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MUC1 & CD3

Anti-MUC1 & CD3 Products
- Mouse Anti-CD3 Recombinant Antibody (TAB-0416CL) (TAB-0416CL)
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- Application: FC, IB, ELISA
- Mouse Anti-CD3 Recombinant Antibody Fab Fragment (TAB-0416CL-F(E)) (TAB-0416CL-F(E))
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- Application: IB, ELISA, FC, FuncS
- Mouse Anti-CD3 Recombinant Antibody scFv Fragment (TAB-0416CL-S(P)) (TAB-0416CL-S(P))
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- Application: IB, ELISA, FC, FuncS
- Humanized Anti-Human CD3 Recombinant Antibody (TAB-0418CL)
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- Type: Humanized Antibody
- Application: ELISA, FC, FuncS
- Humanized Anti-Human CD3 Recombinant Antibody Fab Fragment (TAB-0418CL-F(E))
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- Type: Humanized Antibody
- Application: ELISA, FC, FuncS
- Chimeric Anti-Human CD3 Recombinant Antibody (TAB-072LC)
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
- Anti-Human CD3 Recombinant Antibody (TAB-071LC)
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
- Chimeric Anti-Human CD3 Recombinant Antibody scFv Fragment (TAB-072LC-S(P))
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- Derivation: Chimeric (mouse/human)
- Type: Chimeric antibody (mouse/human)
- Application: ELISA
- Human Anti-Human CD3 Recombinant Antibody Fab Fragment (TAB-0532CL-F(E))
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- Type: Human antibody
- Human Anti-Human CD3 Recombinant Antibody (TAB-0532CL)
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- Type: Human antibody
- Human Anti-Human CD3 Recombinant Antibody scFv Fragment (TAB-0532CL-S(P))
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- Type: Human antibody
- Human Anti-MUC1 Recombinant Antibody; scFv Fragment (TAB-0278CL-S(P)) (TAB-0278CL-S(P))
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- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA, Internalization, BI, FuncS
- Human Anti-MUC1 Recombinant Antibody; Fab Fragment (TAB-0278CL-F(E)) (TAB-0278CL-F(E))
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- Species Reactivity: Human
- Type: Human Fab
- Application: ELISA, Internalization, BI, FuncS
- Human Anti-MUC1 Recombinant Antibody (TAB-0278CL) (TAB-0278CL)
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- Species Reactivity: Human
- Type: Human IgG
- Application: ELISA, Internalization, BI, FuncS
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-083LC-S(P)) (TAB-083LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-081LC-S(P)) (TAB-081LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-080LC-S(P)) (TAB-080LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-079LC-S(P)) (TAB-079LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-078LC-S(P)) (TAB-078LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-077LC-S(P)) (TAB-077LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-076LC-S(P)) (TAB-076LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-075LC-S(P)) (TAB-075LC-S(P))
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human scFv
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody (TAB-098LC) (TAB-098LC)
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- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus Monkey
- Type: Humanized IgG
- Application: ELISA, SPR
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- Derivation: Humanized
- Type: Humanized antibody
- Application: FC, ELISA
- Human Anti-CD3 Recombinant Antibody (TAB-100LC) (TAB-100LC)
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- Derivation: Humanized
- Species Reactivity: Human, Cynomolgus Monkey
- Type: Humanized IgG
- Application: ELISA, SPR
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1 - kappa
- Application: IF, IP, Neut, FuncS, ELISA, FC, ICC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Humanized (from mouse) IgG1, κ
- Application: IP, IF, FuncS, FC, Neut, ELISA, ICC
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: IgG1
- Application: WB, ELISA, FC, IP, FuncS, IF, Neut
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Fab fragment
- Application: ELISA
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- Derivation: Humanized
- Species Reactivity: Human
- Type: IgG1, κ
- Application: FuncS, Inhib
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- Derivation: Humanized (from mouse)
- Species Reactivity: Human
- Type: Fab - G1 - kappa
- Application: Neut, ELISA, IF, IP, FuncS, FC, IHC
- Human Anti-CD3 Recombinant Antibody (TAB-096LC) (TAB-096LC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG1
- Application: FC, WB
- Human Anti-CD3 Recombinant Antibody (TAB-095LC) (TAB-095LC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG1
- Application: FC, WB
- Human Anti-CD3 Recombinant Antibody (TAB-094LC) (TAB-094LC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Human IgG1
- Application: FC, WB
- Anti-Human CD3 Recombinant Antibody (TAB-093LC) (TAB-093LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
- Anti-Human CD3 Recombinant Antibody (TAB-092LC) (TAB-092LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
- Anti-Human CD3 Recombinant Antibody (TAB-091LC) (TAB-091LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
- Anti-Human CD3 Recombinant Antibody (TAB-090LC) (TAB-090LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC, FuncS
- Anti-Human CD3 Recombinant Antibody (TAB-089LC) (TAB-089LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC, FuncS
- Anti-Human CD3 Recombinant Antibody (TAB-088LC) (TAB-088LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
- Anti-Human CD3 Recombinant Antibody (TAB-087LC) (TAB-087LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
- Anti-Human CD3 Recombinant Antibody (TAB-086LC) (TAB-086LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC
- Anti-Human CD3 Recombinant Antibody (TAB-085LC) (TAB-085LC)
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- Derivation: Humanized
- Type: Humanized antibody
- Application: ELISA, FC, FuncS
- Human Anti-CD3 Recombinant Antibody (TAB-084LC) (TAB-084LC)
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- Species Reactivity: Human
- Type: Humanized IgG
- Application: ELISA
- Human Anti-CD3 Recombinant Antibody (TAB-083LC) (TAB-083LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody (TAB-081LC) (TAB-081LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC
- Human Anti-CD3 Recombinant Antibody (TAB-080LC) (TAB-080LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
- Human Anti-CD3 Recombinant Antibody (TAB-079LC) (TAB-079LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
- Human Anti-CD3 Recombinant Antibody (TAB-078LC) (TAB-078LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
- Human Anti-CD3 Recombinant Antibody (TAB-077LC) (TAB-077LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
- Human Anti-CD3 Recombinant Antibody (TAB-076LC) (TAB-076LC)
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- Derivation: Humanized
- Species Reactivity: Cynomolgus, Human
- Type: Human IgG1, κ
- Application: ELISA, FC, FuncS
- Human Anti-CD3 Recombinant Antibody (TAB-075LC) (TAB-075LC)
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- Derivation: Humanized
- Species Reactivity: Human
- Type: Humanized antibody
- Application: ELISA, FC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG1, κ
- Application: WB, FC, IF, IHC
- Rat Anti-CD3 Recombinant Antibody (clone 17A2) (MOB-0202MC)
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- Species Reactivity: Mouse
- Type: Rat IgG2b, κ
- Application: FC, IHC, IP, Activ, CMCD, Depletion
- Mouse Anti-MUC1 Recombinant Antibody (PABL-662)
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse IgG
- Application: WB, IF, FuncS
- Anti-Mouse CD3 Recombinant Antibody Fab Fragment (Dow2) (TAB-0365CL-F(E))
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- Application: IP, IB, FuncS
- Mouse Anti-CD3 Recombinant Antibody (TAB-0422CL) (TAB-0422CL)
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-0422CL-S(P)) (TAB-0422CL-S(P))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse scFv
- Application: ELISA
- Anti-Mouse CD3 Recombinant Antibody (Dow2) (TAB-0365CL)
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- Application: FC, IHC
- Mouse Anti-Human MUC1 Recombinant Antibody Fab Fragment (TAB-0388CL-F(E))
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- Application: WB, IHC
- Mouse Anti-Human MUC1 Recombinant Antibody (TAB-0388CL)
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- Application: WB, IHC
- Mouse Anti-Human MUC1 Recombinant Antibody scFv Fragment (TAB-0388CL-S(P))
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- Application: WB, IHC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab (IgG1, κ)
- Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
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- Derivation: Mouse
- Species Reactivity: Human
- Type: IgG
- Application: WB, FuncS, IF, Neut, ELISA, FC, IP
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse scFv
- Application: WB, IF, FuncS
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- Derivation: Mouse
- Species Reactivity: Human
- Type: Mouse Fab
- Application: WB, IF, FuncS
- anti-MUC1 immunotoxin H23 (scFv)-PE (AGTO-L064E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
- anti-MUC1 immunotoxin C242 (Fab)-PE (AGTO-L036E)
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- Species Reactivity: Human
- Application: Cytotoxicity assay, Functional assay
- Recombinant Anti-human MUC1 VHH Single Domain Antibody (NAB-2049-VHH)
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- Species Reactivity: Human
- Type: Llama VHH
- Application: WB, IP, ChiP, Neut, ELISA
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- Target: MUC-1
- Species Reactivity: Human
- Cytokine 1: IL2
- Host: Chimeric (Human-Mouse)
- Cytokine 1 Species: Human
- Molecule Class: scFv-Fc-IL2
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-070LC-S(P)) (TAB-070LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody (TAB-099LC) (TAB-099LC)
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- Species Reactivity: Cynomolgus, Human
- Type: Mouse IgG
- Application: ELISA, SPR
- Mouse Anti-CD3 Recombinant Antibody (TAB-097LC) (TAB-097LC)
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- Species Reactivity: Cynomolgus, Human
- Type: Mouse IgG
- Application: ELISA, SPR
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-074LC-S(P)) (TAB-074LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody; scFv Fragment (TAB-073LC-S(P)) (TAB-073LC-S(P))
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- Species Reactivity: Human
- Type: Mouse scFv
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody (TAB-074LC) (TAB-074LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody (TAB-073LC) (TAB-073LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA, FC
- Mouse Anti-CD3 Recombinant Antibody (TAB-070LC) (TAB-070LC)
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- Species Reactivity: Human
- Type: Mouse IgG
- Application: ELISA
- Mouse Anti-CD3 Recombinant Antibody; Fab Fragment (TAB-0422CL-F(E)) (TAB-0422CL-F(E))
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- Species Reactivity: Human, Cynomolgus monkey
- Type: Mouse Fab
- Application: ELISA
- Anti-Mouse CD3 Recombinant Antibody scFv Fragment (Dow2) (TAB-0365CL-S(P))
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- Application: IP, IB, FuncS
- TRX4 (Gly-002CL)
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- Anti-mucin repeats (clone ch3A5)-vc-MMAF ADC (ADC-220LZY)
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- Target: mucin repeats
- Linker: VC (valine-citrulline)
- Drug: MMAF (monomethyl auristatin F)
- Anti-mucin repeats (clone ch3A5)-mc-MMAF ADC (ADC-219LZY)
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- Target: mucin repeats
- Linker: mc (maleimidocaproyl)
- Drug: MMAF (monomethyl auristatin F)
- Anti-CanAg (clone huC242)-SPDB-[3H]DM4 ADC (ADC-214LZY)
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- Target: CanAg
- Linker: SPDB(N-succinimidyl 4-(2-pyridyldithio)butyrate)
- Drug: [3H]DM4([3H]N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
- Anti-CanAg (clone huC242)-SMCC-[3H]DM1 ADC (ADC-213LZY)
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- Target: CanAg
- Linker: SMCC (4-[N-maleimidomethyl] cyclohexane-1 carboxylhydrazide).
- Drug: [3H]DM1([3H]N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CanAg (clone huC242)-SPP-[3H]DM1 ADC (ADC-212LZY)
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- Target: CanAg
- Linker: SPP(N-succinimidyl 4-(2-pyridyldithio)pentanoate)
- Drug: [3H]DM1([3H]N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CanAg (clone huC242)-SPP-DM1 ADC (ADC-209LZY)
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- Target: CanAg
- Linker: SPP(N-succinimidyl 4-(2-pyridyldithio)pentanoate)
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-MUC1 (clone hPAM4)-CL2A-SN-38 ADC (ADC-162LZY)
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- Target: MUC1
- Linker: CL2A
- Drug: SN-38(7-ethyl-10-hydroxy camptothecin)
- Anti-Mucin1-DM4 ADC (ADC-112LZY)
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- Target: Mucin1
- Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
- Anti-CanAg (clone huC242)-SMCC-DM1 ADC (ADC-102LZY)
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- Target: CanAg
- Linker: SMCC (4-[N-maleimidomethyl] cyclohexane-1 carboxylhydrazide).
- Drug: DM1(N2'-deacetyl-N2'-(3-mercapto-1-oxopropyl)-maytansine)
- Anti-CanAg (clone huC242)-SPDB-DM4 ADC (ADC-092LZY)
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- Target: CanAg
- Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
- Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
- Anti-CA6 (clone huDS6)-SPDB-DM4 ADC (ADC-012LZY)
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- Target: CA6, a specific glycol-epitope of MUC-1
- Linker: SPDB (N-succinimidyl 4-(2-pyridyldithio)butyrate)
- Drug: DM4(N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
- Anti-CAIX-mcc-MMAE ADC (ADC-013LCT)
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- Target: CAIX, Carbonic anhydrase IX
- Linker: mcc (Maleimidomethyl cyclohexane-1-carboxylate)
- Drug: MMAE (Monomethyl auristatin E)
- Anti-CanAg (huC242)-SPP-DM1 ADC (ADC-012LCT)
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- Target: CanAg
- Linker: SPP (N-succinimidyl-4-(2-pyridyldithio)pentanoate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-CanAg (huC242)-SPDB-DM4 ADC (ADC-011LCT)
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- Target: CanAg
- Linker: SPDB
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
- Anti-CanAg (huC242)-Sulfo-SPDB-DM4 ADC (ADC-010LCT)
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- Target: CanAg
- Linker: sulfo-SPDB (sulfo-N-succinimidyl 4-(2-pyridyldithio)butyrate
- Drug: DM4 (N2'-Deacetyl-N2'-(4-mercapto-4-methyl-1-oxopentyl)maytansine)
- Anti-CanAg (huC242)-SMCC-DM1 ADC (ADC-009LCT)
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- Target: CanAg
- Linker: SMCC (N-succinimidyl 4-(Nmaleimidomethyl)cyclohexane-1-carboxylate)
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-CanAg (huC242)-Mal-dPEG4-NHS-DM1 ADC (ADC-008LCT)
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- Target: CanAg
- Linker: PEG4Mal
- Drug: DM1 (N2'-Deacetyl-N2'-(3-mercapto-1-oxopropyl)maytansine)
- Anti-mucin (clone hPAM4)-SN-38 ADC (ADC-121CL)
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- Target: mucin
- Drug: SN-38 (7-ethyl-10-hydroxycamptothecin)
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- Targets: MUC1 & CD3
- Type: Fab2
- Application: FuncS, Promising therapeutic agent
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For Research Use Only. Not For Clinical Use.
The protein encoded by this gene is part of the T-cell receptor/CD3 complex (TCR/CD3 complex) and is involved in T-cell development and signal transduction. The encoded membrane protein represents the delta subunit of the CD3 complex, and along with four other CD3 subunits, binds either TCR alpha/beta or TCR gamma/delta to form the TCR/CD3 complex on the surface of T-cells. Defects in this gene are a cause of severe combined immunodeficiency autosomal recessive T-cell-negative/B-cell-positive/NK-cell-positive (SCIDBNK). Two transcript variants encoding different isoforms have been found for this gene. Other variants may also exist, but the full-length natures of their transcripts has yet to be defined.
This gene encodes a membrane-bound protein that is a member of the mucin family. Mucins are O-glycosylated proteins that play an essential role in forming protective mucous barriers on epithelial surfaces. These proteins also play a role in intracellular signaling. This protein is expressed on the apical surface of epithelial cells that line the mucosal surfaces of many different tissues including lung, breast stomach and pancreas. This protein is proteolytically cleaved into alpha and beta subunits that form a heterodimeric complex. The N-terminal alpha subunit functions in cell-adhesion and the C-terminal beta subunit is involved in cell signaling. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. This gene is known to contain a highly polymorphic variable number tandem repeats (VNTR) domain. Alternate splicing results in multiple transcript variants.
