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    Anti-Human TEK Recombinant Antibody (CAT#: TAB-597CL)

    Recombinant Human monoclonal antibody expressed in CHO binding to Human TEK. The antibodiess that bind to Tie2 are useful for the treatment of disorders associated with one or more Tie2 biological activities including angiogenesis. Aberrant angiogenesis is associated with several disease conditions including, proliferative retinopathies, rheumatoid arthritis and psoriasis.

    Specific Inquiry
    • Size:

    • Conjugation:

    • Endotoxin:

    • Purity:

    • Formats:

    • Isotype Switching:

    • Fc Engineering:

    • Modalities:

    Custom Production

    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

    Sequences:
    Isotype :
    Purity :
    Endotoxin :
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    Other Requirements:
    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-2 OS
    Figure 1 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane & centriolar satellites.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73265/1607_D9_2_selected.jpg
    Figure 2 IHC staining of human testis
    Figure 2 IHC staining of human testis
    (Immunohistochemical staining of human testis shows strong cytoplasmic positivity in cells of seminiferus ducts.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10359/ihc_selected.jpg
    Figure 3 IF staining of human cell line AF22
    Figure 3 IF staining of human cell line AF22
    (Immunofluorescent staining of human cell line AF22 shows localization to plasma membrane & centriolar satellites.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73265/1687_H4_1_red_green.jpg
    Figure 4 IF staining of human cell line BJ
    Figure 4 IF staining of human cell line BJ
    (Immunofluorescent staining of human cell line BJ shows localization to plasma membrane & centriolar satellites.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73265/1667_D9_1_red_green.jpg
    Normal Tissue
    Figure 5 Colon
    Figure 5 Colon
    (Endothelial cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous
    Peripheral nerve/ganglion
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10359/24108_A_8_3.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Elongated or late spermatids
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Leydig cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%
    Pachytene spermatocytes
    Staining: High
    Intensity: Strong
    Quantity: 75%-25%
    Round or early spermatids
    Staining: High
    Intensity: Strong
    Quantity:>75%
    Sertoli cells
    Staining: Medium
    Intensity: Moderate
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/10359/24108_A_6_6.jpg
    RNA Expression
    Figure 7 RNA cell line category: Group enriched (HUVEC TERT2, NTERA-2, TIME)
    Figure 7 RNA cell line category: Group enriched (HUVEC TERT2, NTERA-2, TIME)
    (Cell lines ordered by descending RNA expression order.)
    * https://v21.proteinatlas.org/ENSG00000120156-TEK
    Figure 7 RNA cell line category: Group enriched (HUVEC TERT2, NTERA-2, TIME)
    Figure 7 RNA cell line category: Group enriched (HUVEC TERT2, NTERA-2, TIME)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000120156-TEK

    Specifications

    • Host Species
    • Human
    • Type
    • Antibody
    • Species Reactivity
    • Human
    • Related Disease
    • Proliferative Retinopathies; Rheumatoid Arthritis; Psoriasis

    Product Property

    • Purity
    • >95% (SDS-PAGE)
    • Storage
    • Store the antibody (in aliquots) at -20°C. Avoid repeated freezing and thawing of samples.

    Target

    • Alternative Names
    • TEK; TEK tyrosine kinase, endothelial; TIE2; VMCM; TIE-2; VMCM1; CD202B; angiopoietin-1 receptor; endothelial tyrosine kinase; tyrosine-protein kinase receptor TEK; tunica interna endothelial cell kinase; tyrosine-protein kinase receptor TIE-2; tyrosine k

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

    Download resources about recombinant antibody development and antibody engineering to boost your research.

    See other products for "TEK"

    Select a product category from the dropdown menu below to view related products.
    Please select product type
    Fab Antibody Products Intrabody Products Human Antibody Products IgG Antibody Products Chicken IgY Antibody Products Blocking Antibody Products Rabbit Monoclonal Antibody Products ScFv Antibody Products ScFv-Fc Chimera Products Extracellular Vesicle (EV) Antibody Products
    CAT Product Name Application Type
    DrMAB-1030 Mouse Anti-TEK Recombinant Antibody (clone YC183); Fab Fragment ELISA Mouse Fab
    HPAB-0066-YJ-F(E) Recombinant Mouse Anti-TEK Antibody Fab Fragment (12H8) Immunoassay, WB Mouse Fab
    HPAB-0418-WJ-F(E) Human Anti-TEK Recombinant Antibody; Fab Fragment (HPAB-0418-WJ-F(E)) ELISA, FC Human Fab
    HPAB-S0139-YC-F(E) Mouse Anti-TEK Recombinant Antibody (clone 12H8); Fab Fragment ELISA, Antagonist Mouse Fab
    HPAB-S0140-YC-F(E) Mouse Anti-TEK Recombinant Antibody (clone 6A3); Fab Fragment ELISA, Antagonist Mouse Fab

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