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Il2

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The protein encoded by this gene is a secreted cytokine that is important for the proliferation of T and B lymphocytes. The receptor of this cytokine is a heterotrimeric protein complex whose gamma chain is also shared by interleukin 4 (IL4) and interleukin 7 (IL7). The expression of this gene in mature thymocytes is monoallelic, which represents an unusual regulatory mode for controlling the precise expression of a single gene. The targeted disruption of a similar gene in mice leads to ulcerative colitis-like disease, which suggests an essential role of this gene in the immune response to antigenic stimuli.

Targets:
CD4 & IL2
Type:
CrossMab
Application:
FuncS, Promising therapeutic agent
Targets:
CD8 & IL2
Type:
CrossMab
Application:
FuncS, Promising therapeutic agent
Aldesleukin (TP-046CL)
Protein Chemical Formula:
C690H1115N177O202S6
Protein Average Weight:
15314.8 Da
CAS Number:
85898-30-2
Target:
IL2
Species Reactivity:
Mouse
Cytokine 1:
IL2
Host:
Rat
Cytokine 1 Species:
Mouse
Molecule Class:
L Kappa; IL2-IgG2a
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
WB, IHC, FuncS
Derivation:
Mouse
Species Reactivity:
Mouse
Type:
Fab
Application:
Neut
Derivation:
Mouse
Species Reactivity:
Mouse
Type:
Fab
Application:
WB, ELISA, FuncS
Derivation:
Humanized
Type:
Humanized antibody
Application:
ELISA, FC
Derivation:
Non-immune human display library
Species Reactivity:
Mouse
Type:
Human antibody
Application:
ELISA, FC
Derivation:
Non-immune human display library
Species Reactivity:
Mouse
Type:
Human antibody
Application:
ELISA, FC
Species Reactivity:
Human
Type:
Mouse Antibody
Application:
ELISA, FC
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
WB, ELISA, Neut, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
ELISA, WB, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
Fab
Application:
IF, ELISA, FuncS
Derivation:
Mouse
Species Reactivity:
Human
Type:
scFv
Application:
ELISA, WB, FuncS
Derivation:
Humanized
Species Reactivity:
Human
Type:
Antibody
Derivation:
Mouse
Species Reactivity:
Human
Type:
IgG
Application:
WB, IHC, FuncS
Derivation:
Humanized
Type:
Humanized antibody
Application:
ELISA, FC
Derivation:
Non-immune human display library
Species Reactivity:
Mouse
Type:
Human antibody
Application:
ELISA, FC
Derivation:
Non-immune human display library
Species Reactivity:
Mouse
Type:
Human antibody
Application:
ELISA, FC
Species Reactivity:
Human
Type:
Mouse Antibody
Application:
ELISA, FC
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