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FGFR3
This gene encodes a member of the fibroblast growth factor receptor (FGFR) family, with its amino acid sequence being highly conserved between members and among divergent species. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds acidic and basic fibroblast growth hormone and plays a role in bone development and maintenance. Mutations in this gene lead to craniosynostosis and multiple types of skeletal dysplasia.
Related Diseases
Bladder Cancer
EGFR Tyrosine Kinase Inhibitor Resistance
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- Derivation: Phage display library
- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IHC, ICC, FC
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- Rat Anti-Fgfr3 Recombinant Antibody (clone CBL871) (NEUT-839CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG2
- Application: Neut
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- Rat Anti-Fgfr3 Recombinant Antibody (clone CBL548) (NEUT-838CQ)
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- Species Reactivity: Mouse
- Type: Rat IgG2a
- Application: Neut
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- Mouse Anti-FGFR3 Recombinant Antibody (clone CBL061) (NEUT-837CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, IHC, Neut
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- Mouse Anti-FGFR3 Recombinant Antibody (clone 6G11) (NEUT-836CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, Neut
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- Mouse Anti-FGFR3 Recombinant Antibody (clone CBL547) (NEUT-835CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: WB, Neut
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- Mouse Anti-FGFR3 Recombinant Antibody (clone CBL546) (NEUT-834CQ)
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- Species Reactivity: Human
- Type: Mouse IgG1
- Application: Neut
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- Rabbit Anti-FGFR3 Recombinant Antibody (clone JM110-33) (MRO-0583-CN)
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- Species Reactivity: Human, Mouse, Rat
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Rabbit Anti-FGFR3 Recombinant Antibody (clone JM81-10) (MRO-0582-CN)
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- Species Reactivity: Human
- Type: Rabbit IgG
- Application: WB, IF, IHC, FC
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- Human Anti-FGFR3 Antibody (clone R3), mRNA (PABW-162-mRNA)
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- Species Reactivity: Human
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- Human Anti-FGFR3 Antibody, mRNA (AGTO-L016G-mRNA)
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- Species Reactivity: Human
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- Mouse Anti-FGFR3 Antibody, mRNA (AGTO-G028G-mRNA)
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- Species Reactivity: Human
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- Human Anti-FGFR3 Recombinant Antibody; Fab Fragment (HPAB-AP656-YC-F(E)) (HPAB-AP656-YC-F(E))
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- Derivation: Human phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Inhib, FuncS
Compare
- Human Anti-FGFR3 Recombinant Antibody; Fab Fragment (HPAB-AP655-YC-F(E)) (HPAB-AP655-YC-F(E))
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- Derivation: Human phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Inhib, FuncS
Compare
- Human Anti-FGFR3 Recombinant Antibody; Fab Fragment (HPAB-AP654-YC-F(E)) (HPAB-AP654-YC-F(E))
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- Derivation: Human phage display library
- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Inhib, FuncS
Compare
- Human Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-AP656-YC-S(P)) (HPAB-AP656-YC-S(P))
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- Derivation: Human phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, Inhib, FuncS
Compare
- Human Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-AP655-YC-S(P)) (HPAB-AP655-YC-S(P))
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- Derivation: Human phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, Inhib, FuncS
Compare
- Human Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-AP654-YC-S(P)) (HPAB-AP654-YC-S(P))
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- Derivation: Human phage display library
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, Inhib, FuncS
Compare
- Human Anti-FGFR3 Recombinant Antibody (HPAB-AP656-YC) (HPAB-AP656-YC)
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- Derivation: Human phage display library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Inhib, FuncS
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- Human Anti-FGFR3 Recombinant Antibody (HPAB-AP655-YC) (HPAB-AP655-YC)
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- Derivation: Human phage display library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Inhib, FuncS
Compare
- Human Anti-FGFR3 Recombinant Antibody (HPAB-AP654-YC) (HPAB-AP654-YC)
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- Derivation: Human phage display library
- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Inhib, FuncS
Compare
- Human Anti-FGFR3 Recombinant Antibody; Fab Fragment (HPAB-0150-WJ-F(E)) (HPAB-0150-WJ-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA
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- Human Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-0150-WJ-S(P)) (HPAB-0150-WJ-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
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- Human Anti-FGFR3 Recombinant Antibody (HPAB-0150-WJ) (HPAB-0150-WJ)
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- Species Reactivity: Human
- Type: Human IgG1
- Application: ELISA
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- Anti-Human FGFR3 Recombinant Antibody (TAB-285CL)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Antibody
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- aFGF-Gel immunotoxin (AGTO-L016G)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- aFGF-PE immunotoxin (AGTO-L016E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
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- Anti-FGFR3 immunotoxin (scFv)-Gel (AGTO-G028G)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Anti-FGFR3 immunotoxin (scFv)-PE (AGTO-G028E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Function study
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- Human Anti-FGFR3 Recombinant Antibody (clone PRO-055); Fab Fragment (HPAB-0161-YC-F(E))
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- Derivation: Combinatorial antibody library
- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FC, FuncS
Compare
- Human Anti-FGFR3 Recombinant Antibody (clone PRO-001); Fab Fragment (HPAB-0160-YC-F(E))
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- Derivation: Combinatorial antibody library
- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: FC, FuncS
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- Human Anti-FGFR3 Recombinant Antibody (clone Antibody 1); Fab Fragment (HPAB-0159-YC-F(E))
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human Fab
- Application: ELISA, FuncS
Compare
- Mouse Anti-FGFR3 Recombinant Antibody; Fab Fragment (HPAB-0158-YC-F(E)) (HPAB-0158-YC-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC
Compare
- Human Anti-FGFR3 Recombinant Antibody; Fab Fragment (HPAB-0157-YC-F(E)) (HPAB-0157-YC-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, IP, WB
Compare
- Human Anti-FGFR3 Recombinant Antibody (clone PRO-055); scFv Fragment (HPAB-0161-YC-S(P))
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- Derivation: Combinatorial antibody library
- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FC, FuncS
Compare
- Human Anti-FGFR3 Recombinant Antibody (clone PRO-001); scFv Fragment (HPAB-0160-YC-S(P))
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- Derivation: Combinatorial antibody library
- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: FC, FuncS
Compare
- Human Anti-FGFR3 Recombinant Antibody (clone Antibody 1); scFv Fragment (HPAB-0159-YC-S(P))
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- Derivation: Phage display library
- Species Reactivity: Human, Mouse
- Type: Human scFv
- Application: ELISA, FuncS
Compare
- Mouse Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-0158-YC-S(P)) (HPAB-0158-YC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA, FC
Compare
- Human Anti-FGFR3 Recombinant Antibody; scFv Fragment (HPAB-0157-YC-S(P)) (HPAB-0157-YC-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, IP, WB
Compare
- Human Anti-FGFR3 Recombinant Antibody (clone PRO-055) (HPAB-0161-YC)
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- Derivation: Combinatorial antibody library
- Species Reactivity: Human, Mouse
- Type: Human IgG
- Application: FC, FuncS
Compare
- Human Anti-FGFR3 Recombinant Antibody (clone PRO-001) (HPAB-0160-YC)
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- Derivation: Combinatorial antibody library
- Species Reactivity: Human, Mouse
- Type: Human IgG
- Application: FC, FuncS
Compare
- Human Anti-FGFR3 Recombinant Antibody (clone Antibody 1) (HPAB-0159-YC)
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- Species Reactivity: Human, Mouse
- Type: Human IgG
- Application: ELISA, FuncS
Compare
- Mouse Anti-FGFR3 Recombinant Antibody (HPAB-0158-YC) (HPAB-0158-YC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
Compare
- Human Anti-FGFR3 Recombinant Antibody (HPAB-0157-YC) (HPAB-0157-YC)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, IP, WB
Compare
- Anti-Human FGFR3 Recombinant Antibody Fab Fragment (15D8) (TAB-064WM-F(E))
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- Species Reactivity: Human
- Application: Neut, ELISA
Compare
- Mouse Anti-FGFR3 Recombinant Antibody; Fab Fragment (TAB-063WM-F(E)) (TAB-063WM-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, Neut, WB
Compare
- Mouse Anti-FGFR3 Recombinant Antibody; Fab Fragment (TAB-062WM-F(E)) (TAB-062WM-F(E))
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- Species Reactivity: Human
- Type: Mouse Fab
- Application: ELISA, FC, Neut, WB
Compare
- Anti-Human FGFR3 Recombinant Antibody scFv Fragment (15D8) (TAB-064WM-S(P))
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- Species Reactivity: Human
- Application: Neut, ELISA
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- Anti-Human FGFR3 Recombinant Antibody (15D8) (TAB-064WM)
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- Species Reactivity: Human
- Application: Neut, ELISA
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