Mouse Anti-KIT Monoclonal Antibody (clone 1C5) (CAT#: VS7-0425-WR221)
This product is a mouse IgG1 antibody that binds to human KIT. The antibody 1C5 can be used for WB and IHC assays.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line HEK 293
(Immunofluorescent staining of human cell line HEK 293 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73252/1469_D7_6_selected.jpg
(Immunofluorescent staining of human cell line HEK 293 shows localization to plasma membrane.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/73252/1469_D7_6_selected.jpg
Figure 2 High expression in breast
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4471/ihc_selected.jpg
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/4471/ihc_selected.jpg
Figure 3 High expression in lung.
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3288/8181_A_1_4_val_selected.jpg
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3288/8181_A_1_4_val_selected.jpg
Figure 4 Skin
(Melanocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3288/8181_B_8_1.jpg
(Melanocytes Staining: High Intensity: Strong Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/3288/8181_B_8_1.jpg
Figure 5 RNA cell line category: Group enriched (HEL, HMC-1)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157404-KIT
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000157404-KIT
Specifications
- Immunogen
- Recombinant human KIT fragment expressed in E. Coli.
- Host Species
- Mouse
- Type
- Mouse IgG1
- Specificity
- Human KIT
- Species Reactivity
- Human
- Clone
- 1C5
- Molecule Class
- Receptor Tyrosine Kinas
- Applications
- WB, IHC
- Conjugate
- Unconjugated
- Related Disease
- Piebald trait (PBT); Gastrointestinal stromal tumor (GIST); Testicular germ cell tumor (TGCT); Leukemia, acute myelogenous (AML); Mastocytosis, cutaneous (MASTC); Mastocytosis, systemic (MASTSYS)
Product Property
- Clonality
- Monoclonal
- Purity
- >95% as determined by SDS-PAGE and SEC-HPLC analysis
- Format
- Liquid
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- 0.03% sodium azide
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
- Shipping
- Ice packs
Applications
- Application Notes
- Western Blot: 1:500 - 1:2000
Immunohistochemistry-Paraffin: 1:200 - 1:1000
Enzyme-linked Immunosorbent Assay: 1:10000
Target
- Alternative Names
- KIT; v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog; PBT; SCFR; C-Kit; CD117; mast/stem cell growth factor receptor Kit; p145 c-kit; proto-oncogene c-Kit; piebald trait protein; soluble KIT variant 1; tyrosine-protein kinase Kit; proto-onco
- Gene ID
- 3815
- UniProt ID
- A0A024RDA0
- Long Name
- KIT Proto-Oncogene Receptor Tyrosine Kinase
- Cellular Localization
- Cell membrane; Cytoplasm; Membrane
- Post Translation Modifications
- Disulfide bond; Glycoprotein; Phosphoprotein; Ubl conjugation
- Protein Refseq
- NP_000213.1
- Function
- Kinase; Receptor; Transferase; Tyrosine-protein kinase
Recommended Products
Isotype Control
Secondary Antibody
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-470CL | Human Anti-KIT Recombinant Antibody (TAB-470CL) | ELISA, WB | Human IgG |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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