This product is a recombinant human scFv that recognizes human AILIM. The antibody AIH5D3 (JMab-136) is cross-reactive with human AILIM, Mouse AILIM, and Rat AILIM. It is capable of controlling a variety of biological reactions (for example, cell proliferation, cytokine production, immune cytolysis, cell death, induction of ADCC, etc.) associated with AILIM-mediated costimulatory signal (secondary signal) transduction. Furthermore, it has been revealed that AIH5D3 (JMab-136) is effective to treat and prevent various diseases associated with AILIM-mediated costimulatory signal transduction, being capable of inhibiting the onset and/or advancement of the diseases.
Figure 1 Human Anti-ICOS Recombinant Antibody (clone JMab-136); scFv Fragment, gggc tag (HPAB-0052-YJ-S(P)) in SDS-PAGE
Lane 1: Non-reduced scFv
Lane 2: Reduced scFv
Figure 2 Human Anti-ICOS Recombinant Antibody (clone JMab-136); scFv Fragment, gggc tag (HPAB-0052-YJ-S(P)) in WB
Western blot analysis of HPAB-0052-YJ-S(P) was performed by loading recombinant Human ICOS with hFc-tag.
HPAB-0052-YJ-S(P) incubation concentration: 2 ng/μL.
The secondary antibody: HRP-Anti-his tag antibody
Lane 1: Reducing Antigen (0.1 μg)
Lane 2: Reducing Antigen (0.3 μg)
Lane 3: Reducing Antigen (0.6 μg)
Figure 3 Human Anti-ICOS Recombinant Antibody (clone JMab-136); scFv Fragment, gggc tag (HPAB-0052-YJ-S(P)) in ELISA
ELISA analysis of HPAB-0052-YJ-S(P) was performed by coating with recombinant Human ICOS with hFc-tag.
The secondary antibody: HRP-Anti-his tag antibody
Figure 4 Human Anti-ICOS Recombinant Antibody (clone JMab-136); scFv Fragment, gggc tag (HPAB-0052-YJ-S(P)) in DB
Dot Blot analysis of HPAB-0052-YJ-S(P) was performed by coating with recombinant Human ICOS with hFc-tag.
The secondary antibody: HRP-Anti-his tag antibody
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Download resources about recombinant antibody development and antibody engineering to boost your research.
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-128CT | Mouse Anti-ICOS Recombinant Antibody (TAB-128CT) | ELISA, WB | Mouse IgG |
TAB-128CT-S(P) | Mouse Anti-ICOS Recombinant Antibody; scFv Fragment (TAB-128CT-S(P)) | ELISA, WB | Mouse scFv |
TAB-128CT-F(E) | Mouse Anti-ICOS Recombinant Antibody; Fab Fragment (TAB-128CT-F(E)) | ELISA, WB | Mouse Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
TAB-129CT | Human Anti-ICOS Recombinant Antibody (TAB-129CT) | ELISA, Neut | Human IgG2, κ |
TAB-129CT-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (TAB-129CT-S(P)) | ELISA, Neut | Human scFv |
TAB-129CT-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (TAB-129CT-F(E)) | ELISA, Neut | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
MOB-2311MZ | Recombinant Mouse Anti-Human ICOS Antibody (clone 26-525), APC-Conjugated | FC | Mouse antibody |
HPAB-0022LY | Human Anti-ICOS Recombinant Antibody (HPAB-0022LY) | Inhib, WB, IHC, ELISA | Human IgG |
FN-034CQ | Mouse Anti-ICOS Recombinant Antibody (clone ANC6C6) | ELISA, FC, FuncS | Mouse IgG1, κ |
FN-184CQ | Hamster Anti-ICOS Recombinant Antibody (clone C398.4A) | FC, FuncS | Hamster IgG |
HPAB-0052-YJ | Human Anti-ICOS Recombinant Antibody (clone JMab-136) | ELISA | Human IgG2, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-941CQ | Mouse Anti-ICOS Recombinant Antibody (clone CBL817) | Neut, FC, CyTOF | Mouse IgG1 |
NEUT-942CQ | Rat Anti-Icos Recombinant Antibody (clone 7E.17G9) | FC, FuncS, Neut | Rat IgG2b, κ |
CAT | Product Name | Application | Type |
---|---|---|---|
NEUT-943CQ | Rat Anti-Icos Recombinant Antibody (clone mAb0857) | Block, FC | Rat IgG2 |
CAT | Product Name | Application | Type |
---|---|---|---|
MOR-1727 | Rabbit Anti-ICOS Recombinant Antibody (clone DS1727AB) | IHC-P | Rabbit IgG |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0109-CN-S(P) | Hamster Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0109-CN-S(P)) | ELISA, FC, IHC | Hamster scFv |
HPAB-0073-WJ-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0073-WJ-S(P)) | ELISA | Human scFv |
HPAB-0022LY-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-0022LY-S(P)) | WB | Human scFv |
HPAB-1261WJ-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-1261WJ-S(P)) | Neut, ELISA | Human scFv |
HPAB-1262WJ-S(P) | Human Anti-ICOS Recombinant Antibody; scFv Fragment (HPAB-1262WJ-S(P)) | Neut, ELISA | Human scFv |
CAT | Product Name | Application | Type |
---|---|---|---|
HPAB-0073-WJ-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-0073-WJ-F(E)) | ELISA | Human Fab |
HPAB-0022LY-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-0022LY-F(E)) | WB | Human Fab |
HPAB-0052-YJ-F(E) | Human Anti-ICOS Recombinant Antibody (clone JMab-136); Fab Fragment | ELISA | Human Fab |
HPAB-1261WJ-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-1261WJ-F(E)) | Neut, ELISA | Human Fab |
HPAB-1262WJ-F(E) | Human Anti-ICOS Recombinant Antibody; Fab Fragment (HPAB-1262WJ-F(E)) | Neut, ELISA | Human Fab |
CAT | Product Name | Application | Type |
---|---|---|---|
VS3-WK1522 | Human Anti-ICOS Recombinant Antibody (clone JTX-2011) | ELISA, FC | Humanized IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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