AbPlus™ Anti-PDCD1 Magnetic Beads (VS-0724-YC1287)

Name: AbPlus™ Anti-PDCD1 Magnetic Beads (VS-0724-YC1287)
SKU: VS-0724-YC1287
Rating: 5 (1 reviews)

CAT#: VS-0724-YC1287

The AbPlus Anti-PDCD1 Magnetic Beads (VS-0724-YC1287) is an innovative affinity resin which is bound with anti-PDCD1 specific antibody. The beads were designed for small-scale affinity purification and immunoprecipitation (IP) of PDCD1 protein under native and denaturing conditions.

Gene Expression

Normal Tissue Figure 1 Lymph node

Germinal center cells
Staining:

Medium

Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_9_8.jpg

Normal Tissue Figure 2 Tonsil

Germinal center cells
Staining:

High

Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:

Medium

Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_6_8.jpg

RNA Expression Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, RPMI-8226)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1

❮

❯

Specifications

Applications
Immunoprecipitation, Protein Purification

Matrix
Magnetic bead

Bead Ligand
Anti-PDCD1 specific antibody

Target
PDCD1

Immunogen
Synthetic peptide corresponding to the center region of the Cynomolgus PD-1/PDCD1.

Target Species
Cynomolgus

Bead Capacity
40 mg/mL

Bead size
25 μm

Format
Suspension

Concentration
2 mg/mL

Buffer
PBS, pH 7.4

Preservative
0.1% Sodium azide

Storage
Stored at 4°C, and is stable for up to 2 years. Do not centrifuge, dry or freeze the magnetic beads.

Applications

Application Notes
The beads are in suspension and will settle upon storage. Prior to use, mix the vial gently (do not vortex) to ensure delivery of proper bead volume.

Target

Introduction
This gene encodes a cell surface membrane protein of the immunoglobulin superfamily. This protein is expressed in pro-B-cells and is thought to play a role in their differentiation. In mice, expression of this gene is induced in the thymus when anti-CD3 antibodies are injected and large numbers of thymocytes undergo apoptosis. Mice deficient for this gene bred on a BALB/c background developed dilated cardiomyopathy and died from congestive heart failure. These studies suggest that this gene product may also be important in T cell function and contribute to the prevention of autoimmune diseases. [provided by RefSeq, Jul 2008]

Alternative Names
Programmed Cell Death 1; Systemic Lupus Erythematosus Susceptibility 2; Protein PD-1; HPD-1; PD1; Programmed Cell Death 1 Protein; Programmed Cell Death Protein 1;

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Datasheet

Datasheet - VS-0724-YC1287.pdf

MSDS

MSDS - VS-0724-YC1287.pdf

COA

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