CytoStream™ Armenian Hamster Anti-CCL2 Recombinant Antibody (clone 2H5)

Name: CytoStream™ Armenian Hamster Anti-CCL2 Recombinant Antibody (clone 2H5)
SKU: VS-0225-XY9
Rating: 5 (1 reviews)

CAT#: VS-0225-XY9

This Armenian Hamster-derived antibody, targeting CCL2, exhibits excellent reactivity with both mouse and rat samples. Designed for use in a range of applications, including ELISA, flow cytometry (FC), and neutralization assays (Neut), it provides valuable insights into CCL2-mediated immune signaling. Its versatility across multiple techniques ensures reliable results, making it an indispensable tool for investigating inflammatory processes and immune modulation in pre-clinical studies.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line BJ

Immunofluorescent staining of human cell line BJ shows localization to the Golgi apparatus.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19163/1742_B4_8_cr580492c5c7769_selected.jpg

Subcellular Location Figure 2 IHC staining of human stomach

Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in dot like pattern in glandular cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19163/ihc_selected.jpg

Subcellular Location Figure 3 IHC staining of human appendix

Immunohistochemical staining of human appendix shows strong cytoplasmic positivity in glandular cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13676/29298_A_2_2_selected.jpg

Subcellular Location Figure 4 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19163/182_D1_1_blue_red_green.jpg

Normal Tissue Figure 5 Cerebral cortex

Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13676/29298_B_9_5.jpg

Normal Tissue Figure 6 Colon

Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13676/29298_A_8_3.jpg

Normal Tissue Figure 7 Kidney

Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13676/29298_A_7_5.jpg

RNA Expression Figure 8 RNA cell line category: Group enriched (BJ hTERT+, HMC-1)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000108691-CCL2

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Specifications

Host Species
Armenian Hamster

Type
Armenian Hamster IgG1, kappa

Specificity
CCL2

Species Reactivity
Mouse, Rat

Clone
2H5

Applications
ELISA, FC, Neut

Product Property

Purification
Protein A purified

Purity
>95%, determined by SDS-PAGE

Format
Liquid

Buffer
PBS

Preservative
Sodium azide

Storage
Store at 4°C for short-term storage and at -20°C for long-term storage. Avoid repeated freeze-thaw cycles.

Target

Alternative Names
CCL2; C-C motif chemokine 2; Chemokine (C-C motif) ligand 2; MCAF; SCYA2

Gene ID
6347

UniProt ID
P13500

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Related Diseases

Rheumatoid Arthritis

Related Signaling Pathways

TNF Signaling Pathway

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - VS-0225-XY9.pdf

MSDS

MSDS - VS-0225-XY9.pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

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