Human Anti-TGFBR2 Recombinant Antibody (clone TGF3); scFv Fragment (CAT#: HPAB-0726-CN-S(P))
This is a monoclonal antibody that specifically binds to the extracellular domain of human TGFβ receptor II (TGFβRII). The mAb TGF3 exhibits intermediate or minimal cross reactivity with mouse TGFβRII. However, mAb TGF3 does not block human TGFβ1 binding to mouse TGFβRII.
Specific Inquiry
Subcellular Location
RNA Expression
Figure 1 IF staining of human cell line HeLa
(Immunofluorescent staining of human cell line HeLa shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73537/if_selected.jpg
(Immunofluorescent staining of human cell line HeLa shows localization to plasma membrane.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/73537/if_selected.jpg
Figure 2 RNA cell line category: Cell line enhanced (ASC diff, ASC TERT1, HSkMC, LHCN-M2, TIME)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163513-TGFBR2
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000163513-TGFBR2
Specifications
- Immunogen
- Recombinant TGFβRII-Fc protein
- Host Species
- Human
- Type
- Human scFv
- Specificity
- Human TGFBR2
- Species Reactivity
- Human, Mouse (minimal)
- Clone
- TGF3
- Applications
- WB, ELISA
- Related Disease
- Cancer, fibrosis, fibrotic diseases
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
- Alternative Names
- Transforming Growth Factor Beta Receptor 2; Transforming Growth Factor, Beta Receptor II (70/80kDa); Transforming Growth Factor Beta Receptor II; TGF-Beta Type II Receptor; EC 2.7.11.30; TbetaR-II; TGFR-2; Transforming Growth Factor, Beta Receptor II Epsilon; Transforming Growth Factor, Beta Receptor II Alpha; Transforming Growth Factor, Beta Receptor II Delta; Transforming Growth Factor, Beta Receptor II Gamma; Transforming Growth Factor Beta Receptor Type IIC; Transforming Growth Factor, Beta Receptor II Beta; Transforming Growth Factor-Beta Receptor Type II; TGF-Beta Receptor Type IIB;
- Gene ID
- 7048
- UniProt ID
- P37173
Related Resources
JAK-STAT Signaling Pathway
TGF-β Signaling Pathway
Pancreatic Cancer
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
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IgG Antibody Products
Human Antibody Products
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Fab Antibody Products
MHC Tetramer Products for Cancer
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-2430z | Mouse Anti-TGFBR2 Recombinant Antibody (clone 19A2) | WB, ELISA, FC | Mouse IgG1 |
| MOB-2022CT | Recombinant Mouse anti-Human TGFBR2 Monoclonal antibody (NN0067-5G25) | FC, IHC-Fr, IHC-P, WB | |
| HPAB-0726-CN | Human Anti-TGFBR2 Recombinant Antibody (clone TGF3) | WB, ELISA | Human IgG1 |
| VS3-CJ920 | Mouse Anti-TGFBR2 Recombinant Antibody (VS3-CJ920) | IHC | Mouse IgG1 |
| VS-0723-WK104 | Human Anti-TGFBR2 Recombinant Antibody (VS-0723-WK104) | FC | Chimeric (rabbit/human) IgG1 |
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For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
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