Human Anti-KDR Recombinant Antibody (clone PCABHL3); Fab Fragment
CAT#: HPAB-M0127-YC-F(E)
Provided is a vascular endothelial growth factor receptor (VEGFR2) resisting monoclonal antibody. The monoclonal antibody can be specifically combined the VEGFR2 and can block combination of a VEGF (vascular endothelial growth factor) and the VEGFR2; cell biology activity analysis shows that the VEGFR2 has remarkable inhibiting effect on VEGF-induced HUVEC (human umbilical vein endothelial cells); therefore, the VEGFR2 resisting monoclonal antibody can be applied to preparation of drugs capable of blocking the VEGFR2 to serve as a new anti-tumor drug.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HEL
Immunofluorescent staining of human cell line HEL shows localization to nuclear membrane & vesicles.
* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/73577/1825_D8_31_cr5ac340707076b_selected.jpg
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Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized Fab
- Specificity
- Human KDR
- Species Reactivity
- Human
- Clone
- PCABHL3
- Applications
- ELISA, Inhib
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Kinase Insert Domain Receptor; Kinase Insert Domain Receptor (A Type III Receptor Tyrosine Kinase); Vascular Endothelial Growth Factor Receptor 2; Protein-Tyrosine Kinase Receptor Flk-1; Fetal Liver Kinase 1; EC 2.7.10.1; VEGFR2; FLK1; Tyrosine Kinase Growth Factor Receptor;
- Gene ID
- 3791
- UniProt ID
- P35968
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
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