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    Mouse Anti-STAT3 Monoclonal Antibody (VS7-0425-WR927) (CAT#: VS7-0425-WR927)

    This product is a mouse IgG antibody that binds to human STAT3. The antibody can be used for WB, IHC-P, IF, ICC, and ELISA assays. It cross reacts with mouse and monkey.

    Specific Inquiry
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    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
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    Conjugation :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm & cytosol.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1671/if_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human placenta
    Figure 2 IHC staining of human placenta
    (Immunohistochemical staining of human placenta shows strong nuclear positivity and cytoplasmic in decidual cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/1671/155480_A_3_7_selected.jpg
    Figure 3 IHC staining of human small intestine
    Figure 3 IHC staining of human small intestine
    (Immunohistochemical staining of human small intestine shows strong positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/58603/ihc_selected.jpg
    Figure 4 Liver
    Figure 4 Liver
    (Hepatocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/68241/153085_A_9_4.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in glomeruli Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Nuclear Cells in tubules Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/68242/153074_A_7_5.jpg
    Figure 6 Lymph node
    Figure 6 Lymph node
    (Germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear Non-germinal center cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/68242/153074_A_8_8.jpg
    Figure 7 Lung
    Figure 7 Lung
    (Alveolar cells type I Staining: Medium Intensity: Moderate Quantity: 75%-25% Alveolar cells type I Endothelial cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Macrophages Staining: Medium Intensity: Moderate)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/68242/153074_A_3_4.jpg
    Figure 8 Colon
    Figure 8 Colon
    (Endothelial cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous Glandular cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous nuclear)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/68242/153074_A_7_3.jpg
    RNA Expression
    Figure 9 RNA cell line category: Low cell line specificity
    Figure 9 RNA cell line category: Low cell line specificity
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000168610-STAT3

    Specifications

    • Immunogen
    • Recombinant human STAT3 fragment expressed in E. Coli.
    • Host Species
    • Mouse
    • Type
    • Mouse IgG
    • Specificity
    • Human STAT3
    • Species Reactivity
    • Human, Mouse, Monkey
    • Molecule Class
    • STAT (Signal Transducers And Activators Of Transcription) Protein
    • Applications
    • WB, IHC-P, IF, ICC, ELISA
    • Conjugate
    • Unconjugated
    • Related Disease
    • Hyper-IgE syndrome 1, autosomal dominant, with recurrent infections (HIES1); Autoimmune disease, multisystem, infantile-onset, 1 (ADMIO1)

    Product Property

    • Clonality
    • Monoclonal
    • Purity
    • >95% as determined by SDS-PAGE and SEC-HPLC analysis, Ascitic fluid
    • Format
    • Liquid
    • Concentration
    • 1 mg/ml
    • Preservative
    • 0.03% sodium azide
    • Storage
    • Centrifuge briefly prior to opening vial. Aliquot and store at -20°C for one year. Avoid repeated freeze/thaw cycles.
    • Shipping
    • Ice packs

    Applications

    • Application Notes
    • Western Blot: 1:500 - 1:2000
      Immunohistochemistry: 1:200 - 1:1000
      Immunofluorescence: 1:200 - 1:1000
      Enzyme-linked Immunosorbent Assay: 1:10000

    Target

    • Alternative Names
    • STAT3; ADMIO; APRF; Signal Transducer And Activator Of Transcription 3 (Acute-Phase Response Factor); Signal Transducer And Activator Of Transcription 3; HIES
    • Long Name
    • Signal transducer and activator of transcription 3
    • Cellular Localization
    • Cytoplasm; Nucleus
    • Post Translation Modifications
    • Acetylation; Phosphoprotein
    • Function
    • Activator; DNA-binding

    Recommended Products

    Isotype Control

    Secondary Antibody

    Related Resources

    • Related Diseases
    • Related Signaling Pathways

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "STAT3"

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    CAT Product Name Application Type
    MOB-1395z-F(E) Recombinant Anti-Human STAT3 Antibody Fab Fragment FC, ELISA, FuncS Fab
    HPAB-M0660-YC-F(E) Human Anti-STAT3 Recombinant Antibody; Fab Fragment (HPAB-M0660-YC-F(E)) ELISA Human Fab
    HPAB-M0661-YC-F(E) Human Anti-STAT3 Recombinant Antibody; Fab Fragment (HPAB-M0661-YC-F(E)) ELISA Human Fab

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