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    Mouse Anti-Human MUC1 Recombinant Antibody scFv Fragment (CAT#: TAB-0388CL-S(P))

    This antibody scFv fragment relates generally to the fields of medicine research, oncology research and immunodiagnostics research. More particularly, it concerns the development of immunoreagents for use in diagnosing. This antibody binds to the MUC1 cytoplasmic domain. Mice were immunized with the protein that contained the cytoplasmic domain of MUC1 fused to GST (GST-CD). The summarized results showed that the epitope for the MUC1-CD specific antibody scFv fragment is present between amino acids 8-15 of the MUC1-CD protein. The amino acid sequence of the epitope is YGQLDIFP.

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    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    We require custom production
    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location and Protein Expression
    Figure 1 IF staining of human cell line RPTEC TERT1
    Figure 1 IF staining of human cell line RPTEC TERT1
    (Immunofluorescent staining of human cell line RPTEC TERT1 shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8855/1789_B9_13_cr596f381e20667_selected.jpg
    Figure 2 IHC staining of human stomach
    Figure 2 IHC staining of human stomach
    (Immunohistochemical staining of human stomach shows strong membranous positivity in glandular cells.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1986/ihc_selected.jpg
    Figure 3 IF staining of human cell line A-431
    Figure 3 IF staining of human cell line A-431
    (Immunofluorescent staining of human cell line A-431 shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8855/100_E7_1_blue_red_green.jpg
    Figure 4 IF staining of human cell line U-2 OS
    Figure 4 IF staining of human cell line U-2 OS
    (Immunofluorescent staining of human cell line U-2 OS shows localization to plasma membrane.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/8855/101_E7_1_blue_red_green.jpg
    Normal Tissue
    Figure 5 Stomach
    Figure 5 Stomach
    (Glandular cells
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Location: Cytoplasmic/membranous)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36/155175_A_2_1.jpg
    Figure 6 Colon
    Figure 6 Colon
    (Endocrine cells
    Staining:High
    Intensity: Strong
    Enterocytes
    Staining:High
    Intensity: Strong
    Quantity: 75%-25%
    Goblet cells
    Staining:High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36/155175_A_9_3.jpg
    Figure 7 Kidney
    Figure 7 Kidney
    (Collecting ducts
    Staining:High
    Intensity: Strong
    Quantity:>75%
    Distal tubules
    Staining:High
    Intensity: Strong
    Quantity:>75%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36/155175_A_8_5.jpg
    Figure 8 Testis
    Figure 8 Testis
    (Elongated or late spermatids
    Staining:Medium
    Intensity: Moderate
    Quantity: 75%-25%)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/36/155175_A_6_6.jpg
    RNA Expression
    Figure 9 RNA cell line category: Group enriched (CAPAN-2, OE19, RPTEC TERT1, T-47d)
    Figure 9 RNA cell line category: Group enriched (CAPAN-2, OE19, RPTEC TERT1, T-47d)
    (Cell lines ordered by descending RNA expression order.)
    * Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000185499-MUC1

    Specifications

    • Immunogen
    • GST-MUC1 (CD) protein
    • Host Species
    • Mouse
    • Specificity
    • Human
    • Related Disease
    • MUCl-positive cancers

    Target

    • Alternative Names
    • MUC1; mucin 1, cell surface associated; EMA; MCD; PEM; PUM; KL-6; MAM6; MCKD; PEMT; CD227; H23AG; MCKD1; MUC-1; ADMCKD; ADMCKD1; CA 15-3; MUC-1/X; MUC1/ZD; MUC-1/SEC; mucin-1; episialin; DF3 antigen; H23 antigen; cancer antigen 15-3; krebs von den Lungen-6; mucin 1, transmembrane; carcinoma-associated mucin; polymorphic epithelial mucin; peanut-reactive urinary mucin; tumor associated epithelial mucin; breast carcinoma-associated antigen DF3; tumor-associated epithelial membrane antigen; Medullary cystic kidney disease, autosomal dominant;

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    NAB-2049-VHH Recombinant Anti-human MUC1 VHH Single Domain Antibody WB, IP, ChiP, Neut, ELISA Llama VHH
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