Hi-Affi™ Rabbit Anti-FGFR3 Recombinant Antibody (clone DS1299AB)
CAT#: MOR-1299
Recombinant Rabbit anti-FGFR3 monoclonal antibody for WB, IHC, ICC, FC, excellent for producing superior results. Hi-Affi™ antibodies are developed from different sources, such as B cells of immunized animals, hybridoma, phage display library. The application of recombinant technology avoids the traditional ascitic fluid approach, which achieves the antibody generation in a humane way with much larger scale, greater specificity and sensitivity, and not susceptible to cell-line drift or lot-to-lot variation.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67204/1419_D10_2_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line RT4
Immunofluorescent staining of human cell line RT4 shows localization to endoplasmic reticulum.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/67204/1382_D10_2_blue_green.jpg
Normal Tissue
Figure 3 Cerebral cortex
Endothelial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Glial cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Neuronal cells
Staining: Medium
Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/membranous
Neuropil
Staining: Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4231/11838_B_7_5.jpg
Normal Tissue
Figure 4 Testis
Spermatogonia cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4231/11838_A_6_6.jpg
Normal Tissue
Figure 5 Skin
Cells in basal layer
Staining: High
Intensity: Strong
Quantity:>75%
Cells in spinous layer
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Langerhans cells
Staining: Medium
Intensity: Moderate
Quantity:>75%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/4231/11838_B_8_1.jpg
RNA Expression
Figure 6 RNA cell line category: Cell line enhanced (CACO-2, HaCaT, Hep G2, NTERA-2, RT4)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000068078-FGFR3
❮
❯
Specifications
- Host Species
- Rabbit
- Derivation
- Phage display library
- Type
- Rabbit IgG
- Specificity
- Human FGFR3
- Species Reactivity
- Human
- Clone
- DS1299AB
- Applications
- WB, IHC, ICC, FC
- Conjugate
- Unconjugated
Product Property
- Purification
- Purified with Absolute Mag™ Protein A Agarose
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Fibroblast Growth Factor Receptor 3; EC 2.7.10.1; FGFR-3; JTK4; Fibroblast Growth Factor Receptor 3 Variant 4; Achondroplasia, Thanatophoric Dwarfism; Hydroxyaryl-Protein Kinase; Tyrosine Kinase JTK4; CD333 Antigen; HSFGFR3EX; EC 2.7.10; CD333; CEK2; ACH
- Gene ID
- 2261
- UniProt ID
- P22607
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Related Diseases
Bladder Cancer
EGFR Tyrosine Kinase Inhibitor Resistance
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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|---|---|---|---|
| AGTO-G028E | Anti-FGFR3 immunotoxin (scFv)-PE | Cytotoxicity assay, Function study | |
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| AGTO-L016G | aFGF-Gel immunotoxin | Cytotoxicity assay, Functional assay |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBL-471 | Human Anti-FGFR3 Recombinant Antibody (clone R3Mab); Fab Fragment | ELISA | Human Fab |
| PSBW-162 | Human Anti-FGFR3 Recombinant Antibody (clone R3); scFv Fragment | Neut, ELISA, FC | Human scFv |
| HPAB-0157-YC-F(E) | Human Anti-FGFR3 Recombinant Antibody; Fab Fragment (HPAB-0157-YC-F(E)) | ELISA, IP, WB | Human Fab |
| HPAB-0158-YC-F(E) | Mouse Anti-FGFR3 Recombinant Antibody; Fab Fragment (HPAB-0158-YC-F(E)) | ELISA, FC | Mouse Fab |
| HPAB-0150-WJ-F(E) | Human Anti-FGFR3 Recombinant Antibody; Fab Fragment (HPAB-0150-WJ-F(E)) | ELISA | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PFBW-162 | Human Anti-FGFR3 Recombinant Antibody (clone R3); Fab Fragment | Neut, ELISA, FC | Human Fab |
| HPAB-0150-WJ-S(P) | Human Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-0150-WJ-S(P)) | ELISA | Human scFv |
| HPAB-AP654-YC-S(P) | Human Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-AP654-YC-S(P)) | ELISA, Inhib, FuncS | Human scFv |
| HPAB-AP655-YC-S(P) | Human Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-AP655-YC-S(P)) | ELISA, Inhib, FuncS | Human scFv |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| TAB-063WM | Mouse Anti-FGFR3 Recombinant Antibody (TAB-063WM) | ELISA, FC, Neut, WB | Mouse IgG |
| TAB-062WM-S(P) | Mouse Anti-FGFR3 Recombinant Antibody; scFv Fragment (TAB-062WM-S(P)) | ELISA, FC, Neut, WB | Mouse scFv |
| TAB-063WM-S(P) | Mouse Anti-FGFR3 Recombinant Antibody; scFv Fragment (TAB-063WM-S(P)) | ELISA, FC, Neut, WB | Mouse scFv |
| TAB-064WM-S(P) | Anti-Human FGFR3 Recombinant Antibody scFv Fragment (15D8) | Neut, ELISA |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-0738CT | Recombinant Mouse anti-Human FGFR3 Monoclonal antibody (NN0380-7H22) | IHC-P, WB | |
| MRO-0582-CN | Rabbit Anti-FGFR3 Recombinant Antibody (clone JM81-10) | WB, IF, IHC, FC | Rabbit IgG |
| MRO-0583-CN | Rabbit Anti-FGFR3 Recombinant Antibody (clone JM110-33) | WB, IF, IHC, FC | Rabbit IgG |
| HPAB-AP654-YC | Human Anti-FGFR3 Recombinant Antibody (HPAB-AP654-YC) | ELISA, Inhib, FuncS | Human IgG |
| HPAB-AP655-YC | Human Anti-FGFR3 Recombinant Antibody (HPAB-AP655-YC) | ELISA, Inhib, FuncS | Human IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NEUT-834CQ | Mouse Anti-FGFR3 Recombinant Antibody (clone CBL546) | Neut | Mouse IgG1 |
| NEUT-835CQ | Mouse Anti-FGFR3 Recombinant Antibody (clone CBL547) | WB, Neut | Mouse IgG1 |
| NEUT-836CQ | Mouse Anti-FGFR3 Recombinant Antibody (clone 6G11) | WB, Neut | Mouse IgG1 |
| NEUT-837CQ | Mouse Anti-FGFR3 Recombinant Antibody (clone CBL061) | WB, IHC, Neut | Mouse IgG1 |
| NEUT-838CQ | Rat Anti-Fgfr3 Recombinant Antibody (clone CBL548) | Neut | Rat IgG2a |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-XY838 | Anti-FGFR3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2544 | Anti-Mouse FGFR3 Immunohistochemistry Kit | IHC | |
| VS-0525-XY2543 | Anti-Human FGFR3 Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC387 | Recombinant Anti-FGFR3 Vesicular Antibody, EV Displayed (VS-0425-YC387) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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