Recombinant Rabbit Anti-B2M Antibody (clone R07-8B6) (CAT#: VS3-FY129)
This product is a recombinant rabbit antibody that recognizes human, mouse and rat B2M protein. It can detect a band of approximately 14 kDa (observedd molecular weight: 14 kDa).
Specific Inquiry
WB
Figure 1. Recombinant Rabbit Anti-B2M Antibody (clone R07-8B6) in WB.
Western Blot Analysis of β2 Microglobulin in HeLa Lysates Using β2 Microglobulin.
Specifications
- Immunogen
- A synthetic peptide of human beta 2 Microglobulin
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human, Mouse and Rat B2M
- Species Reactivity
- Human, Mouse, Rat
- Clone
- R07-8B6
- Applications
- Western Blot, Immunoprecipitation
- Conjugate
- Unconjugated
- MW
- Calculated MW: 14 kDa; Observed MW: 14 kDa
Product Property
- Purification
- Affinity Purified
- Purity
- >95%
- Format
- Liquid
- Buffer
- 50 mM Tris-Glycine, pH 7.4, 0.15 M NaCl, 40% Glycerol, 0.05% BSA
- Preservative
- 0.01% Sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- Western Blot: 1/500-1/1000
Immunoprecipitation: 1/20
Target
- Alternative Names
- Beta-2-Microglobulin; Beta Chain Of MHC Class I Molecules; Beta-2-Microglobin; IMD43
- Gene ID
- 567
- UniProt ID
- P61769
- Sequence Similarities
- Belongs to the beta-2-microglobulin family.
- Cellular Localization
- Amyloid, MHC I, Secreted
- Post Translation Modifications
- Glycation of Ile-21 is observed in long-term hemodialysis patients.
- Protein Refseq
- NP_004039.1
- Function
- Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation (PubMed:25356553).
Recommended Products
Secondary Antibody
Isotype Control
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Non-Human Primate (NHP) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1431z-F(E) | Recombinant Anti-Human B2M Antibody Fab Fragment | Neut, WB, FuncS | Fab |
| HPAB-0130-FY-F(E) | Human Anti-B2M Recombinant Antibody (clone B2M-1D8); Fab Fragment | ELISA | Humanized Fab |
| HPAB-0131-FY-F(E) | Human Anti-B2M Recombinant Antibody (clone B2M-2F6); Fab Fragment | ELISA | Humanized Fab |
| HPAB-0350-FY-F(E) | Mouse Anti-B2M Recombinant Antibody (clone FY-007); Fab Fragment | ELISA | Mouse Fab |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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