Human Anti-KIT Recombinant Antibody; Fab Fragment (HPAB-N0157-YC-F(E)) (CAT#: HPAB-N0157-YC-F(E))
This product is a recombinant humanized antibody Fab fragment that recognizes human and cynomolgus monkey cKIT EDC. This antibody dose not cross-react with rat cKIT.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEK 293
(Immunofluorescent staining of human cell line HEK 293 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73252/1469_D7_6_selected.jpg
(Immunofluorescent staining of human cell line HEK 293 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73252/1469_D7_6_selected.jpg
Figure 2 High expression in breast
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4471/ihc_selected.jpg
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4471/ihc_selected.jpg
Figure 3 High expression in lung.
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3288/8181_A_1_4_val_selected.jpg
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3288/8181_A_1_4_val_selected.jpg
Figure 4 Skin
(Melanocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3288/8181_B_8_1.jpg
(Melanocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3288/8181_B_8_1.jpg
Figure 5 RNA cell line category: Group enriched (HEL, HMC-1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157404-KIT
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157404-KIT
Specifications
- Immunogen
- The ECD of human cKIT
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized Fab
- Specificity
- Human KIT
- Species Reactivity
- Human, Cynomolgus monkey
- Applications
- ELISA, Inhib, FuncS
- Related Disease
- Cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- KIT Proto-Oncogene Receptor Tyrosine Kinase; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog; Tyrosine-Protein Kinase Kit; Piebald Trait Protein; Proto-Oncogene C-Kit; EC 2.7.10.1; P145 C-Kit; SCFR; PBT; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene-Like Protein
- Gene ID
- 3815
- UniProt ID
- P10721
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "KIT"
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Please select product type
Recombinant Antibody
Humanized Antibody
ADCC Enhanced Antibody
scFv Fragment Antibody
Fab Fragment Antibody
Human Antibody
Mouse Antibody
Chicken IgY Antibody
Blocking Antibody
Neutralizing Antibody
Rabbit Monoclonal Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1436z | Mouse Anti-KIT Recombinant Antibody (clone 21G5) | ELISA, IHC, WB | Mouse IgG |
| TAB-468LC | Human Anti-KIT Recombinant Antibody (TAB-468LC) | ELISA | Human IgG1, κ |
| MRO-0366-CN | Recombinant Rabbit Anti-KIT Monoclonal Antibody (CBACN-149) | WB, IHC | Rabbit IgG |
| HPAB-N0156-YC | Mouse Anti-KIT Recombinant Antibody (HPAB-N0156-YC) | ELISA, Inhib, FuncS | Mouse IgG |
| HPAB-N0157-YC | Human Anti-KIT Recombinant Antibody (HPAB-N0157-YC) | ELISA, Inhib, FuncS | Humanized IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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