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    Anti-Human AXL Recombinant Antibody scFv Fragment (hzl613F12-24 DAR2) (CAT#: TAB-0139CL-S(P))

    The humanized Axl antibody-drug conjugate consisting of a pyrrolobenzodiazepine dimer target the protein Axl, of which the overexpression is related with poor prognosis and increased invasiveness of a variety of human cancers such as breast, colon, esophageal carcinoma, osteosarcoma and so on.

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    We specialize in custom recombinant antibody production, offering seamless execution from provided sequences to high-quality antibody deliverables, ensuring optimal yield and purity.

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    • Gene Expression
    • Datasheet
    • MSDS
    • COA
    Subcellular Location
    Figure 1 IF staining of human cell line U-251 MG
    Figure 1 IF staining of human cell line U-251 MG
    (Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, actin filaments & vesicles.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/75217/1899_C1_1_selected.jpg
    Normal Tissue
    Figure 2 IHC staining of human thyroid gland
    Figure 2 IHC staining of human thyroid gland
    (Immunohistochemical staining of human thyroid gland shows strong cytoplasmic positivity in glandular cells.)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/32501/ihc_selected.jpg
    Figure 3 Skeletal muscle
    Figure 3 Skeletal muscle
    (Myocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_B_1_6.jpg
    Figure 4 Colon
    Figure 4 Colon
    (Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_8_3.jpg
    Figure 5 Kidney
    Figure 5 Kidney
    (Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_9_5.jpg
    Figure 6 Testis
    Figure 6 Testis
    (Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_4_6.jpg
    RNA Expression
    Figure 7 RNA cell line category: Cell line enhanced (fHDF/TERT166, U-251 MG)
    Figure 7 RNA cell line category: Cell line enhanced (fHDF/TERT166, U-251 MG)
    (Cell lines ordered by descending RNA expression order)
    * Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167601-AXL

    Specifications

    • Host Species
    • Human
    • Type
    • Humanized Antibody
    • Specificity
    • Human
    • Clone
    • hzl613F12-24 DAR2
    • Related Disease
    • Breast, colon, esophageal carcinoma, osteosarcoma, renal cancer

    Target

    • Alternative Names
    • AXL; AXL receptor tyrosine kinase; ARK; UFO; JTK11; Tyro7

    Related Resources

    • Related Diseases

    Product Notes

    This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

    • Increased sensitivity
    • Confirmed specificity
    • High repeatability
    • Excellent batch-to-batch consistency
    • Sustainable supply
    • Animal-free production

    See more details about Hi-Affi™ recombinant antibody benefits.

    Downloads

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    CAT Product Name Application Type
    TAB-0335CL Anti-Human AXL Recombinant Antibody (Ax225 (was demonstrated to recognize FND1 of AXL)) WB, FuncS, ELISA
    TAB-0336CL Anti-Human AXL Recombinant Antibody WB, FuncS, ELISA
    TAB-1087CL Human Anti-AXL Recombinant Antibody (TAB-1087CL) ADCC Chimeric (mouse/human) IgG1, κ
    TAB-1088CL Human Anti-AXL Recombinant Antibody (TAB-1088CL) ADCC Chimeric (mouse/human) IgG1, κ
    TAB-1089CL Human Anti-AXL Recombinant Antibody (TAB-1089CL) ELISA, FuncS Chimeric (mouse/human) IgG1, κ

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