Human Anti-PDCD1 Agonistic Antibody (clone 949)

Name: Human Anti-PDCD1 Agonistic Antibody (clone 949)
SKU: VS-0724-XY59
Rating: 5 (1 reviews)

CAT#: VS-0724-XY59

It is an agonistic human antibody targeting the PDCD1 (Programmed cell death protein 1), which is an immune-inhibitory receptor expressed in activated T cells. This antibody specifically recognizes and binds to human PDCD1. It has been determined using ELISA, Bio-layer interferometry, Flow cytometry, Agonistic assays and Inhibition assay.

Gene Expression

Normal Tissue Figure 1 Lymph node

Germinal center cells
Staining:

Medium

Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_9_8.jpg

Normal Tissue Figure 2 Tonsil

Germinal center cells
Staining:

High

Intensity: Strong
Quantity: 75%-25%
Location: Cytoplasmic/
membranous
Non-germinal center cells
Staining:

Medium

Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/35981/161493_A_6_8.jpg

RNA Expression Figure 3 RNA cell line category: Cell line enhanced (JURKAT, MOLT-4, RPMI-8226)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000188389-PDCD1

❮

❯

Specifications

Immunogen
Recombinant protein PDCD1

Host Species
Human

Derivation
Hybridomas

Type
Human IgG

Specificity
PDCD1

Species Reactivity
Human

Clone
949

Applications
ELISA, BLI, FC, Agonistic assays

Product Property

Purification
Protein A purified

Purity
>95%, determined by SDS-PAGE

Format
Liquid

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1

Gene ID
5133

UniProt ID
Q15116

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS-0724-XY59.pdf

MSDS

MSDS - VS-0724-XY59.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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