Human Anti-KIT Recombinant Antibody (HPAB-1950-FY)

Name: Human Anti-KIT Recombinant Antibody (HPAB-1950-FY)
SKU: HPAB-1950-FY
Rating: 5 (1 reviews)

CAT#: HPAB-1950-FY

This product is a recombinant human antibody that recognizes the D4 domain of human KIT. As determined by solid phase ELISA, the EC₅₀ for the binding affinity of this antibody to the D4/D5 region of human KIT was calculated to be approximately 23 pM.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line HEK 293

Immunofluorescent staining of human cell line HEK 293 shows localization to plasma membrane.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/73252/1469_D7_6_selected.jpg

Normal Tissue Figure 2 High expression in breast

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/4471/ihc_selected.jpg

Normal Tissue Figure 3 High expression in lung.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3288/8181_A_1_4_val_selected.jpg

Normal Tissue Figure 4 Skin

Melanocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/3288/8181_B_8_1.jpg

RNA Expression Figure 5 RNA cell line category: Group enriched (HEL, HMC-1)

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157404-KIT

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Specifications

Host Species
Human

Derivation
Humanized

Type
Humanized IgG

Specificity
Human KIT

Species Reactivity
Human, Canine, Monkey

Applications
ELISA, FC, Inhib

Product Property

Purity
>95% as determined by SDS-PAGE

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
KIT Proto-Oncogene Receptor Tyrosine Kinase; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene Homolog; Tyrosine-Protein Kinase Kit; Piebald Trait Protein; Proto-Oncogene C-Kit; EC 2.7.10.1; P145 C-Kit; SCFR; PBT; V-Kit Hardy-Zuckerman 4 Feline Sarcoma Viral Oncogene-Like Protein

Gene ID
3815

UniProt ID
P10721

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - HPAB-1950-FY.pdf

MSDS

MSDS - HPAB-1950-FY.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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