Mouse Anti-STAT3 Monoclonal Antibody (VS7-0425-WR927) (CAT#: VS7-0425-WR927)
This product is a mouse IgG antibody that binds to human STAT3. The antibody can be used for WB, IHC-P, IF, ICC, and ELISA assays. It cross reacts with mouse and monkey.
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1671/if_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1671/if_selected.jpg
Figure 2 IHC staining of human placenta
(Immunohistochemical staining of human placenta shows strong nuclear positivity and cytoplasmic in decidual cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1671/155480_A_3_7_selected.jpg
(Immunohistochemical staining of human placenta shows strong nuclear positivity and cytoplasmic in decidual cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/1671/155480_A_3_7_selected.jpg
Figure 3 IHC staining of human small intestine
(Immunohistochemical staining of human small intestine shows strong positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58603/ihc_selected.jpg
(Immunohistochemical staining of human small intestine shows strong positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/58603/ihc_selected.jpg
Figure 4 Liver
(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68241/153085_A_9_4.jpg
(Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68241/153085_A_9_4.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68242/153074_A_7_5.jpg
(Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68242/153074_A_7_5.jpg
Figure 6 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68242/153074_A_8_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68242/153074_A_8_8.jpg
Figure 7 Lung
(Alveolar cells type I Staining: Medium Intensity: Moderate Quantity: 75%-25% Alveolar cells type I Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Macrophages Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68242/153074_A_3_4.jpg
(Alveolar cells type I Staining: Medium Intensity: Moderate Quantity: 75%-25% Alveolar cells type I Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Macrophages Staining: Medium Intensity: Moderate)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68242/153074_A_3_4.jpg
Figure 8 Colon
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68242/153074_A_7_3.jpg
(Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/68242/153074_A_7_3.jpg
Figure 9 RNA cell line category: Low cell line specificity
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000168610-STAT3
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000168610-STAT3
Specifications
- Immunogen
- Recombinant human STAT3 fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human STAT3
- Species Reactivity
- Human, Mouse, Monkey
- Molecule Class
- STAT (Signal Transducers And Activators Of Transcription) Protein
- Applications
- WB, IHC-P, IF, ICC, ELISA
- Conjugate
- Unconjugated
- Related Disease
- Hyper-IgE syndrome 1, autosomal dominant, with recurrent infections (HIES1); Autoimmune disease, multisystem, infantile-onset, 1 (ADMIO1)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
- Format
- Liquid
- Concentration
- 1 mg/ml
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry: 1:200 - 1:1000
Immunofluorescence: 1:200 - 1:1000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- STAT3; ADMIO; APRF; Signal Transducer And Activator Of Transcription 3 (Acute-Phase Response Factor); Signal Transducer And Activator Of Transcription 3; HIES
- Gene ID
- 6774
- UniProt ID
- P40763
- Long Name
- Signal transducer and activator of transcription 3
- Cellular Localization
- Cytoplasm; Nucleus
- Post Translation Modifications
- Acetylation; Phosphoprotein
- Protein Refseq
- NP_001356441.1
- Function
- Activator; DNA-binding
Recommended Products
Isotype Control
Secondary Antibody
Related Resources
Endometrial Cancer
Non-small Cell Lung Cancer
Pancreatic Cancer
Throid Cancer
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MAPK Signaling Pathway
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IHC Kit and Antibody Products: Precision Tools for Immunohistochemistry
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1395z-F(E) | Recombinant Anti-Human STAT3 Antibody Fab Fragment | FC, ELISA, FuncS | Fab |
| HPAB-M0660-YC-F(E) | Human Anti-STAT3 Recombinant Antibody; Fab Fragment (HPAB-M0660-YC-F(E)) | ELISA | Human Fab |
| HPAB-M0661-YC-F(E) | Human Anti-STAT3 Recombinant Antibody; Fab Fragment (HPAB-M0661-YC-F(E)) | ELISA | Human Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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