Human Anti-F8 Recombinant Antibody (clone KM38); scFv Fragment (CAT#: FAMAB-0201JF-S(P))
Recombinant monoclonal antibody specially binds to A3-C1 domains of factor VIII. This human anti-F8 antibody (KM38) is not directed against amino acid residues E1649-R1689, a recently described epitope for factor VIII inhibitors in the acidic region at the amino-terminus of the factor VIII light chain. The epitope of this product overlaps with that of antibody CLB-CAg 12, a noninhibitory mAb directed against the A3-C1 domains of factor VIII.
Specific Inquiry
Normal Tissue
RNA Expression
Figure 1 Colon
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_7_3.jpg
(Endothelial cells
Staining:Medium
Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_7_3.jpg
Figure 2 Kidney
(Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_7_5.jpg
(Cells in glomeruli
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
Cells in tubules
Staining:High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_7_5.jpg
Figure 3 Testis
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_4_6.jpg
(Leydig cells
Staining:Medium
Intensity: Moderate
Quantity: 75%-25%)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/18777/41664_A_4_6.jpg
Figure 4 RNA cell line category:Cell line enhanced (U-2197)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185010-F8
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185010-F8
Specifications
- Host Species
- Human
- Derivation
- Human phage display scFv library
- Type
- Human scFv
- Specificity
- Human F8
- Species Reactivity
- Human
- Clone
- KM38
- Applications
- WB, ELISA, FuncS
- Related Disease
- Hemophilia A
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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Antibody Magnetic Beads
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NAB-930-VHH | Recombinant Anti-Human F8 VHH Single Domain Antibody | ELISA, Neut, ICC, FC | Llama VHH |
Customer Reviews and Q&As
Customer Review
Q&As
Great Technical Support
Technical support was very helpful when I had questions about optimizing conditions for my assay. Highly recommend.
Dependable Results
Provided dependable results in all experiments. The specificity and sensitivity are exactly what I needed.
Well-Documented Instructions
The antibody came with detailed instructions and datasheets, which made experimental setup straightforward.
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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