Human Anti-CD37 Recombinant Antibody; Fab Fragment (HPAB-1045-FY-F(E)) (CAT#: HPAB-1045-FY-F(E))
HPAB-1045-FY is a recombinant humanized antibody that targets CD37. HPAB-1045-FY-F(E) antibody is the Fab fragment antibody form of HPAB-1045-FY antibody. Fab fragments, the antigen-binding domains of an antibody molecule, consist of two amino acid chains composed of VH+CH1 and VL+CL domains.
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We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
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Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEL
(Immunofluorescent staining of human cell line HEL shows localization to plasma membrane & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32120/1848_F10_26_cr5abb8def07051_selected.jpg
(Immunofluorescent staining of human cell line HEL shows localization to plasma membrane & the Golgi apparatus.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32120/1848_F10_26_cr5abb8def07051_selected.jpg
Figure 2 Tonsil
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32120/116092_A_5_8_val_selected.jpg
(High expression)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32120/116092_A_5_8_val_selected.jpg
Figure 3 Colon
(Enterocytes - Mucosal lymphoid cells Staining: Medium Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2492/6132_A_9_3.jpg
(Enterocytes - Mucosal lymphoid cells Staining: Medium Intensity: Strong)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2492/6132_A_9_3.jpg
Figure 4 Lymph node
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2492/6132_A_7_8.jpg
(Germinal center cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous Non-germinal center cells Staining: Low Intensity: Moderate Quantity: <25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/2492/6132_A_7_8.jpg
Figure 5 Spleen
(Cells in white pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32120/116092_B_8_4.jpg
(Cells in white pulp Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32120/116092_B_8_4.jpg
Figure 6 RNA cell line category: Cell line enhanced (Daudi, HMC-1, RPMI-8226, THP-1, U-698, U-937)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104894-CD37
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000104894-CD37
Specifications
- Host Species
- Human
- Derivation
- Humanized
- Type
- Humanized Fab
- Specificity
- Human CD37
- Species Reactivity
- Human
- Applications
- FC, ELISA
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- CD37 Molecule; Tetraspanin-26; CD37 Antigen; Tspan-26; TSPAN26; Cell Differentiation Antigen 37; Leukocyte Surface Antigen CD37; Leukocyte Antigen CD37; GP52-40
- Gene ID
- 951
- UniProt ID
- P11049
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Biparatopic Antibodies
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-904 | Anti-Human CD37 Recombinant Antibody (Otlertuzumab) | ELISA, IP, FC, FuncS, Neut, IF, ICC | VH - V-kappa - CH2 - CH3 |
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