Anti-Human VEGF Receptor 2 Recombinant Antibody (TAB-079) (CAT#: TAB-079)

Recombinant monoclonal antibody to VEGF Receptor 2. It is a fully human monoclonal antibody (IgG1) for the treatment of solid tumors. It is directed against the vascular endothelial growth factor receptor 2 (VEGFR2). By binding to VEGFR2 it works as a receptor antagonist blocking the binding of vascular endothelial growth factor (VEGF) to VEGFR2. VEGFR2 is known to mediate the majority of the downstream effects of VEGF in angiogenesis.

Specific Inquiry
  • Size:
  • Conjugation:
  • Endotoxin:
  • Purity:
  • Formats:
  • Isotype Switching:
  • Fc Engineering:
  • Modalities:
  • Gene Expression
  • Datasheet
  • MSDS
  • COA
Subcellular Location
Normal Tissue
RNA Expression

Specifications

  • Immunogen
  • The details of the immunogen for this antibody are not available.
  • Host Species
  • Human
  • Derivation
  • Human
  • Type
  • IgG1 - kappa
  • Specificity
  • Tested positive against native human antigen.
  • Species Reactivity
  • Human
  • Applications
  • FC, IHC
  • MW
  • 143.6 kDa
  • Related Disease
  • Non-small cell lung cancers (NSCLC)

Product Property

  • Purity
  • >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Storage
  • 4°C. For long term storage, aliquot and store at -20°C. Repeated thawing and freezing must be avoided.

Applications

  • Application Notes
  • The VEGF Receptor 2 antibody has been reported in applications of Immunohistochemistry, Flow Cytometry.

Target

  • Alternative Names
  • Ramucirumab;Cyramza;947687-13-0;IMC-1121B;LY3009806;IMC-1121B;Cyramza;KDR;kinase insert domain receptor (a type III receptor tyrosine kinase);vascular endothelial growth factor receptor 2;CD309;FLK1;VEGFR;VEGFR2;soluble VEGFR2;fetal liver kinase 1;fetal l

Related Resources

  • Biosimilar Overview
Please refer to Ramucirumab Overview to learn more about the mechanism of action, clinical projects, and approved drugs of Ramucirumab.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

Download resources about recombinant antibody development and antibody engineering to boost your research.

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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