Anti-Human AXL Recombinant Antibody (1613F12) (CAT#: TAB-1093CL)

The anti-AXL antibody 1613F12 targets AXL. The antibody can be used in the treatment of cancers, such as breast cancer, NSCLC, pancreas cancer, lung cancer and renal cancer

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Cyt

Figure 1 In vitro cytotoxicity assay using Mab-zap conjugated secondary antibody on SN12C cells.

Figure 1 In vitro cytotoxicity assay using Mab-zap conjugated secondary antibody on SN12C cells.

ELISA

Figure 2 A, B and C: Binding specificity of 1613F12 on the immobilized rhAxl-Fc protein (A), rhDtk-Fc (B) or rhMer-Fc (C) proteins by ELISA.

Figure 2 A, B and C: Binding specificity of 1613F12 on the immobilized rhAxl-Fc protein (A), rhDtk-Fc (B) or rhMer-Fc (C) proteins by ELISA.

FC

Figure 3 FACS analysis of the 1613F12 binding on human tumor cells.

Figure 3 FACS analysis of the 1613F12 binding on human tumor cells.

ELISA

Figure 4 ELISA on the immobilized rmAxl-Fc protein (“rm” for murine recombinant).

Figure 4 ELISA on the immobilized rmAxl-Fc protein (“rm” for murine recombinant).

FC

Figure 5 1613F12 binding on COS7 cells as determined by indirect labelling protocol using flow cytometry method.

Figure 5 1613F12 binding on COS7 cells as determined by indirect labelling protocol using flow cytometry method.

ELISA

Figure 6 Competition ELISA of Gas6 binding using 1613F12.

Figure 6 Competition ELISA of Gas6 binding using 1613F12.

WB

Figure 7 Epitope binding analysis by western Blot using SN12C cell lysate.

Figure 7 Epitope binding analysis by western Blot using SN12C cell lysate.

NH (no heat); NR (no reduction); H (heat); R (reduction). GAPDH detection attests to the correct sample loading on the gel.

Figure 8 Effect of 1613F12 on in vitro SN12C cells proliferation compared to the effect of the mIgG1 isotype control antibody.

Figure 8 Effect of 1613F12 on in vitro SN12C cells proliferation compared to the effect of the mIgG1 isotype control antibody.


Specifications

  • Immunogen
  • Human extracellular domain (ECD) of the Axl receptor
  • Host Species
  • Mouse
  • Specificity
  • Human
  • Clone
  • 1613F12
  • Applications
  • ELISA, FC, Cyt, WB
  • Related Disease
  • Breast cancer, NSCLC, Pancreas cancer, Lung cancer, Renal cancer

Applications

  • Application Notes
  • This antibody has been tested for use in Enzyme-linked Immunosorbent Assay, Flow Cytometry, Cytotoxicity and Western Blot.

Target

  • Alternative Names
  • AXL; AXL receptor tyrosine kinase; ARK; UFO; JTK11; Tyro7

Related Resources

  • Related Diseases

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Downloads

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For Research Use Only. Not For Clinical Use.

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

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