Human Anti-F8 Recombinant Antibody (clone KM38); Fab Fragment
CAT#: FAMAB-0201JF-F(E)
Recombinant monoclonal antibody specially binds to A3-C1 domains of factor VIII. This human anti-F8 antibody (KM38) is not directed against amino acid residues E1649-R1689, a recently described epitope for factor VIII inhibitors in the acidic region at the amino-terminus of the factor VIII light chain. The epitope of this product overlaps with that of antibody CLB-CAg 12, a noninhibitory mAb directed against the A3-C1 domains of factor VIII.
Gene Expression
Normal Tissue
Figure 1 Colon
Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_7_3.jpg
Normal Tissue
Figure 2 Kidney
Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_7_5.jpg
Normal Tissue
Figure 3 Testis
Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_4_6.jpg
RNA Expression
Figure 4 RNA cell line category:Cell line enhanced (U-2197)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185010-F8
❮
❯
Specifications
- Host Species
- Human
- Derivation
- Human phage display scFv library
- Type
- Human Fab
- Specificity
- Human F8
- Species Reactivity
- Human
- Clone
- KM38
- Applications
- WB, ELISA, FuncS
- Related Disease
- Hemophilia A
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
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Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| FAMAB-0037JF-S(P) | Human Anti-F8 Recombinant Antibody (clone MH8); scFv Fragment | IP, ELISA, FuncS | Human scFv |
| FAMAB-0038JF-S(P) | Human Anti-F8 Recombinant Antibody (clone DH10); scFv Fragment | IP, ELISA, FuncS | Human scFv |
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| FAMAB-0201JF-S(P) | Human Anti-F8 Recombinant Antibody (clone KM38); scFv Fragment | WB, ELISA, FuncS | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-014LC | Recombinant Anti-Human F8 Antibody (Fab glycosylation) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| Gly-015LC | Recombinant Anti-Human F8 Antibody (Non-glycosylated) | ELISA | Human antibody |
| CAT | Product Name | Application | Type |
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| MOB-1608MZ | Recombinant Mouse Anti-Human F8 Antibody (clone 023) | ELISA, WB | Mouse antibody |
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| FAMAB-0038JF | Human Anti-F8 Recombinant Antibody (clone DH10) | WB, IF, ELISA, Dot | Human IgG |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
|---|---|---|---|
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| CAT | Product Name | Application | Type |
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| VS-0525-YC76 | Recombinant Anti-F8 (A2 domain x C1 domain) Biparatopic Antibody, Tandem scFv (Clone JM4 x Clone KM33) | ELISA | Tandem scFv |
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