Mouse Anti-APP Recombinant Antibody (clone 4G8)
CAT#: EPAF-0567CQ
This product is a mouse antibody that specifically recognizes APP from human. The antibody 4G8 is an epitope-specific antibody that can be used in ELISA, IHC and other immunological assays.
Gene Expression
Subcellular Location
Figure 1 IF staining of human cell line U-2 OS
Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus & vesicles.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/if_selected.jpg
Subcellular Location
Figure 2 IF staining of human cell line A-431
Immunofluorescent staining of human cell line A-431 shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/60_E2_1_blue_red_green.jpg
Subcellular Location
Figure 3 IF staining of human cell line U-251 MG
Immunofluorescent staining of human cell line U-251 MG shows localization to the Golgi apparatus.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/1462/61_E2_1_blue_red_green.jpg
Normal Tissue
Figure 4 Cerebral cortex
Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/157/2073_B_7_5.jpg
RNA Expression
Figure 5 RNA cell line category: Low cell line specificity
Cell lines ordered by descending RNA expression order.
* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000142192-APP
❮
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Specifications
- Host Species
- Mouse
- Type
- Mouse IgG2b
- Specificity
- Human Amyloid beta A4 protein
- Species Reactivity
- Human
- Clone
- 4G8
- Applications
- ELISA, IHC
- Conjugate
- Unconjugated
Product Property
- Purity
- >95% as determined by analysis by SDS-PAGE
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
REVIEWS AND Q&AS
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Good Value for Money
Considering its performance and specificity, this antibody offers good value for money. It consistently delivers accurate results, making it a dependable tool in our lab.
User-Friendly Protocols
The inclusion of detailed protocols and guidelines is very helpful. It simplifies the setup process, ensuring that even new users can achieve optimal results.
Efficient Customer Support
Customer support from the supplier is efficient and knowledgeable. They assisted us with optimization tips that greatly improved our experimental outcomes.
Q&As
-
Does the antibody have no endotoxins?
A: Yes, there are no endotoxins in the antibody preparation.
-
Are there any particular handling guidelines that apply to this antibody?
A: It is advisable to follow standard laboratory precautions. Do not freeze-thaw repeatedly.
-
What tests for quality control are run on this antibody?
A: Testing is done on this antibody to determine its activity in pertinent applications, purity, and specificity.
View the frequently asked questions answered by Creative Biolabs Support.
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Downloadable Resources
Download resources about recombinant antibody development and antibody engineering to boost your research.
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Datasheet
MSDS
COA
Certificate of Analysis LookupTo download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number:
Protocol & Troubleshooting
We have outlined the assay protocols, covering reagents, solutions, procedures, and troubleshooting tips for common issues in order to better assist clients in conducting experiments with our products. View the full list of Protocol & Troubleshooting.
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| CAT | Product Name | Application | Type |
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| TAB-0344CL | Human Anti-APP Recombinant Antibody (TAB-0344CL) | ELISA | Human IgG |
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| TAB-0341CL-F(E) | Mouse Anti-APP Recombinant Antibody; Fab Fragment (TAB-0341CL-F(E)) | ELISA, FuncS, In vivo | Mouse Fab |
| TAB-0342CL-F(E) | Mouse Anti-APP Recombinant Antibody; Fab Fragment (TAB-0342CL-F(E)) | ELISA, FuncS, In vivo | Mouse Fab |
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| TAB-0022CL-VHH | Anti-Human APP VHH Single Domain Antibody (TAB-0022CL-VHH) | ELISA, In vivo, FuncS | Single domain antibody |
| TAB-0023CL-VHH | Anti-Human APP VHH Single Domain Antibody (TAB-0023CL-VHH) | ELISA, In vivo, FuncS | Single domain antibody |
| CAT | Product Name | Application | Type |
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| TAB-0802CLV | Human Anti-APP Recombinant Antibody (TAB-0802CLV) | ELISA | Chimeric (mouse/human) IgG1, κ |
| TAB-0789CLV-F(E) | Human Anti-APP Recombinant Antibody; Fab Fragment (TAB-0789CLV-F(E)) | ELISA | Chimeric (mouse/human) Fab |
| TAB-0789CLV-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0789CLV-S(P)) | ELISA | Mouse scFv |
| TAB-0802CLV-S(P) | Mouse Anti-APP Recombinant Antibody; scFv Fragment (TAB-0802CLV-S(P)) | ELISA | Mouse scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| BRD-0685MZ | Chicken Anti-APP Polyclonal IgY | IHC | Chicken antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| PABX-014 | Hi-Affi™ Rabbit Anti-APP Recombinant Antibody (clone M204) | WB, ELISA, FuncS | Rabbit IgG |
| PABX-014-F (E) | Hi-Affi™ Rabbit Anti-APP Recombinant Antibody (clone M204); Fab Fragment | WB, ELISA, FuncS | Rabbit Fab |
| MOR-0220 | Hi-Affi™ Rabbit Anti-APP Recombinant Antibody (clone DS220AB) | ELISA, WB | Rabbit IgG |
| MOR-4539 | Hi-Affi™ Rabbit Anti-APP Recombinant Antibody (clone TH47DS) | IHC-P, ELISA | Rabbit IgG |
| MOR-0082-FY | Rabbit Anti-APP Recombinant Antibody (clone AFY0053) | ICC, IHC-P, WB | Rabbit IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
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| EPAF-0568CQ | Human Anti-APP Recombinant Antibody (clone HyL5) | ELISA, Inhib | Human IgM |
| EPAF-0569CQ | Mouse Anti-APP Recombinant Antibody (clone AB1-42) | IHC | Mouse IgG |
| EPAF-0570CQ | Human Anti-APP Recombinant Antibody (clone L11.3) | IHC, ELISA, Inhib | Human IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| NS-001CN | Human Anti-APP Recombinant Antibody (clone AS) | WB | Human IgG |
| NS-007CN | Mouse Anti-APP Recombinant Antibody (NS-007CN) | ELISA, FuncS | Mouse IgG1 |
| NS-001CN-F(E) | Human Anti-APP Recombinant Antibody (clone AS); Fab Fragment | WB | Human Fab |
| NS-007CN-F(E) | Mouse Anti-APP Recombinant Antibody; Fab Fragment (NS-007CN-F(E)) | ELISA | Mouse Fab |
| NS-001CN-S(P) | Human Anti-APP Recombinant Antibody (clone AS); scFv Fragment | WB | Human scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| AFC-TAB-225 | Afuco™ Anti-APP ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-225) | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-228 | Afuco™ Anti-APP ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-228) | FuncS, IF, Neut, ELISA, FC | ADCC enhanced antibody |
| AFC-TAB-229 | Afuco™ Anti-APP ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-229) | FuncS, IF, Neut, ELISA, FC, IP | ADCC enhanced antibody |
| AFC-TAB-227 | Afuco™ Anti-APP ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-227) | ELISA, IP, FC, FuncS, Neut | ADCC enhanced antibody |
| AFC-TAB-226 | Afuco™ Anti-APP ADCC Recombinant Antibody, ADCC Enhanced (AFC-TAB-226) | IF, IP, Neut, FuncS, ELISA | ADCC enhanced antibody |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0008-YJ | Mouse Anti-APP Recombinant Antibody (clone 508F) | ELISA | Mouse IgM |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0525-WJ-S(P) | Human Anti-APP Recombinant Antibody (clone h12A11); scFv Fragment | ELISA | Humanized scFv |
| HPAB-0970-FY-F(E) | Mouse Anti-APP Recombinant Antibody; Fab Fragment (HPAB-0970-FY-F(E)) | ELISA | Mouse Fab |
| HPAB-0971-FY-F(E) | Mouse Anti-APP Recombinant Antibody; Fab Fragment (HPAB-0971-FY-F(E)) | ELISA | Mouse Fab |
| HPAB-0973-FY-F(E) | Human Anti-APP Recombinant Antibody (clone E12); scFv Fragment | ELISA | Humanized scFv |
| HPAB-0974-FY-F(E) | Human Anti-APP Recombinant Antibody (clone 1C10); scFv Fragment | ELISA | Humanized scFv |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| HPAB-0970-FY | Mouse Anti-APP Recombinant Antibody (HPAB-0970-FY) | ELISA | Mouse IgG |
| HPAB-0971-FY | Mouse Anti-APP Recombinant Antibody (HPAB-0971-FY) | ELISA | Mouse IgG |
| HPAB-0973-FY | Human Anti-APP Recombinant Antibody (clone E12) | ELISA | Humanized IgG |
| HPAB-0974-FY | Human Anti-APP Recombinant Antibody (clone 1C10) | ELISA | Humanized IgG |
| HPAB-0975-FY | Human Anti-APP Recombinant Antibody (clone 4D3) | ELISA | Humanized IgG |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0424-XY17 | AbPlus™ Anti-APP Magnetic Beads (DE2B4) | IP, Protein Purification |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-1024-XY23 | Mouse Anti-NHP APP Recombinant Antibody (VS-1024-XY23) | WB, ICC | Mouse IgG1 |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0325-FY6 | Human Anti-APP (clone 2A7) scFv-Fc Chimera | ELISA | Human IgG1, scFv-Fc |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0425-YC204 | Recombinant Anti-APP Vesicular Antibody, EV Displayed (VS-0425-YC204) | ELISA, FC, Neut, Cell-uptake |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-XY469 | Anti-APP Immunohistochemistry Kit | IHC | |
| VS-0525-XY470 | Anti-Mouse APP Immunohistochemistry Kit | IHC | |
| VS-0525-XY471 | Anti-Monkey APP Immunohistochemistry Kit | IHC |
| CAT | Product Name | Application | Type |
|---|---|---|---|
| VS-0525-YC2 | Recombinant Anti-APP Biparatopic Antibody, Tandem sdAb | ELISA, Inhib | Tandem sdAb |
| VS-0525-YC18 | Recombinant Anti-APP (AA 3-7 x AA 12-28) Biparatopic Antibody, Tandem scFv (Clone h12A11v1 x Solanezumab) | ELISA, Neut, FC, IF, IP, WB | Tandem scFv |
| VS-0525-YC196 | Recombinant Anti-APP (AA 1-5 x AA 13-28) Biparatopic Antibody, Tandem scFv | ELISA, FC, IF, IP, Neut, WB | Tandem scFv |
| VS-0525-YC198 | Recombinant Anti-APP (AA 13-28 x AA 33-40) Biparatopic Antibody, Tandem scFv (Solanezumab x Ponezumab) | ELISA, FC, IF, IP, Neut, WB | Tandem scFv |
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