB-0246-WJ-S(P) | Human Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-0246-WJ-S(P)) | ELISA, IF, FC | Human scFv |
| HPAB-M0126-YC-S(P) | Human Anti-KDR Recombinant Antibody (clone RD); scFv Fragment | ELISA | Human scFv |
| HPAB-M0127-YC-S(P) | Human Anti-KDR Recombinant Antibody (clone PCABHL3); scFv Fragment | ELISA, Inhib | Humanized scFv |
| HPAB-M0128-YC-S(P) | Human Anti-KDR Recombinant Antibody (clone PCABHL5); scFv Fragment | ELISA, Inhib | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-326CQ | Rat Anti-Kdr Recombinant Antibody (TAB-326CQ) | ELISA, IHC | Rat IgG |
| TAB-331CQ | Anti-Human KDR Recombinant Antibody (6.64) | IHC, ELISA | Mouse IgG1 |
| TAB-332CQ | Anti-Human KDR Recombinant Antibody (4.13) | ELISA, FC, IHC | |
| TAB-326CQ-F(E) | Rat Anti-Kdr Recombinant Antibody; Fab Fragment (TAB-326CQ-F(E)) | ELISA, FC, WB | Rat Fab |
| TAB-331CQ-F(E) | Anti-Human KDR Recombinant Antibody Fab Fragment (6.64) | ELISA, FC, IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2180MZ | Recombinant Mouse Anti-Human KDR Antibody (clone 7C22) | FuncS, WB | Mouse antibody |
| MRO-1580-CN | Recombinant Rabbit Anti-KDR Monoclonal Antibody (SU03-42) | WB, IF, IHC, IP | Rabbit IgG |
| MRO-2270-CN | Rabbit Anti-KDR Polyclonal Antibody (MRO-2270-CN) | IF, IHC, WB, FC | Rabbit IgG |
| HPAB-A1305-YJ | Mouse Anti-KDR Recombinant Antibody (clone P1C11) | WB, ELISA, FC, Block, Inhib, FuncS | Mouse IgG2a |
| HPAB-A1306-YJ | Human Anti-KDR Recombinant Antibody (clone cP1C11) | WB, ELISA, FC, Block, Inhib, FuncS | Chimeric (mouse/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0624MZ | Chicken Anti-VEGFR-2 Polyclonal IgY | IHC, WB | Chicken antibody |
| BRD-0709MZ | Chicken Anti-KDR Polyclonal IgY | WB | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1619CQ | Recombinant Mouse Anti-KDR Antibody (23B31) | WB, IP, FC, Neut | |
| NEUT-1620CQ | Recombinant Rat Anti-Kdr Antibody (CBL840) | ELISA(Cap), Neut | IgG2a |
| NEUT-1621CQ | Recombinant Rat Anti-Kdr Antibody (CBL880) | Neut, WB | IgG2 |
| NEUT-1622CQ | Recombinant Mouse Anti-KDR Antibody (6B11) | WB, Neut | IgG1 |
| NEUT-1623CQ | Recombinant Mouse Anti-KDR Antibody (CBL505) | FC, CyTOF, Neut | IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1927 | Hi-Affi™ Recombinant Rabbit Anti-KDR Monoclonal Antibody (DS1927AB) | IHC-P | IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0097-YC-F(E) | Rabbit Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-0097-YC-F(E)) | ELISA, FuncS | Rabbit Fab |
| HPAB-0098-YC-F(E) | Rabbit Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-0098-YC-F(E)) | ELISA, FuncS | Rabbit Fab |
| HPAB-0099-YC-F(E) | Rabbit Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-0099-YC-F(E)) | ELISA, FuncS | Rabbit Fab |
| HPAB-0246-WJ-F(E) | Human Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-0246-WJ-F(E)) | ELISA, IF, FC | Human Fab |
| HPAB-N0154-YC-F(E) | Mouse Anti-KDR Recombinant Antibody; Fab Fragment (HPAB-N0154-YC-F(E)) | ELISA, Inhib | Mouse Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-079 | Afuco™ Anti-KDR ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-079) | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0298-YJ-VHH | Recombinant Human Anti-KDR Nano Antibody (HPAB-0298-YJ-VHH) | Inhib | Human VHH |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF304 | A*24:02/Human VEGFR (SYGVLLWEI) MHC Monomer | MHC Multimer |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0125-FY19 | Human Anti-KDR (clone clone 6.64) scFv-Fc Chimera | IHC, ELISA, Inhib | Human IgG1, scFv-Fc |
| VS-0325-FY84 | Human Anti-KDR (clone 1121B) scFv-Fc Chimera | FC | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC463 | Recombinant Anti-KDR Vesicular Antibody, EV Displayed (VS-0425-YC463) | ELISA, FC, Inhib, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY3760 | Anti-KDR Immunohistochemistry Kit | IHC |
Specific Inquiry
Add to compare
See Our Custom Production in Action
Popular Products
Application: IF, IP, Neut, FuncS, ELISA, FC, WB
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
