Afuco™ Anti-Human AXL ADCC Recombinant Antibody, ADCC Enhanced (CAT#: AFC-056CL)
Anti-AXL ADCC Enhanced Antibody is an ADCC enhanced antibody produced by our Afuco™ platform. Anti-AXL antibodies can bind to a specific region in Anexelekto (AXL) and are useful as agents for decreasing the AXL expression level, antitumor agents, and diagnostic agents for cancer.
Specific Inquiry
Subcellular Location
Normal Tissue
RNA Expression
Figure 1 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, actin filaments & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75217/1899_C1_1_selected.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, actin filaments & vesicles.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/75217/1899_C1_1_selected.jpg
Figure 2 IHC staining of human thyroid gland
(Immunohistochemical staining of human thyroid gland shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32501/ihc_selected.jpg
(Immunohistochemical staining of human thyroid gland shows strong cytoplasmic positivity in glandular cells.)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/32501/ihc_selected.jpg
Figure 3 Skeletal muscle
(Myocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_B_1_6.jpg
(Myocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_B_1_6.jpg
Figure 4 Colon
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_8_3.jpg
(Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_8_3.jpg
Figure 5 Kidney
(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_9_5.jpg
(Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_9_5.jpg
Figure 6 Testis
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_4_6.jpg
(Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
* Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_4_6.jpg
Figure 7 RNA cell line category: Cell line enhanced (fHDF/TERT166, U-251 MG)
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167601-AXL
(Cell lines ordered by descending RNA expression order)
* Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167601-AXL
Specifications
- Host Species
- Humanized
- Derivation
- Humanized
- Type
- ADCC enhanced antibody
- Species Reactivity
- Human
- Related Disease
- Cancer
Product Property
- Purity
- >98% by SDS-PAGE and HPLC analysis
- Storage
- Store it under sterile conditions at -20°C upon receiving. Recommend to pack the protein into smaller quantities for optimal storage.
Target
- Alternative Names
- AXL; AXL receptor tyrosine kinase; ARK; UFO; JTK11; Tyro7
- Gene ID
- 558
- UniProt ID
- P30530
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "AXL"
Select a product category from the dropdown menu below to view related products.
Please select product type
Mouse Antibody Products
Chimeric Antibody Products
Humanized Antibody Products
Rabbit Monoclonal Antibody Products
IgG Antibody Products
ScFv Antibody Products
Fab Antibody Products
Antibody Magnetic Beads
Non-Human Primate (NHP) Antibody Products
Flow Cytometry (FC) related Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-1087CL | Human Anti-AXL Recombinant Antibody (TAB-1087CL) | ADCC | Chimeric (mouse/human) IgG1, κ |
| TAB-0188CL-F(E) | Mouse Anti-AXL Recombinant Antibody; Fab Fragment (TAB-0188CL-F(E)) | WB, FuncS, ELISA, FC | Mouse Fab |
| TAB-1087CL-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (TAB-1087CL-F(E)) | ELISA, FuncS | Chimeric (mouse/human) Fab |
| TAB-1088CL-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (TAB-1088CL-F(E)) | ELISA, FuncS | Chimeric (mouse/human) Fab |
| TAB-1089CL-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (TAB-1089CL-F(E)) | ELISA, FuncS | Chimeric (mouse/human) Fab |
Customer Reviews and Q&As
Customer Review
Q&As
Great For Signal Assays
We used this antibody to detect AXL in signal transduction assays and found it to be highly sensitive. The ADCC enhancement is a notable advantage for our cytotoxicity studies.
Minimal Cross-Reactivity
We've tested this antibody across various AXL-expressing and non-expressing cell lines. The specificity is impressive with minimal cross-reactivity, making it reliable for our targeted studies.
Effective in Blocking AXL
We observed effective neutralization of AXL receptor signaling, which provided us valuable insights into AXL's role in cancer metastasis.
Popular products with customers
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC
Application: WB, IHC, ELISA, FC
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: ELISA, IHC, FC, IP, IF, FuncS
Application: FC, IA, IF, IP, IHC, FuncS
Application: ELISA, IF, Block, FuncS
Application: ELISA, WB, Microarray, Block
Application: FC
Application: ELISA, WB
Application: WB, IHC-Fr, IHC-P, ICC, IF
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
