Human Anti-TGFBR2 Recombinant Antibody (clone TGF3)
CAT#: HPAB-0726-CN
This product is a recombinant antibody that specifically binds to the extracellular domain of human TGFβ receptor II (TGFβRII). The mAb TGF3 exhibits intermediate or minimal cross reactivity with mouse TGFβRII. However, mAb TGF3 does not block human TGFβ1 binding to mouse TGFβRII.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line HeLa
Immunofluorescent staining of human cell line HeLa shows localization to plasma membrane.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73537/if_selected.jpg
RNA Expression
Figure 2 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, HSkMC, LHCN-M2, TIME)
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163513-TGFBR2
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Specifications
- Immunogen
- Recombinant TGFβRII-Fc protein
- Host Species
- Human
- Type
- Human IgG1
- Specificity
- Human TGFBR2
- Species Reactivity
- Human, Mouse (minimal)
- Clone
- TGF3
- Applications
- WB, ELISA
- Related Disease
- Cancer, fibrosis, fibrotic diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Transforming Growth Factor Beta Receptor 2; Transforming Growth Factor, Beta Receptor II (70/80kDa); Transforming Growth Factor Beta Receptor II; TGF-Beta Type II Receptor; EC 2.7.11.30; TbetaR-II; TGFR-2; Transforming Growth Factor, Beta Receptor II Epsilon; Transforming Growth Factor, Beta Receptor II Alpha; Transforming Growth Factor, Beta Receptor II Delta; Transforming Growth Factor, Beta Receptor II Gamma; Transforming Growth Factor Beta Receptor Type IIC; Transforming Growth Factor, Beta Receptor II Beta; Transforming Growth Factor-Beta Receptor Type II; TGF-Beta Receptor Type IIB;
- Gene ID
- 7048
- UniProt ID
- P37173
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Related Signaling Pathways
JAK-STAT Signaling Pathway
TGF-β Signaling Pathway
Related Diseases
Pancreatic Cancer
Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
See other products for "Clone TGF3"
- CAT
- Product Name
See other products for "TGFBR2"
Select a product category from the dropdown menu below to view related products.
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-644CT | Anti-Human TGFβRII Recombinant Antibody (TR4B16) | ELISA, WB, FC, Inhibit | Human antibody |
| TAB-645CT | Anti-Human TGFβRII Recombinant Antibody (TR4C175) | ELISA, WB, FC, Inhibit | Human antibody |
| TAB-646CT | Anti-Human TGFβRII Recombinant Antibody (TR4D204) | ELISA, WB, FC, Inhibit | Human antibody |
| TAB-647CT | Anti-Human TGFβRII Recombinant Antibody (TR4D455) | ELISA, WB, FC, Inhibit | Human antibody |
| TAB-648CT | Anti-Human TGFβRII Recombinant Antibody (TR4D465) | ELISA, WB, FC, Inhibit | Human antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOR-3552 | Rabbit Anti-TGFBR2 Recombinant Antibody (clone DS3552AB) | WB | Rabbit IgG |
| MOR-4762 | Rabbit Anti-TGFBR2 Recombinant Antibody (clone TH276DS) | WB, IF, ICC, FC | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0232-YC-S(P) | Human Anti-TGFBR2 Recombinant Antibody (clone TGF1); scFv Fragment | ELISA, FuncS | Humanized scFv |
| HPAB-0150-FY-S(P) | Human Anti-TGFBR2 Recombinant Antibody (clone LY3022859); scFv Fragment | ELISA | Human scFv |
| HPAB-0726-CN-S(P) | Human Anti-TGFBR2 Recombinant Antibody (clone TGF3); scFv Fragment | WB, ELISA | Human scFv |
| HPAB-N0262-YC-S(P) | Human Anti-TGFBR2 Recombinant Antibody (clone Antibody A); scFv Fragment | Block | Human scFv |
| HPAB-J0240-YC-S(P) | Human Anti-TGFBR2 Recombinant Antibody (clone TGF2); scFv Fragment | ELISA, Block | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0232-YC-F(E) | Human Anti-TGFBR2 Recombinant Antibody (clone TGF1); Fab Fragment | ELISA, FuncS | Humanized Fab |
| HPAB-0150-FY-F(E) | Human Anti-TGFBR2 Recombinant Antibody (clone LY3022859); Fab Fragment | ELISA | Human Fab |
| HPAB-0726-CN-F(E) | Human Anti-TGFBR2 Recombinant Antibody (clone TGF3); Fab Fragment | WB, ELISA | Human Fab |
| HPAB-N0262-YC-F(E) | Human Anti-TGFBR2 Recombinant Antibody (clone Antibody A); Fab Fragment | Block | Human Fab |
| HPAB-J0240-YC-F(E) | Human Anti-TGFBR2 Recombinant Antibody (clone TGF2); Fab Fragment | ELISA, Block | Human Fab |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0150-FY | Human Anti-TGFBR2 Recombinant Antibody (clone LY3022859) | ELISA | Human IgG |
| HPAB-N0262-YC | Human Anti-TGFBR2 Recombinant Antibody (clone Antibody A) | Block | Human IgG |
| MOB-113LC | Rabbit Anti-TGFBR2 Recombinant Antibody (MOB-113LC) | FC, ICC, IF, WB | Rabbit IgG |
| VS3-FY1447 | Recombinant Mouse Anti-TGFBR2 Antibody (clone 2C10-2G4-6C8) | IHC-P | Mouse IgG1 |
| VS-0723-WK104 | Human Anti-TGFBR2 Recombinant Antibody (VS-0723-WK104) | FC | Chimeric (rabbit/human) IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MHC-YF745 | A*02:01/Human TGF-beta receptor type-2 (RLSSCVPVA) MHC Pentamer | FCM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-FY52 | Human Anti-TGFBR2 (clone LY3022859) scFv-Fc Chimera | Block, ADCC (weak), ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC106 | Recombinant Anti-TGFBR2 Vesicular Antibody, EV Displayed (VS-0425-YC106) | ELISA, FC, Inhib, Cell-uptake |
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