Human Anti-KDR Recombinant Antibody (1V09) (CAT#: HPAB-0775-YJ)
This product is a recombinant Chimeric (rabbit/human) antibody that recognizes Human KDR.
Specific Inquiry
ELISA
Figure 1 Binding to VEGF receptors and blocking the VEGF/VEGF receptor interaction by anti-KDR/Flk-1 Fab fragments.
(A) Signal intensity of VEGF receptor-specific binders. Specific binding of selected Fabs to human VEGF receptors KDR and Flt-1 and mouse VEGF receptors Flk-1 and mFlt-1 was measured by ELISA. To allow comparison of different Fabs, the OD405 signal obtained for a given Fab on an immobilized VEGF receptor was divided by the corresponding OD405 signal on an anti-human kappa light chain antibody. (B) Inhibition of the binding of human VEGF to immobilized human and mouse VEGFR2 by various Fab fragments. Data shown represent the mean±S.D. of triplicate samples.
Popkov, M., Jendreyko, N., Gonzalez-Sapienza, G., Mage, R. G., Rader, C., & Barbas III, C. F. (2004). Human/mouse cross-reactive anti-VEGF receptor 2 recombinant antibodies selected from an immune b9 allotype rabbit antibody library. Journal of immunological methods, 288(1-2), 149-164.
FC
Figure 2 Flow cytometry analysis of rabbit/human Fab binding to human (HUVEC and HMEC-1) and mouse (MS1) endothelial cell lines.
Flow cytometry histograms show the binding of rabbit/human Fabs as a bold line. The background of FITC-conjugated secondary antibodies is shown as a thin line. Human Fab was used as negative control (dashed line).
Popkov, M., Jendreyko, N., Gonzalez-Sapienza, G., Mage, R. G., Rader, C., & Barbas III, C. F. (2004). Human/mouse cross-reactive anti-VEGF receptor 2 recombinant antibodies selected from an immune b9 allotype rabbit antibody library. Journal of immunological methods, 288(1-2), 149-164.
Specifications
- Immunogen
- A complex of equimolar amounts of KDR and VEGF
- Host Species
- Human
- Derivation
- Chimeric (rabbit/human)
- Type
- Chimeric (rabbit/human) IgG1
- Specificity
- Human
- Species Reactivity
- Human
- Clone
- 1V09
- Applications
- ELISA, FC
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in ELISA, Flow Cytometry. It's recommended that the optimal antibody concentration, dilution, incubition time, etc. be carefully titrated in specific assays.
Target
- Alternative Names
- FLK1; CD309; VEGFR; VEGFR2; vascular endothelial growth factor receptor 2; fetal liver kinase-1; kinase insert domain receptor (a type III receptor tyrosine kinase); protein-tyrosine kinase receptor Flk-1; soluble VEGFR2; tyrosine kinase growth factor receptor
- Gene ID
- 3791
- UniProt ID
- P35968
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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See other products for "Clone 1V09"
See other products for "KDR"
Intrabody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| IAB-B066(A) | Recombinant Anti-human KDR Intrabody [(D-Arg)9] | FC, IF, FuncS | scFv-(D-Arg)9 |
| IAB-B066(G) | Recombinant Anti-human KDR Intrabody [+36 GFP] | CO-IP, FuncS | scFv-(+36GFP) |
| IAB-B066(T) | Recombinant Anti-human KDR Intrabody [Tat] | IF, ELISA, FuncS | scFv-Tat |
Humanized Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-202 | Humanized Anti-KDR Recombinant Antibody (clone Alacizumab); di - Fab' Fragment | IF, IP, Neut, FuncS, ELISA, FC, ICC | Humanized (from mouse) di - Fab' |
| TAB-411CQ | Anti-Human KDR Recombinant Antibody (HLX06) | ELISA | Humanized antibody |
| TAB-411CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (HLX06) | ELISA | Humanized antibody |
| TAB-411CQ-F(E) | Anti-Human KDR Recombinant Antibody Fab Fragment (HLX06) | ELISA | Humanized antibody |
Immunotoxin
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AGTO-G047E | Anti-KDR immunotoxin (IgG1)-PE | Cytotoxicity assay, Function study |
Recombinant Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABC-204 | Human Anti-KDR Recombinant Antibody (clone mAb6.64) | ELISA, Block | Chimeric (mouse/human) IgG |
| HPAB-M0126-YC | Human Anti-KDR Recombinant Antibody (clone RD) | ELISA | Human IgG |
| HPAB-M0127-YC | Human Anti-KDR Recombinant Antibody (clone PCABHL3) | ELISA, Inhib | Humanized IgG |
| HPAB-M0128-YC | Human Anti-KDR Recombinant Antibody (clone PCABHL5) | ELISA, Inhib | Humanized IgG |
| HPAB-M0129-YC | Human Anti-KDR Recombinant Antibody (clone PCABHL7) | ELISA, Inhib | Humanized IgG |
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBC-204 | Human Anti-KDR Recombinant Antibody (clone mAb6.64); Fab Fragment | Neut, Block | Chimeric (mouse/human) Fab |
| HPAB-0251-FY-F(E) | Human Anti-KDR Recombinant Antibody (clone 043HAb-1); Fab Fragment | ELISA | Human Fab |
| HPAB-0252-FY-F(E) | Human Anti-KDR Recombinant Antibody (clone 043HAb-2); Fab Fragment | ELISA | Human Fab |
| HPAB-0253-FY-F(E) | Human Anti-KDR Recombinant Antibody (clone 043HAb-3); Fab Fragment | ELISA | Human Fab |
| HPAB-0254-FY-F(E) | Human Anti-KDR Recombinant Antibody (clone 043HAb-4); Fab Fragment | ELISA | Human Fab |
Mouse Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-326CQ | Rat Anti-Kdr Recombinant Antibody (TAB-326CQ) | ELISA, IHC | Rat IgG |
| TAB-331CQ | Anti-Human KDR Recombinant Antibody (6.64) | IHC, ELISA | Mouse IgG1 |
| TAB-326CQ-S(P) | Rat Anti-Kdr Recombinant Antibody; scFv Fragment (TAB-326CQ-S(P)) | ELISA, FC, WB | Rat scFv |
| TAB-331CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (6.64) | ELISA, FC, IHC | |
| TAB-332CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (4.13) | ELISA, FC, IHC |
Human Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-322CQ-F(E) | Anti-Human KDR Recombinant Antibody Fab Fragment (AK404R) | ELISA, WB | Human antibody |
| TAB-325CQ-F(E) | Human Anti-KDR Recombinant Antibody; Fab Fragment (TAB-325CQ-F(E)) | ELISA, FC | Human Fab |
| TAB-329CQ-F(E) | Human Anti-KDR Recombinant Antibody; Fab Fragment (TAB-329CQ-F(E)) | ELISA, WB, Neut | Human Fab |
| TAB-330CQ-F(E) | Mouse Anti-KDR Recombinant Antibody; Fab Fragment (TAB-330CQ-F(E)) | ELISA, WB, Neut | Mouse Fab |
| TAB-333CQ-F(E) | Human Anti-KDR Recombinant Antibody; Fab Fragment (TAB-333CQ-F(E)) | ELISA, FC | Human Fab |
Chicken IgY Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0624MZ | Chicken Anti-VEGFR-2 Polyclonal IgY | IHC, WB | Chicken antibody |
| BRD-0709MZ | Chicken Anti-KDR Polyclonal IgY | WB | Chicken antibody |
Neutralizing Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-1619CQ | Recombinant Mouse Anti-KDR Antibody (23B31) | WB, IP, FC, Neut | |
| NEUT-1620CQ | Recombinant Rat Anti-Kdr Antibody (CBL840) | ELISA(Cap), Neut | IgG2a |
| NEUT-1621CQ | Recombinant Rat Anti-Kdr Antibody (CBL880) | Neut, WB | IgG2 |
| NEUT-1622CQ | Recombinant Mouse Anti-KDR Antibody (6B11) | WB, Neut | IgG1 |
| NEUT-1623CQ | Recombinant Mouse Anti-KDR Antibody (CBL505) | FC, CyTOF, Neut | IgG1 |
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-1927 | Hi-Affi™ Recombinant Rabbit Anti-KDR Monoclonal Antibody (DS1927AB) | IHC-P | IgG |
ADCC Enhanced Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-079 | Afuco™ Anti-KDR ADCC Recombinant Antibody (Ramucirumab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
scFv Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-N0154-YC-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-N0154-YC-S(P)) | ELISA, Inhib | Mouse scFv |
| HPAB-0476-FY-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-0476-FY-S(P)) | Inhib | Mouse scFv |
| HPAB-0775-YJ-S(P) | Rabbit Anti-KDR Recombinant Antibody (1V09); scFv Fragment | ELISA, FC | Rabbit scFv |
| HPAB-0776-YJ-S(P) | Rabbit Anti-KDR Recombinant Antibody (2V05); scFv Fragment | ELISA, FC | Rabbit scFv |
| HPAB-0777-YJ-S(P) | Rabbit Anti-Mouse KDR Recombinant Antibody (VC16); scFv Fragment | ELISA, FC | Rabbit scFv |
Single-domain Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0298-YJ-VHH | Recombinant Human Anti-KDR Nano Antibody (NTV1) | Inhib | Human VHH |
MHC Tetramer for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF304 | A*24:02/Human VEGFR (SYGVLLWEI) MHC Monomer | MHC Multimer | |
| MHC-YF772 | H-2Db/Human VEGFR2/KDR fragment 1 (FSNSTNDILI) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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