Mouse Anti-AXL Recombinant Antibody (clone AXL225) (CAT#: HPAB-0113-LS)
The anti-AXL antibody has an angiogenesis-suppressing effect and a cancer-suppressing effect.
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Custom Production
We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.
We require custom production
FuncS
Figure 1 The activity of an anti-AXL monoclonal antibody (Ax225), in inducing AXL downmodulation in cancer cells.
The antibody was shown to induce the downmodulation of AXL protein.
FuncS
Figure 2 The antitumor effects of the anti-AXL monoclonal antibodies (Ax223, Ax285, Ax96, Ax292, Ax258, Ax7, Ax51, Ax284, and Ax225) in a mouse xenograft model of human pancreatic adenocarcinoma.
FuncS
Figure 3 The antitumor effects of an anti-AXL monoclonal antibody (Ax225) in a mouse xenograft model of human breast cancer.
Specifications
- Immunogen
- AXL
- Host Species
- Mouse
- Type
- Mouse IgG
- Specificity
- Human AXL
- Species Reactivity
- Human, Mouse
- Clone
- AXL225
- Applications
- Inhib, FuncS
- Related Disease
- Squamous cell cancer, Small-cell lung cancer, Gastric cancer, Pancreatic cancer
Product Property
- Purity
- >95% as determined by SDS-PAGE and HPLC analysis
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Applications
- Application Notes
- This antibody has been tested for use in Functional Assay.
Target
Related Resources
EGFR Tyrosine Kinase Inhibitor Resistance
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
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Extracellular Vesicle (EV) Antibody Products
| CAT | Product Name | Application | Type |
|---|---|---|---|
| TAB-0189CL | Human Anti-AXL Recombinant Antibody (TAB-0189CL) | WB, FuncS, ELISA, FC | Chimeric (Mouse/Human) IgG1, κ |
| TAB-0189CL-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (TAB-0189CL-F(E)) | WB, FuncS, ELISA, FC | Chimeric (Mouse/Human) Fab |
| TAB-1090CL-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (TAB-1090CL-F(E)) | ELISA, FuncS | Chimeric (mouse/human) Fab |
| TAB-1091CL-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (TAB-1091CL-F(E)) | ELISA, FuncS | Chimeric (mouse/human) Fab |
| TAB-1092CL-F(E) | Human Anti-AXL Recombinant Antibody; Fab Fragment (TAB-1092CL-F(E)) | ELISA, FuncS | Chimeric (mouse/human) Fab |
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For Research Use Only. Not For Clinical Use.
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