Anti-Human CCL2 Recombinant Antibody Fab Fragment (MC15)

Name: Anti-Human CCL2 Recombinant Antibody Fab Fragment (MC15)
SKU: TAB-0752CL-F(E)
Rating: 5 (1 reviews)

CAT#: TAB-0752CL-F(E)

Recombinant monoclonal antibody MC15 is a human monoclonal antibody that specifically binds to human MCP-1 and can be potentially used in the treatment of chronic autoimmune disease.

Gene Expression

Subcellular Location Figure 1 IF staining of human cell line BJ

Immunofluorescent staining of human cell line BJ shows localization to the Golgi apparatus.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19163/1742_B4_8_cr580492c5c7769_selected.jpg

Subcellular Location Figure 2 IHC staining of human stomach

Immunohistochemical staining of human stomach shows strong cytoplasmic positivity in dot like pattern in glandular cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19163/ihc_selected.jpg

Subcellular Location Figure 3 IHC staining of human appendix

Immunohistochemical staining of human appendix shows strong cytoplasmic positivity in glandular cells.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13676/29298_A_2_2_selected.jpg

Subcellular Location Figure 4 IF staining of human cell line U-2 OS

Immunofluorescent staining of human cell line U-2 OS shows localization to the Golgi apparatus.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/19163/182_D1_1_blue_red_green.jpg

Normal Tissue Figure 5 Cerebral cortex

Neuronal cells
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous nuclear

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13676/29298_B_9_5.jpg

Normal Tissue Figure 6 Colon

Glandular cells
Staining: High
Intensity: Strong
Quantity:>75%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13676/29298_A_8_3.jpg

Normal Tissue Figure 7 Kidney

Cells in tubules
Staining: Medium
Intensity: Moderate
Quantity: 75%-25%
Location: Cytoplasmic/membranous

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/13676/29298_A_7_5.jpg

RNA Expression Figure 8 RNA cell line category: Group enriched (BJ hTERT+, HMC-1)

Cell lines ordered by descending RNA expression order.

* Image credit: Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000108691-CCL2

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Specifications

Host Species
Human

Derivation
Human phage display library

Type
Human antibody

Specificity
Human

Clone
MC15

Applications
ELISA

Related Disease
Chronic autoimmune disease

Target

Alternative Names
CCL2; chemokine (C-C motif) ligand 2; HC11; MCAF; MCP1; MCP-1; SCYA2; GDCF-2; SMC-CF; HSMCR30; C-C motif chemokine 2; small-inducible cytokine A2; monocyte secretory protein JE; monocyte chemotactic protein 1; monocyte chemoattractant protein 1; monocyte chemoattractant protein-1; monocyte chemotactic and activating factor; small inducible cytokine subfamily A (Cys-Cys), member 2; small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)

Gene ID
6347

UniProt ID
P13500

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Related Diseases

Rheumatoid Arthritis

Related Signaling Pathways

TNF Signaling Pathway

Downloadable Resources

Download resources about recombinant antibody development and antibody engineering to boost your research.

Product Notes

This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:

• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production

See more details about Hi-Affi™ recombinant antibody benefits.

Datasheet

Datasheet - TAB-0752CL-F(E).pdf

MSDS

MSDS - TAB-0752CL-F(E).pdf

COA

Certificate of Analysis Lookup

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