Recombinant Rabbit Anti-IL1B Detection Antibody (clone R05-7O9)
CAT#: VS3-WK1687
This antibody is a rabbit recombinant antibody against human IL1B. It was developed by immunization of rabbit with recombinant human IL1B protein and then was produced as a recombinant antibody. The isotype of this product is rabbit IgG. R02-6S1 and R05-7O9 were identified as antibody pair for sandwich ELISA. As a detection antibody, the clone R05-7O9 can be used in ELISA analysis to identify human IL1B.
Specifications
- Immunogen
- Recombinant human IL1B protein
- Host Species
- Rabbit
- Type
- Rabbit IgG
- Specificity
- Human IL1B
- Species Reactivity
- Human
- Clone
- R05-7O9
- Applications
- ELISA
- Conjugate
- Unconjugated
Product Property
- Clonality
- Monoclonal
- Purification
- Protein A affinity purified
- Purity
- >95% as determined by SDS-PAGE
- Aggregation
- < 5%
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- 0.01M PBS, pH 7.2
- Storage
- Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
- Shipping
- Ice packs
Target
- Alternative Names
- Interleukin 1 Beta
- Gene ID
- 3553
- UniProt ID
- P01584
- Long Name
- Interleukin 1 Beta
- Sequence Similarities
- Belongs to the IL-1 family.
- Cellular Localization
- Cytoplasm, Lysosome, Secreted
- Post Translation Modifications
- Activation of the IL1B precursor involves a CASP1-catalyzed proteolytic cleavage. Processing and secretion are temporarily associated.
(Microbial infection) Cleavage by S.pyogenes cysteine protease SpeB promotes its activation independently of CASP1.
- Protein Refseq
- NP_000567.1
- Function
- Potent pro-inflammatory cytokin.
Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production.
Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells
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Related Diseases
Related Signaling Pathways
Downloadable Resources
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Capture antibody
- CAT
- Product Name
Isotype Control
- CAT
- Product Name
Secondary Antibody
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