1 0
Cart
    Inquiry
    Popular Searches: Recombinant Antibody MHC Tetramer T cell Receptor Scaffold Protein
    + Filter
    Loading...
    Custom Services order now ship next day

    MUC1 & CD3

    Loading...

    Anti-MUC1 & CD3 Products

    • TRX4 (Gly-002CL)
      Go to compare Compare
    • Anti-CanAg (clone huC242)-SPDB-[3H]DM4 ADC (ADC-214LZY)
      • Target: CanAg
      • Linker: SPDB(N-succinimidyl 4-(2-pyridyldithio)butyrate)
      • Drug: [3H]DM4([3H]N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
      Go to compare Compare
    • Anti-CanAg (clone huC242)-SMCC-[3H]DM1 ADC (ADC-213LZY)
      • Target: CanAg
      • Linker: SMCC (4-[N-maleimidomethyl] cyclohexane-1 carboxylhydrazide).
      • Drug: [3H]DM1([3H]N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
      Go to compare Compare
    • Anti-CanAg (clone huC242)-SPP-[3H]DM1 ADC (ADC-212LZY)
      • Target: CanAg
      • Linker: SPP(N-succinimidyl 4-(2-pyridyldithio)pentanoate)
      • Drug: [3H]DM1([3H]N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
      Go to compare Compare
    • Anti-CanAg (clone huC242)-SPP-DM1 ADC (ADC-209LZY)
      • Target: CanAg
      • Linker: SPP(N-succinimidyl 4-(2-pyridyldithio)pentanoate)
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
      Go to compare Compare
    • Anti-Mucin1-DM4 ADC (ADC-112LZY)
      • Target: Mucin1
      • Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
      Go to compare Compare
    • Anti-CanAg (clone huC242)-SMCC-DM1 ADC (ADC-102LZY)
      • Target: CanAg
      • Linker: SMCC (4-[N-maleimidomethyl] cyclohexane-1 carboxylhydrazide).
      • Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
      Go to compare Compare
    • Anti-CanAg (clone huC242)-SPDB-DM4 ADC (ADC-092LZY)
      • Target: CanAg
      • Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
      • Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
      Go to compare Compare
    • Anti-CA6 (clone huDS6)-SPDB-DM4 ADC (ADC-012LZY)
      • Target: CA6, a specific glycol-epitope of MUC-1
      • Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
      • Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
      Go to compare Compare
    • Anti-CAIX-mcc-MMAE ADC (ADC-013LCT)
      • Target: CAIX, Carbonic anhydrase IX
      • Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
      • Drug: MMAE (Monomethyl auristatin E)
      Go to compare Compare
    • Anti-CanAg (huC242)-SPP-DM1 ADC (ADC-012LCT)
      • Target: CanAg
      • Linker: SPP (N-succinimidyl-4-(2-pyridyldithio)pentanoate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
      Go to compare Compare
    • Anti-CanAg (huC242)-Sulfo-SPDB-DM4 ADC (ADC-010LCT)
      • Target: CanAg
      • Linker: sulfo-SPDB (sulfo-N-succinimidyl 4-(2-pyridyldithio)butyrate
      • Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
      Go to compare Compare
    • Anti-CanAg (huC242)-SMCC-DM1 ADC (ADC-009LCT)
      • Target: CanAg
      • Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
      • Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
      Go to compare Compare
    View More Products

    Can't find the products you're looking for? Try to filter in the left sidebar.Filter By Tag

    More Infomation

    Our customer service representatives are available 24 hours a day, from Monday to Sunday. Contact Us

    For Research Use Only. Not For Clinical Use.


    Background

    The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
    This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
    MUC1 & CD3
    Go to compare

    Go to compare