Anti-Human AXL Recombinant Antibody scFv Fragment (Ax225 (was demonstrated to recognize FND1 of AXL))

Name: Anti-Human AXL Recombinant Antibody scFv Fragment (Ax225 (was demonstrated to recognize FND1 of AXL))
SKU: TAB-0335CL-S(P)
Rating: 5 (1 reviews)

CAT#: TAB-0335CL-S(P)

The Anti-AXL antibody is an full mouse monoclonal antibody that specifically bind to anexelekto, which is a receptor tyrosine kinase and is said to be responsible for signal transduction to downstream molecules through its autophosphorylation and involved in cell growth enhancement, suppression of apoptosis, cell migration, and cell adhesion. The AXL-specific antibody herein can exert an angiogenesis-suppressive effect and an antitumor effect by inhibiting phosphporylation activity of AXL, and therefore be used in the treatment of cancers such as pancreatic Adenocarcinoma and breast Cancer.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line U-251 MG

Immunofluorescent staining of human cell line U-251 MG shows localization to plasma membrane, actin filaments & vesicles.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/75217/1899_C1_1_selected.jpg

Normal Tissue Figure 2 IHC staining of human thyroid gland

Immunohistochemical staining of human thyroid gland shows strong cytoplasmic positivity in glandular cells.

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/32501/ihc_selected.jpg

Normal Tissue Figure 3 Skeletal muscle

Myocytes Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_B_1_6.jpg

Normal Tissue Figure 4 Colon

Glandular cells Staining: Medium Intensity: Moderate Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_8_3.jpg

Normal Tissue Figure 5 Kidney

Cells in glomeruli Staining: Low Intensity: Weak Quantity: 75%-25% Location: Cytoplasmic/ membranous Cells in tubules Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_9_5.jpg

Normal Tissue Figure 6 Testis

Cells in seminiferous ducts Staining: High Intensity: Strong Quantity: 75%-25% Location: Cytoplasmic/ membranous Leydig cells Staining: Medium Intensity: Moderate Quantity:>75% Location: Cytoplasmic/ membranous

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/images/37422/82809_A_4_6.jpg

RNA Expression Figure 7 RNA cell line category: Cell line enhanced (fHDF/TERT166, U-251 MG)

Cell lines ordered by descending RNA expression order

* Image credit: Image credit: Human Protein Atlas v21.proteinatlas.org/ENSG00000167601-AXL

❮

❯

Specifications

Immunogen
hAXL-ECD-mIgG2aFc protein (extracellular domain of human AXL fused with Fc domain of mouse IgG2a)

Host Species
Mouse

Specificity
Human

Species Reactivity
Cross-react with mouse AXL

Clone
Ax225 (was demonstrated to recognize FND1 of AXL)

Related Disease
Pancreatic Adenocarcinoma, Breast Cancer

Target

Alternative Names
AXL; AXL receptor tyrosine kinase; ARK; UFO; JTK11; Tyro7

Gene ID
558

UniProt ID
P30530

REVIEWS AND Q&AS CITATIONS RESOURCES DOWNLOADS RELATED PRODUCTS

Inquiry

Navs

Customer Review

There are currently no Customer reviews or questions for TAB-0335CL-S(P). Click the button above to contact us or submit your feedback about this product.

Submit Your Publication

Published with our product? Submit your paper and receive a 10% discount on your next order! Share your research to earn exclusive rewards.

Related Diseases

EGFR Tyrosine Kinase Inhibitor Resistance

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-0335CL-S(P).pdf

MSDS

MSDS - TAB-0335CL-S(P).pdf

COA

Certificate of Analysis Lookup

To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.

Lot Number:

See other products for "Clone Ax225 (was demonstrated to recognize FND1 of AXL)"

CAT
Product Name

See other products for "AXL"

Select a product category from the dropdown menu below to view related products.

CAT	Product Name	Application	Type
TAB-0139CL	Anti-Human AXL Recombinant Antibody (hzl613F12-24 DAR2)	ELISA, IF, FC, Inhib, ICFC	Humanized Antibody
TAB-0140CL	Anti-Human AXL Recombinant Antibody (hzl613F12-33 DAR4)	ELISA, IF, FC, Inhib, ICFC	Humanized Antibody
TAB-1094CL	Anti-Human AXL Recombinant Antibody (Hz1613F12)	ELISA, FC, Cyt	Humanized antibody
TAB-1098CL	Anti-Human AXL Recombinant Antibody (Humanized 11B7)	ELISA, FuncS	Humanized antibody
TAB-1099CL	Anti-Human AXL Recombinant Antibody (Humanized 11D5)	ELISA	Humanized antibody

CAT	Product Name	Application	Type
TAB-0188CL	Mouse Anti-AXL Recombinant Antibody (TAB-0188CL)	ELISA	Mouse IgG
TAB-0336CL-S(P)	Anti-Human AXL Recombinant Antibody scFv Fragment	WB, FuncS, ELISA
TAB-1087CL-F(E)	Human Anti-AXL Recombinant Antibody; Fab Fragment (TAB-1087CL-F(E))	ELISA, FuncS	Chimeric (mouse/human) Fab
TAB-1088CL-F(E)	Human Anti-AXL Recombinant Antibody; Fab Fragment (TAB-1088CL-F(E))	ELISA, FuncS	Chimeric (mouse/human) Fab
TAB-1089CL-F(E)	Human Anti-AXL Recombinant Antibody; Fab Fragment (TAB-1089CL-F(E))	ELISA, FuncS	Chimeric (mouse/human) Fab

CAT	Product Name	Application	Type
TAB-0189CL-S(P)	Human Anti-AXL Recombinant Antibody; scFv Fragment (TAB-0189CL-S(P))	WB, FuncS, ELISA, FC	Human scFv
TAB-1090CL-S(P)	Mouse Anti-AXL Recombinant Antibody; scFv Fragment (TAB-1090CL-S(P))	ELISA, FuncS	Mouse scFv
TAB-1091CL-S(P)	Mouse Anti-AXL Recombinant Antibody; scFv Fragment (TAB-1091CL-S(P))	ELISA, FuncS	Mouse scFv
TAB-1092CL-S(P)	Mouse Anti-AXL Recombinant Antibody; scFv Fragment (TAB-1092CL-S(P))	ELISA, FuncS	Mouse scFv
TAB-1071CLV	Human Anti-AXL Recombinant Antibody (TAB-1071CLV)	ADCC, FuncS	Chimeric (mouse/human) IgG1, κ

CAT	Product Name	Application	Type
MOR-3970	Hi-Affi™ Rabbit Anti-AXL Recombinant Antibody (clone SI30DS)	ELISA	Rabbit IgG

CAT	Product Name	Application	Type
HPAB-1783LY-F(E)	Mouse Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-1783LY-F(E))	ELISA, IHC	Mouse Fab
HPAB-1850LY-F(E)	Mouse Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-1850LY-F(E))	ELISA, IA, FC, IHC, WB, IP	Mouse Fab
HPAB-1851LY-F(E)	Mouse Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-1851LY-F(E))	ELISA, IA, FC, IHC, WB, IP	Mouse Fab
HPAB-1852LY-F(E)	Mouse Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-1852LY-F(E))	ELISA, IA, FC, IHC, WB, IP	Mouse Fab
HPAB-1853LY-F(E)	Mouse Anti-AXL Recombinant Antibody; Fab Fragment (HPAB-1853LY-F(E))	ELISA, IA, FC, IHC, WB, IP	Mouse Fab

CAT	Product Name	Application	Type
HPAB-1850LY	Mouse Anti-AXL Recombinant Antibody (HPAB-1850LY)	ELISA, IA, FC, IHC, WB, IP	Mouse IgG
HPAB-1851LY	Mouse Anti-AXL Recombinant Antibody (HPAB-1851LY)	ELISA, IA, FC, IHC, WB, IP	Mouse IgG
HPAB-1852LY	Mouse Anti-AXL Recombinant Antibody (HPAB-1852LY)	ELISA, IA, FC, IHC, WB, IP	Mouse IgG
HPAB-1853LY	Mouse Anti-AXL Recombinant Antibody (HPAB-1853LY)	FC, SPR, IHC, WB, ELISA, IA, FC, IP	Mouse IgG
HPAB-1854LY	Mouse Anti-AXL Recombinant Antibody (HPAB-1854LY)	ELISA, IA, FC, IHC, WB, IP	Mouse IgG

CAT	Product Name	Application	Type
HPAB-1850LY-S(P)	Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1850LY-S(P))	ELISA, IA, FC, IHC, WB, IP	Mouse scfv
HPAB-1851LY-S(P)	Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1851LY-S(P))	ELISA, IA, FC, IHC, WB, IP	Mouse scfv
HPAB-1852LY-S(P)	Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1852LY-S(P))	ELISA, IA, FC, IHC, WB, IP	Mouse scfv
HPAB-1853LY-S(P)	Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1853LY-S(P))	ELISA, IA, FC, IHC, WB, IP	Mouse scfv
HPAB-1854LY-S(P)	Mouse Anti-AXL Recombinant Antibody; scFv Fragment (HPAB-1854LY-S(P))	ELISA, IA, FC, IHC, WB, IP	Mouse scfv

CAT	Product Name	Application	Type
VS-0424-XY26	AbPlus™ Anti-AXL Magnetic Beads (VS-0424-XY26)	IP, Protein Purification

CAT	Product Name	Application	Type
VS-1024-XY44	Rabbit Anti-NHP AXL Recombinant Antibody (VS-1024-XY44)	WB, IF, IP	Rabbit IgG

CAT	Product Name	Application	Type
VS-0225-XY2	CytoStream™ Rat Anti-AXL Recombinant Antibody (clone 175128)	FC	Rat IgG2a, kappa

CAT	Product Name	Application	Type
VS-0425-FY66	Human Anti-AXL (clone Enapotamab) scFv-Fc Chimera	ELISA	Human IgG1, scFv-Fc

CAT	Product Name	Application	Type
VS-0425-YC363	Recombinant Anti-AXL Vesicular Antibody, EV Displayed (VS-0425-YC363)	ELISA, FC, Inhib, Cell-uptake

CAT	Product Name	Application	Type
VS-0525-YC20	Recombinant Anti-AXL (AA 1-134 x AA 222-234) Biparatopic Antibody, Tandem scFv	Block, ELISA, FC, IHC, SPR, WB	Tandem scFv

Specific Inquiry

Size:

Conjugation:

Endotoxin:

Purity:

Formats:

Isotype Switching:

Fc Engineering:

Modalities:

Add to compare

Request
Custom Production

See Our Custom Production in Action

Figure 1 Anti-HBV Recombinant Antibody (TAB-147) in SDS-PAGE

Download the full case study

Popular Products

Figure 2 Human Anti-ERBB3 Recombinant Antibody (TAB-189) in ELISA

Human Anti-ERBB3 Recombinant Antibody (TAB-189) (CAT# TAB-189)
Application: IP, IF, FuncS, FC, Neut, ELISA, ICC

Figure 2 Anti-EGFR Recombinant Antibody (TAB-710) in ELISA

Anti-EGFR Recombinant Antibody (Nimotuzumab) (CAT# TAB-710)
Application: ELISA, IP, FC, FuncS, Neut, IF, IHC

Figure 11 Blockade of PD-1/PD-L1 interaction by anti-PD-1 antibody (Cat# TAB-H55) resulted in an increase of IFN-γ production.

Human Anti-PDCD1 Recombinant Antibody (TAB-H55) (CAT# TAB-H55)
Application: Inhib, Agonist

Figure 5 Anti-Human Mesothelin Recombinant Antibody (TAB-201) in HPLC

Anti-Human Mesothelin Recombinant Antibody (TAB-201) (CAT# TAB-201)
Application: IP, IF, FuncS, FC, Neut, ELISA, IHC

Figure 4 Anti-Human IL1 beta Recombinant Antibody (TAB-161) in ELISA

Anti-Human IL1 beta Recombinant Antibody (TAB-161) (CAT# TAB-161)
Application: ELISA, FC, IP, FuncS, IF, Neut, ICC

Figure 2 Mouse Anti-GM3 Recombinant Antibody (PABC-051) in HPLC

Mouse Anti-GM3 Recombinant Antibody (clone 14F7) (CAT# PABC-051)
Application: ELISA

Figure 5 Recombinant Human Anti-EBV BLLF1 Antibody (PABZ-138) in DB

Recombinant Human Anti-EBV BLLF1 Antibody (72A1) (CAT# PABZ-138)
Application: Neut, ELISA

Figure 6 Anti-LAM Recombinant Antibody (PABW-158, lot#CB2206LX02P6) in SEC-HPLC

Mouse Anti-LAM Recombinant Antibody (clone CS-35) (CAT# PABW-158)
Application: ELISA, IF, FC

Figure 3 Anti-Human CEACAM6 Recombinant Antibody (TAB-444LC) in DB

Anti-Human CEACAM6 Recombinant Antibody (TAB-444LC) (CAT# TAB-444LC)
Application: IHC, ELISA, FC, WB, ADCC, FuncS

Figure 2 Anti-CD5 Antibody (53-7.3) Fab Fragment (NEUT-392CQ-Fab) in ELISA

Rat Anti-CD5 Recombinant Antibody (clone 53-7.3) (CAT# NEUT-392CQ)
Application: FC, IHC-Fr, IP, ELISA, Block

Figure 3 Anti-CD276 Antibody (TAB-424CQ) in DB

Anti-Human CD276 Recombinant Antibody (TAB-424CQ) (CAT# TAB-424CQ)
Application: ELISA, IHC, FC, IP, IF, FuncS

Figure 4 Anti-Human C5 Recombinant Antibody (TAB-453CQ) in WB

Anti-Human C5 Recombinant Antibody (TAB-453CQ) (CAT# TAB-453CQ)
Application: ELISA, IHC, FC, IP, IF, FuncS

Figure 2 Recombinant Anti-ICAM1 Single Domain Antibody (HPAB-0349-YC-VHH) in ELISA

Recombinant Llama Anti-ICAM1 Single Domain Antibody (HPAB-0349-YC-VHH) (CAT# HPAB-0349-YC-VHH)
Application: ELISA

Figure 3 Rat Anti-IL18 Recombinant Antibody (HPAB-0067-YC-S(P)) in ELISA

Rat Anti-IL18 Recombinant Antibody (clone 2C10); scFv Fragment (CAT# HPAB-0067-YC-S(P))
Application: Neut

Figure 3 Mouse Anti-CEACAM6 Antibody (HPAB-0286-CN) in DB

Human Anti-CEACAM6 Recombinant Antibody (HPAB-0286-CN) (CAT# HPAB-0286-CN)
Application: ELISA, WB, FC

Figure 5 Anti-EPHA2 Recombinant Antibody (HPAB-0453-CN) in ELISA

Human Anti-EPHA2 Recombinant Antibody (clone 4H5) (CAT# HPAB-0453-CN)
Application: ELISA, FC, IF

Figure 5 Recombinant Mouse Anti-MARV GP Antibody (EPAF-0808CQ) in Dot Blot

Recombinant Mouse Anti-MARV GP Antibody (7E10) (CAT# EPAF-0808CQ)
Application: WB, IP

Figure 2 Human Anti-IFNAR1 Recombinant Antibody (HPAB-0203CQ) in WB

Human Anti-IFNAR1 Recombinant Antibody (clone H3K1) (CAT# HPAB-0203CQ)
Application: ELISA, FC, Inhib

Figure 5 Mouse Anti-VEGFA Recombinant Antibody (clone mAb G6-31) (HPAB-0330CQ) in DB

Mouse Anti-VEGFA Recombinant Antibody (clone mAb G6-31) (CAT# HPAB-0330CQ)
Application: ELISA, IF, Block, FuncS

Figure 1 Recombinant Human Anti-HBV preS1 Antibody (PABC-406) in SDS-PAGE

Recombinant Human Anti-HBV preS1 Antibody (PABC-406) (CAT# PABC-406)
Application: Neut, IHC, Activ, FuncS, IF, ELISA

For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.

Send Inquiry

This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.