Human Anti-CD70 Recombinant Antibody; Fab Fragment (HPAB-0099-LSX-F(E)) (CAT#: HPAB-0099-LSX-F(E))
This is a human Fab fragment anti-CD70 antibody, the binding of anti-CD70 monoclonal antibody to renal cancer cell lines 786-0 and A-498 is concentration-dependent. The binding concentration of anti-CD70 monoclonal antibody to renal cancer cell line 786-0 is 10 μg/mL. The EC₅₀ value of anti-CD70 monoclonal antibody binding to 786-0 cells is 6.927 nM. The antibody is the Fab fragment antibody format of full length antibody. The Fab fragment of an antibody is capable of binding to antigens independently of the Fc portion.
Specific Inquiry
Subcellular Location and Protein Expression
RNA Expression
Figure 1 IF staining of human cell line SiHa
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1486_B2_3_selected.jpg
(Immunofluorescent staining of human cell line SiHa shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1486_B2_3_selected.jpg
Figure 2 IF staining of human cell line U-251 MG
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1559_D6_2_red_green.jpg
(Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/images/46582/1559_D6_2_red_green.jpg
Figure 3 RNA cell line category: Cell line enhanced (SiHa, THP-1, U-251 MG, U-266/70, U-266/84, U-698)
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125726-CD70
(Cell lines ordered by descending RNA expression order.)
* Image credit: Human Protein Atlas https://v21.proteinatlas.org/ENSG00000125726-CD70
Specifications
- Immunogen
- Recombinant human CD70
- Host Species
- Human
- Type
- Human Fab
- Specificity
- Human CD70
- Species Reactivity
- Human, Monkey
- Applications
- ELISA, FC
Product Property
- Purity
- >95% as determined by SDS-PAGE
- Concentration
- Please refer to the vial label for the specific concentration.
- Buffer
- PBS
- Preservative
- No preservatives
- Storage
- Centrifuge briefly prior to opening vial. Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C long term. Avoid repeated freeze/thaw cycles.
Target
Product Notes
This is a product of Creative Biolabs' Hi-Affi™ recombinant antibody portfolio, which has several benefits including:
• Increased sensitivity
• Confirmed specificity
• High repeatability
• Excellent batch-to-batch consistency
• Sustainable supply
• Animal-free production
See more details about Hi-Affi™ recombinant antibody benefits.
Downloads
Download resources about recombinant antibody development and antibody engineering to boost your research.
See other products for "CD70"
Select a product category from the dropdown menu below to view related products.
Please select product type
Recombinant Antibody
Humanized Antibody
Human Antibody
Neutralizing Antibody
Blocking Antibody
scFv Fragment Antibody
ADCC Enhanced Antibody
Fab Fragment Antibody
| CAT | Product Name | Application | Type |
|---|---|---|---|
| MOB-1584z | Mouse Anti-CD70 Recombinant Antibody (clone 24B8) | FC, IF, IHC, IP | Mouse IgG1, κ |
| MOB-1639MZ | Recombinant Mouse Anti-Human CD70 Antibody (clone CV70) | ELISA, FC, FuncS, IHC-Fr, IP | Mouse antibody |
| HPAB-M0487-YC | Rat Anti-CD70 Recombinant Antibody (clone 4F2-12) | FC | Rat IgG2a, κ |
| FN-046CQ | Mouse Anti-CD70 Recombinant Antibody (clone BU69) | ELISA, FC, Block, ICC, IHC | Mouse IgG1 |
| VS-0723-WK186 | Rabbit Anti-CD70 Recombinant Antibody (VS-0723-WK186) | ELISA, FC | Rabbit IgG |
Customer Reviews and Q&As
There are currently no Customer reviews or questions for HPAB-0099-LSX-F(E). Click the button above to contact us or submit your feedback about this product.
Popular products with customers
Application: FC, IP, ELISA, Neut, FuncS, IF, ICC
Application: Neut, ELISA, IF, IP, FuncS, FC, ICC
Application: ELISA, IHC, FC, IP, IF, Inhib
Application: FC, IHC, Cyt, FuncS
-1.jpg)
Application: FC, FuncS, IA, IF, IP, IHC
-1.jpg)
Application: FC
Application: IF, IP, Neut, FuncS, ELISA, FC
For Research Use Only. Not For Clinical Use.
For research use only. Not intended for any clinical use. No products from Creative Biolabs may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative Biolabs.
Send Inquiry
This site is protected by reCAPTCHA and the Google Privacy Policy and Terms of Service apply.
