I need an antibody that can neutralize human IL17A. Is this antibody suitable?

Yes, this antibody is an excellent candidate for your research. It is a recombinant, humanized IgG1-kappa antibody that specifically targets human IL17A. Our product data explicitly lists ELISA, FC, IHC and IF as validated applications.

What are the specifications of the TAB-069 antibody? I need to know its host, isotype, and purity for my experimental planning.

This is a high-quality recombinant monoclonal antibody. It is a human antibody of the IgG1 - kappa isotype, expressed in CHO cells. It specifically targets human IL17A. Furthermore, it has a high purity level of>95.0%, as determined by both RP-HPLC and SDS-PAGE analysis, ensuring reliability in your research applications.

Anti-Human IL17A Recombinant Antibody (TAB-069)

CAT#: TAB-069

Recombinant monoclonal antibody to IL17A. It is a human monoclonal antibody designed for the treatments of uveitis, rheumatoid arthritis, and psoriasis. It targets member A from the cytokine family of interleukin 17.

Tested Data Gene Expression

ELISA

Figure 1 Anti-Human IL17A Antibody (TAB-069) in ELISA

ELISA analysis of TAB-069 was performed by coating with Human IL17A Protein (No Tag). Then blocked with BSA and incubated with TAB-069. The HRP-conjugated goat anti-human IgG as a secondary antibody (1: 5000). Detection was performed using TMB substrate and stopped with sulfuric acid. The absorbances were read on a spectrophotometer at 450 nm.

Figure 2 Anti-Human IL17A Antibody (TAB-069) in WB

Western blot analysis of TAB-069 was performed with Human IL17A Protein (No Tag) in reduced condition Lane 1, Lane 2 and Lane 3 (0.1 μg, 0.3 μg and 0.6 μg respectively) onto a 12% Tris-HCl polyacrylamide gel. Proteins were transferred to a CN membrane and blocked with 5% skim milk for at least one hour. Membranes were probed with TAB-069 (2 μg/mL) and HRP-conjugated goat anti-human IgG as a secondary antibody (1: 6000). Chemiluminescent detection was performed.

Figure 3 Anti-Human IL17A Antibody (TAB-069) in DB

Dot Blot analysis of TAB-069 was performed by coating with Human IL17A Protein (No Tag).

TAB-069 incubation concentration: 2 μg/mL.
HRP goat anti-human IgG as a secondary antibody (1: 6000)

NC: Negative control PC: Positive control

❮

❯

Normal Tissue Figure 1 IHC staining of human small intestine

Immunohistochemical staining of human small intestine shows distinct positivity in peripheral leukocytes.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/ihc_selected.jpg

Normal Tissue Figure 2 Cerebral cortex

Neuronal cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_B_7_5.jpg

Normal Tissue Figure 3 Colon

Endothelial cells Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous Peripheral nerve/ganglion Staining: Low Intensity: Weak Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_8_3.jpg

Normal Tissue Figure 4 Liver

Hepatocytes Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_7_4.jpg

Normal Tissue Figure 5 Kidney

Cells in tubules Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_7_5.jpg

Normal Tissue Figure 6 Testis

Cells in seminiferous ducts Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous Leydig cells Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_4_6.jpg

Normal Tissue Figure 7 Tonsil

Germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/52258/119541_A_4_8.jpg

RNA Expression Figure 8 RNA cell line category: Group enriched (Karpas-707, U-266/84)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000112115-IL17A

❮

❯

Specifications

Immunogen
HuIL-17 coupled 10 KLH mixed 1:1 with huIL-17 in Gerbu adjuvant.

Host Species
Human

Derivation
Human

Type
IgG1 - kappa

Specificity
Tested positive against native human antigen.

Species Reactivity
Human

Applications
IF, IHC, ELISA, FC

MW
147.94 kDa

Related Disease
Psoriatic arthritis (PSA)

Product Property

Purity
>95.0% as determined by Analysis by RP-HPLC & analysis by SDS-PAGE.

Storage
At -20°C for one year.

Applications

Application Notes
The IL17A antibody has been reported in applications of Immunofluorescence, Immunohistochemistry, Enzyme-linked Immunosorbent Assay, Flow Cytometry. FC: The isotype, IL17RA AlexaFluor 647 and IL17RC AlexaFluor 488 antibodies were used at 4mg/ml and 10mg/ml respectively for FACs analysis.

Target

Alternative Names
Interleukin 17A

Gene ID
3605

UniProt ID
Q16552

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for TAB-069. Click the button above to contact us or submit your feedback about this product.

Breast cancer biomarkers at key points during disease progression

Great for Functional Studies

This anti-IL17A antibody (TAB-069) is excellent. I'm running many assays, and the product data confirms it's validated for ELISA, FC, IF, and IHC. The>95% purity and CHO expression are key quality markers for a functional-grade antibody.

Versatile Humanized Antibody

I'm impressed by the range of applications for this antibody. It's listed for ELISA, FC, IF, and IHC. It's a humanized IgG1-kappa derived from a mouse source, which is perfect for my research on human IL17A signaling. It performed beautifully in flow cytometry (FC).

Q&As

I need an antibody that can neutralize human IL17A. Is this antibody suitable?

A: Yes, this antibody is an excellent candidate for your research. It is a recombinant, humanized IgG1-kappa antibody that specifically targets human IL17A. Our product data explicitly lists ELISA, FC, IHC and IF as validated applications.
What are the specifications of the TAB-069 antibody? I need to know its host, isotype, and purity for my experimental planning.

A: This is a high-quality recombinant monoclonal antibody. It is a human antibody of the IgG1 - kappa isotype, expressed in CHO cells. It specifically targets human IL17A. Furthermore, it has a high purity level of>95.0%, as determined by both RP-HPLC and SDS-PAGE analysis, ensuring reliability in your research applications.

View the frequently asked questions answered by Creative Biolabs Support.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Biosimilar Overview

Please refer to Secukinumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Secukinumab.

Related Diseases

Inflammatory Bowel Diseases

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-069.pdf

MSDS

MSDS - TAB-069.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

Protocol & Troubleshooting

Immunofluorescence (IF)

Immunohistochemistry (IHC)

We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.

See other products for "IL17A"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
MOB-1390z	Mouse Anti-IL17A Recombinant Antibody (clone 22B9)	FuncS	Mouse IgG2b

CAT	Product Name	Application	Type
TAB-H57	Anti-Human IL17A Recombinant Antibody (Perakizumab)	WB, ELISA, IP, FC, FuncS, Neut, IF	IgG1 - kappa

CAT	Product Name	Application	Type
TAB-H08	Anti-Human IL17A/IL17F Recombinant Antibody (TAB-H08)	ELISA, FC, IP, FuncS, IF, Neut, WB	IgG1 - kappa

CAT	Product Name	Application	Type
TAB-399CL	Human Anti-IL17A Recombinant Antibody (TAB-399CL)	ELISA	Human IgG

CAT	Product Name	Application	Type
PABL-237	Human Anti-IL17A Recombinant Antibody (clone CNTO7357)	WB, IHC, FuncS	Human IgG

CAT	Product Name	Application	Type
PABL-238	Human Anti-IL17A Recombinant Antibody (clone Fab6785)	WB, ELISA, FuncS	Human IgG

CAT	Product Name	Application	Type
PSBL-237	Human Anti-IL17A Recombinant Antibody (clone CNTO7357); scFv Fragment	WB, IHC, FuncS	Human scFv

CAT	Product Name	Application	Type
PSBL-238	Human Anti-IL17A Recombinant Antibody (clone Fab6785); scFv Fragment	WB, ELISA, FuncS	Human scFv

CAT	Product Name	Application	Type
PFBL-237	Human Anti-IL17A Recombinant Antibody (clone CNTO7357); Fab Fragment	WB, IHC, FuncS	Human Fab

CAT	Product Name	Application	Type
PFBL-238	Human Anti-IL17A Recombinant Antibody (clone Fab6785); Fab Fragment	WB, ELISA, FuncS	Human Fab

CAT	Product Name	Application	Type
PABW-176	Human Anti-IL17A Recombinant Antibody (PABW-176)	Neut, ELISA, WB	Human IgG

CAT	Product Name	Application	Type
PFBW-176	Human Anti-IL17A Recombinant Antibody; Fab Fragment (PFBW-176)	Neut, ELISA, WB	Human Fab

CAT	Product Name	Application	Type
PSBW-176	Human Anti-IL17A Recombinant Antibody; scFv Fragment (PSBW-176)	Neut, ELISA, WB	Human scFv

CAT	Product Name	Application	Type
TAB-030ZJ	Mouse Anti-IL17A Recombinant Antibody (TAB-030ZJ)	ELISA, Neut	Mouse IgG

CAT	Product Name	Application	Type
TAB-048ZJ	Human Anti-IL17A Recombinant Antibody (TAB-048ZJ)	ELISA, Neut	Humanized antibody

CAT	Product Name	Application	Type
TAB-078ZJ	Human Anti-IL17A Recombinant Antibody (TAB-078ZJ)	ELISA, Block, Neut	Human antibody

CAT	Product Name	Application	Type
TAB-079ZJ	Human Anti-IL17A Recombinant Antibody (TAB-079ZJ)	ELISA, Block, Neut	Human IgG1

CAT	Product Name	Application	Type
TAB-080ZJ	Human Anti-IL17A Recombinant Antibody (TAB-080ZJ)	ELISA, Block, Neut	Human antibody

CAT	Product Name	Application	Type
TAB-030ZJ-S(P)	Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-030ZJ-S(P))	ELISA, Neut	Mouse scFv

CAT	Product Name	Application	Type
TAB-048ZJ-S(P)	Human Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-048ZJ-S(P))	ELISA, Neut	Human scFv

CAT	Product Name	Application	Type
TAB-078ZJ-S(P)	Human Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-078ZJ-S(P))	ELISA, Block, Neut	Human scFv

CAT	Product Name	Application	Type
TAB-079ZJ-S(P)	Human Anti-IL17A Recombinant Antibody; scFv Fragment (TAB-079ZJ-S(P))	ELISA, Block, Neut	Human scFv

CAT	Product Name	Application	Type
TAB-030ZJ-F(E)	Mouse Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-030ZJ-F(E))	ELISA, Neut	Mouse Fab

CAT	Product Name	Application	Type
TAB-048ZJ-F(E)	Human Anti-IL17A Recombinant Antibody; Fab Fragment (TAB-048ZJ-F(E))	ELISA, Neut	Humanized Fab

CAT	Product Name	Application	Type
Gly-077LC	Recombinant Anti-Human IL17A Antibody (Fc glycosylation)	ELISA	Humanized antibody

CAT	Product Name	Application	Type
MOB-1196MZ	Recombinant Mouse Anti-Human IL17A Antibody (clone 2I7)	WB	Mouse antibody

CAT	Product Name	Application	Type
BRD-0289MZ	Chicken Anti-Interleukin-17a Polyclonal IgY	Indirect ELISA, WB	Chicken antibody

CAT	Product Name	Application	Type
NEUT-1202CQ	Mouse Anti-IL17A Recombinant Antibody (NEUT-1202CQ)	Neut	Mouse IgG2a

CAT	Product Name	Application	Type
NEUT-1203CQ	Mouse Anti-IL17A Recombinant Antibody (NEUT-1203CQ)	Neut	Mouse IgG1

CAT	Product Name	Application	Type
NEUT-1204CQ	Mouse Anti-IL17A Recombinant Antibody (clone 403D10.01)	Neut, FC	Mouse IgG1

CAT	Product Name	Application	Type
NEUT-1205CQ	Mouse Anti-IL17A Recombinant Antibody (clone 408H6.01)	Neut, ELISA, FC	Mouse IgG2a

CAT	Product Name	Application	Type
NEUT-1206CQ	Mouse Anti-IL17A Recombinant Antibody (clone 409H7.05)	Neut, FC	Mouse IgG1

CAT	Product Name	Application	Type
HPAB-0061-YC-S(P)	Human Anti-IL17A Recombinant Antibody; scFv Fragment (HPAB-0061-YC-S(P))	ELISA, Neut	Humanized scFv

CAT	Product Name	Application	Type
HPAB-0063-YC-S(P)	Human Anti-IL17A Recombinant Antibody (clone Antibody 7); scFv Fragment	FuncS	Human scFv

CAT	Product Name	Application	Type
HPAB-0061-YC-F(E)	Human Anti-IL17A Recombinant Antibody; Fab Fragment (HPAB-0061-YC-F(E))	ELISA, Neut	Humanized Fab

CAT	Product Name	Application	Type
HPAB-0063-YC-F(E)	Human Anti-IL17A Recombinant Antibody (clone Antibody 7); Fab Fragment	FuncS	Human Fab

CAT	Product Name	Application	Type
NS-042CN	Mouse Anti-IL17A Recombinant Antibody (NS-042CN)	ELISA, FC	Mouse IgG

CAT	Product Name	Application	Type
NS-042CN-F(E)	Mouse Anti-IL17A Recombinant Antibody; Fab Fragment (NS-042CN-F(E))	ELISA, FC	Mouse Fab

CAT	Product Name	Application	Type
NS-042CN-S(P)	Mouse Anti-IL17A Recombinant Antibody; scFv Fragment (NS-042CN-S(P))	ELISA, FC	Mouse scFv

CAT	Product Name	Application	Type
AFC-TAB-458CQ	Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-458CQ)	ELISA, IHC, FC, IP, IF, Inhib	ADCC enhanced antibody

CAT	Product Name	Application	Type
AFC-TAB-069	Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-069)	FC, IP, ELISA, Neut, FuncS, IF	ADCC enhanced antibody

CAT	Product Name	Application	Type
AFC-TAB-H08	Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H08)	ELISA, FC, IP, FuncS, IF, Neut	ADCC enhanced antibody

CAT	Product Name	Application	Type
AFC-TAB-H57	Afuco™ Anti-IL17A ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-H57)	ELISA, IP, FC, FuncS, Neut	ADCC enhanced antibody

CAT	Product Name	Application	Type
VS-0424-XY147	AbPlus™ Anti-IL17A Magnetic Beads (41809)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-0225-XY130	CytoStream™ Mouse Anti-IL17A Recombinant Antibody (VS-0225-XY130)	FC	Mouse IgG1, kappa

CAT	Product Name	Application	Type
VS-0325-FY96	Human Anti-IL17A (clone Antibody 7) scFv-Fc Chimera	ELISA, Inhib	Human IgG1, scFv-Fc

CAT	Product Name	Application	Type
VS-0525-XY3489	Anti-IL17A Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0525-XY3490	Anti-Human IL17A Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0525-XY3491	Anti-Mouse IL17A Immunohistochemistry Kit	IHC

CAT	Product Name	Application	Type
VS-0625-YC167	Recombinant Anti-IL17A Eliminating Antibody, pH-Sensitive (VS-0625-YC167)	Antigen-Sweeping In Vivo.	Rat IgG1 kappa

CAT	Product Name	Application	Type
VS-0825-YC175	SmartAb™ Recombinant Anti-IL17A pH-dependent Antibody (VS-0825-YC175)	IF, IHC, ELISA, FC	Human IgG1 kappa

Specific Inquiry

Size:

Conjugation:

Endotoxin:

Purity:

Formats:

Isotype Switching:

Fc Engineering:

Modalities:

Add to compare

Request
Custom Production

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Figure 3 Anti-ANGPT2 Therapeutic Antibody (TAB-769) in ELISA

Anti-ANGPT2 Recombinant Antibody (CAT# TAB-769)
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

Figure 2 Anti-Human TNF Antibody (TAB-010) in ELISA

Anti-Human TNF Recombinant Antibody (TAB-010) (CAT# TAB-010)
Application: WB, FC, IP, ELISA, Neut, FuncS, IF

Figure 5 Anti-Human CD40L Recombinant Antibody (TAB-027) in ELISA

Anti-Human CD40L Recombinant Antibody (TAB-027) (CAT# TAB-027)
Application: IF, IP, Neut, FuncS, ELISA, FC, ICC

Figure 2 Anti-Human CD2 Antibody (TAB-104) in WB

Anti-Human CD2 Recombinant Antibody (TAB-104) (CAT# TAB-104)
Application: ELISA, IP, FC, FuncS, Neut, IF, ICC

Figure 1 Anti-Human IL13 Antibody (TAB-219) in ELISA

Anti-Human IL13 Recombinant Antibody (TAB-219) (CAT# TAB-219)
Application: ELISA, Neut, IF, IP, FC, FuncS

Figure 4 Anti-Human EPCAM Recombinant Antibody (TAB-235CL) in ELISA

Human Anti-Human EPCAM Recombinant Antibody (3622W94) (CAT# TAB-235CL)
Application: Cyt, FC

Figure 1 Trastuzumab (TP-083CL) in SPR

Human Anti-ERBB2 Rcombinant Antibody (TP-083CL) (CAT# TP-083CL)
Application:

Figure 3 Mouse Anti-VEGF Recombinant Antibody (PABW-130) in ELISA

Mouse Anti-VEGF Recombinant Antibody (clone A4.6.1) (CAT# PABW-130)
Application: Neut, ELISA, Inhib, ICC, WB

Figure 5 Recombinant Human Anti-EBV BLLF1 Antibody (PABZ-138) in DB

Recombinant Human Anti-EBV BLLF1 Antibody (72A1) (CAT# PABZ-138)
Application: Neut, ELISA

Figure 2 Anti-Human CD47 Recombinant Antibody (TAB-303LC) in ELISA

Human Anti-CD47 Recombinant Antibody (TAB-303LC) (CAT# TAB-303LC)
Application: ELISA

Figure 2 Anti-FGFR1 Therapeutic Antibody (FR1-H7) (TAB-052WM) in ELISA

Anti-Human FGFR1 Recombinant Antibody (FR1-H7) (CAT# TAB-052WM)
Application: ELISA, Neut

Figure 2 Anti-Human TEM7R Recombinant Antibody (TAB-577CT) in HPLC

Human Anti-PLXDC2 Recombinant Antibody (TAB-577CT) (CAT# TAB-577CT)
Application: ELISA, FC, IHC, IF

Figure 4 Anti-Human SNCA Antibody (TAB-0750CLV) in HPLC

Mouse Anti-SNCA Recombinant Antibody (TAB-0750CLV) (CAT# TAB-0750CLV)
Application: ELISA

Figure 2 Human Anti-IL15 Recombinant Antibody (HPAB-0238-YC) in WB

Human Anti-IL15 Recombinant Antibody (HPAB-0238-YC) (CAT# HPAB-0238-YC)
Application: ELISA, FC, Inhib, FuncS

Figure 2 Human Anti-SLC30A8 Recombinant Antibody (clone C22) (HPAB-0040-CN) in SDS-PAGE

Human Anti-SLC30A8 Recombinant Antibody (clone C22) (CAT# HPAB-0040-CN)
Application: ELISA, WB, IHC

Figure 2 Human IgG1, lambda Isotype Control Antibody (MOB-173CQ) in HPLC

Human IgG1, lambda Isotype Control Antibody (CAT# MOB-173CQ)
Application: ELISA

Figure 3 Anti-LAM Recombinant Fab Fragment Antibody (PFBC-542) in WB

Recombinant Human Anti-LAM Antibody Fab Fragment (PFBC-542) (CAT# PFBC-542)
Application: ELISA, WB

Figure 2 Mouse Anti-FSTL3 Recombinant Antibody (HPAB-N0094-YC) in HPLC

Mouse Anti-FSTL3 Recombinant Antibody (HPAB-N0094-YC) (CAT# HPAB-N0094-YC)
Application: Neut, WB

Figure 5 Human Anti-IAV H3N2 HA Recombinant Antibody (PABJ-0152) in Dot Blot

Human Anti-IAV H3N2 HA Recombinant Antibody (clone S5V2-29) (CAT# PABJ-0152)
Application: ELISA, Neut, FuncS

Figure 1 Mouse Anti-PIK3CA H1047R Recombinant Antibody (MOB-0202F) in IHC

Mouse Anti-PIK3CA H1047R Recombinant Antibody (MOB-0202F) (CAT# MOB-0202F)
Application: IHC-P, IF

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.