Recombinant monoclonal antibody to VEGF Receptor 2. Ramucirumab (IMC-1121B) is a fully human monoclonal antibody (IgG1) for the treatment of solid tumors. It is directed against the vascular endothelial growth factor receptor 2 (VEGFR2). By binding to VEGFR2 it works as a receptor antagonist blocking the binding of vascular endothelial growth factor (VEGF) to VEGFR2. VEGFR2 is known to mediate the majority of the downstream effects of VEGF in angiogenesis.
Host: Human
Isotype: IgG1 - kappa
Applications: FC, IHC
Figure 1 Impact of anti-VEGFR2 blockade on PBMCs in vitro.
VEGFR2 expression in several T-cell subsets.
Tada, Y., Togashi, Y., Kotani, D., Kuwata, T., Sato, E., Kawazoe, A., ... & Shitara, K. (2018). Targeting VEGFR2 with Ramucirumab strongly impacts effector/activated regulatory T cells and CD8+ T cells in the tumor microenvironment. Journal for immunotherapy of cancer, 6(1), 1-14.
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
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Afuco™ Anti-KDR ADCC Recombinant Antibody (Ramucirumab), ADCC EnhancedThis product is an ADCC enhanced antibody produced by our Afuco™ platform. Recombinant monoclonal antibody to VEGF Receptor 2. Ramucirumab (IMC-1121B) is a fully human monoclonal antibody (IgG1) for the treatment of solid tumors. It is directed against the vascular endothelial growth factor receptor 2 (VEGFR2). By binding to VEGFR2 it works as a receptor antagonist blocking the binding of vascular endothelial growth factor (VEGF) to VEGFR2. VEGFR2 is known to mediate the majority of the downstream effects of VEGF in angiogenesis.
CAT | Product Name | Application | Type |
IAB-B066(A) | Recombinant Anti-human KDR Intrabody [(D-Arg)9] | FC, IF, FuncS | scFv-(D-Arg)9 |
IAB-B066(G) | Recombinant Anti-human KDR Intrabody [+36 GFP] | CO-IP, FuncS | scFv-(+36GFP) |
IAB-B066(T) | Recombinant Anti-human KDR Intrabody [Tat] | IF, ELISA, FuncS | scFv-Tat |
CAT | Product Name | Application | Type |
TAB-202 | Humanized Anti-KDR Recombinant Antibody (clone Alacizumab); di - Fab' Fragment | IF, IP, Neut, FuncS, ELISA, FC, ICC | Humanized (from mouse) di - Fab' |
TAB-411CQ | Anti-Human KDR Recombinant Antibody (HLX06) | ELISA | Humanized antibody |
TAB-411CQ-S(P) | Anti-Human KDR Recombinant Antibody scFv Fragment (HLX06) | ELISA | Humanized antibody |
TAB-411CQ-F(E) | Anti-Human KDR Recombinant Antibody Fab Fragment (HLX06) | ELISA | Humanized antibody |
CAT | Product Name | Application | Type |
AGTO-G047E | Anti-KDR immunotoxin (IgG1)-PE | Cytotoxicity assay, Function study |
CAT | Product Name | Application | Type |
TAB-0298CL-F(E) | Human Anti-KDR Recombinant Antibody; Fab Fragment (TAB-0298CL-F(E)) | FC, ELISA, Inhib, Neut, FuncS | Human Fab |
TAB-0299CL-F(E) | Human Anti-KDR Recombinant Antibody; Fab Fragment (TAB-0299CL-F(E)) | WB, FC, Inhib, Neut | Human Fab |
TAB-325CQ-F(E) | Human Anti-KDR Recombinant Antibody; Fab Fragment (TAB-325CQ-F(E)) | ELISA, FC | Human Fab |
TAB-329CQ-F(E) | Human Anti-KDR Recombinant Antibody; Fab Fragment (TAB-329CQ-F(E)) | ELISA, WB, Neut | Human Fab |
TAB-330CQ-F(E) | Mouse Anti-KDR Recombinant Antibody; Fab Fragment (TAB-330CQ-F(E)) | ELISA, WB, Neut | Mouse Fab |
CAT | Product Name | Application | Type |
PSBC-204 | Mouse Anti-KDR Recombinant Antibody (clone mAb6.64); scFv Fragment | Neut, Block | Mouse scFv |
HPAB-N0154-YC-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-N0154-YC-S(P)) | ELISA, Inhib | Mouse scFv |
HPAB-0016-YJ-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-0016-YJ-S(P)) | RIA, ELISA | Mouse scFv |
HPAB-0567-WJ-S(P) | Human Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-0567-WJ-S(P)) | ELISA, FC, WB | Human scFv |
HPAB-0476-FY-S(P) | Mouse Anti-KDR Recombinant Antibody; scFv Fragment (HPAB-0476-FY-S(P)) | Inhib | Mouse scFv |
CAT | Product Name | Application | Type |
TAB-326CQ | Rat Anti-Kdr Recombinant Antibody (TAB-326CQ) | ELISA, IHC | Rat IgG |
TAB-331CQ | Anti-Human KDR Recombinant Antibody (6.64) | IHC | |
TAB-332CQ | Anti-Human KDR Recombinant Antibody (4.13) | ELISA, FC, IHC | |
TAB-326CQ-F(E) | Rat Anti-Kdr Recombinant Antibody; Fab Fragment (TAB-326CQ-F(E)) | ELISA, FC, WB | Rat Fab |
TAB-331CQ-F(E) | Anti-Human KDR Recombinant Antibody Fab Fragment (6.64) | ELISA, FC, IHC |
CAT | Product Name | Application | Type |
BRD-0624MZ | Chicken Anti-VEGFR-2 Polyclonal IgY | IHC, WB | Chicken antibody |
BRD-0709MZ | Chicken Anti-KDR Polyclonal IgY | WB | Chicken antibody |
CAT | Product Name | Application | Type |
NEUT-1619CQ | Recombinant Mouse Anti-KDR Antibody (23B31) | WB, IP, FC, Neut | |
NEUT-1620CQ | Recombinant Rat Anti-Kdr Antibody (CBL840) | ELISA(Cap), Neut | IgG2a |
NEUT-1621CQ | Recombinant Rat Anti-Kdr Antibody (CBL880) | Neut, WB | IgG2 |
NEUT-1622CQ | Recombinant Mouse Anti-KDR Antibody (6B11) | WB, Neut | IgG1 |
NEUT-1623CQ | Recombinant Mouse Anti-KDR Antibody (CBL505) | FC, CyTOF, Neut | IgG1 |
CAT | Product Name | Application | Type |
MOR-1927 | Hi-Affi™ Recombinant Rabbit Anti-KDR Monoclonal Antibody (DS1927AB) | IHC-P | IgG |
CAT | Product Name | Application | Type |
HPAB-0097-YC | Rabbit Anti-KDR Recombinant Antibody (HPAB-0097-YC) | ELISA, FuncS | Rabbit IgG |
HPAB-0098-YC | Rabbit Anti-KDR Recombinant Antibody (HPAB-0098-YC) | ELISA, FuncS | Rabbit IgG |
HPAB-0099-YC | Rabbit Anti-KDR Recombinant Antibody (HPAB-0099-YC) | ELISA, FuncS | Rabbit IgG |
MRO-1580-CN | Recombinant Rabbit Anti-KDR Monoclonal Antibody (SU03-42) | WB, IF, IHC, IP | Rabbit IgG |
HPAB-0251-FY | Human Anti-KDR Recombinant Antibody (clone 043HAb-1) | ELISA | Human IgG1 |
CAT | Product Name | Application | Type |
AFC-TAB-079 | Afuco™ Anti-KDR ADCC Recombinant Antibody (Ramucirumab), ADCC Enhanced | IP, IF, FuncS, FC, Neut, ELISA | ADCC enhanced antibody |
CAT | Product Name | Application | Type |
HPAB-M0126-YC-F(E) | Human Anti-KDR Recombinant Antibody (clone RD); Fab Fragment | ELISA | Human Fab |
HPAB-M0127-YC-F(E) | Human Anti-KDR Recombinant Antibody (clone PCABHL3); Fab Fragment | ELISA, Inhib | Humanized Fab |
HPAB-M0128-YC-F(E) | Human Anti-KDR Recombinant Antibody (clone PCABHL5); Fab Fragment | ELISA, Inhib | Humanized Fab |
HPAB-M0129-YC-F(E) | Human Anti-KDR Recombinant Antibody (clone PCABHL7); Fab Fragment | ELISA, Inhib | Humanized Fab |
HPAB-M0130-YC-F(E) | Human Anti-KDR Recombinant Antibody (clone H15PCABL); Fab Fragment | ELISA, Inhib | Humanized Fab |
CAT | Product Name | Application | Type |
HPAB-0298-YJ-VHH | Recombinant Human Anti-KDR Nano Antibody (NTV1) | Inhib | Human VHH |
CAT | Product Name | Application | Type |
MHC-YF304 | A*24:02/Human VEGFR (SYGVLLWEI) MHC Monomer | MHC Multimer | |
MHC-YF772 | H-2Db/Human VEGFR2/KDR fragment 1 (FSNSTNDILI) MHC Pentamer | FCM |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.