Chicken Anti-PRNP Recombinant Antibody (clone phAb4-31); Fab Fragment

Name: Chicken Anti-PRNP Recombinant Antibody (clone phAb4-31); Fab Fragment
SKU: FAMAB-0050-CN-F(E)
Rating: 5 (1 reviews)

CAT#: FAMAB-0050-CN-F(E)

The chicken antibody phAb4-31 reacts specifically with recombinant mouse prion protein (rPrP) (Genbank accession nos. VH: AB206326, VL: AB206327).

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to nuclear membrane & cytosol.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/if_selected.jpg

Subcellular Location Figure 2 IHC staining of human cerebellum

Immunohistochemical staining of human cerebellum shows moderate cytoplasmic positivity in Purkinje cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/ihc_selected.jpg

Normal Tissue Figure 3 Cerebral cortex

Neuropil
Staining:

Medium

Intensity: Moderate
Quantity:>75%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42754/95550_B_7_5.jpg

Normal Tissue Figure 4 Caudate

Neuronal cells
Staining:

Medium

Intensity: Strong
Quantity: <25%
Location: Cytoplasmic/
membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/43398/95554_B_9_7.jpg

Normal Tissue Figure 5 Colon

Endothelial cells
Staining:

Medium

Intensity: Moderate
Quantity: 75%-25%

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/42754/95550_A_9_3.jpg

RNA Expression Figure 6 RNA cell line category: Cell line enhanced (WM-115)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000171867-PRNP

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Specifications

Host Species
Chicken

Derivation
Phage display library

Type
Chicken Fab

Specificity
Mouse Prnp

Species Reactivity
Mouse

Clone
phAb4-31

Applications
ELISA

Product Property

Purity
>95% as determined by SDS-PAGE and HPLC analysis

Concentration
Please refer to the vial label for the specific concentration.

Buffer
PBS

Preservative
No preservatives

Storage
Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.

Target

Alternative Names
PrP; PrPC; Sinc; CD230; PrPSc; Prn-i; Prn-p; PrP; AA960666; AI325101; prP27-30; prP33-35C

Gene ID
19122

UniProt ID
P04925

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Downloadable Resources

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Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - FAMAB-0050-CN-F(E).pdf

MSDS

MSDS - FAMAB-0050-CN-F(E).pdf

COA

Certificate of Analysis Lookup

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